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T36964BML-259；化合物BML-259CAY10554；CAY10554
BML-259 is an inhibitor of CDK5 and CDK2 with IC50s of 64 and 98 nM, respectively. BML-259 can be used in studies about the treatment of cancer and neurodegenerative diseases.
价 格：￥电议型 号：T36964产 地：中国大陆
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T36885BMSpep-57 hydrochloride；BMSpep-57 hydrochlorideBMSpep-57 hydrochloride
BMSpep-57 hydrochloride, a potent macrocyclic peptide, competitively inhibits PD-1/PD-L1 interaction, exhibiting an IC50 value of 7.68 nM. It binds to PD-L1 with dissociation constants (Kds) of 19 nM and 19.88 nM as determined by MST and SPR assays, respectively. This compound enhances T cell functionality by promoting IL-2 production in PBMCs[1].
价 格：￥电议型 号：T36885产 地：中国大陆
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T36884BM-1244；BM-1244BM-1244
BM-1244 is a potent Bcl-xL/Bcl-2 inhibitor with Kis of 134 and 450 nM for Bcl- xL and Bcl-2, respectively. BM-1244 inhibits senescent fibroblasts (SnCs) with an EC50 of 5 nM[1].
价 格：￥电议型 号：T36884产 地：中国大陆
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T36883BM-1074；BM-1074BM-1074
BM-1074 is a potent and highly efficacious inhibitor of Bcl-2/Bcl-xL with Ki value of < 1nM [1].
价 格：￥电议型 号：T36883产 地：中国大陆
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T36695TAS-103；TAS-103 (BMS-247615)TAS-103
TAS-103 is a dual inhibitor of DNA topoisomerase I/II, used for cancer research.
价 格：￥电议型 号：T36695产 地：中国大陆
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T3655BMS-1；化合物PD-1/PD-L1 inhibitor 1PD1-PDL1 inhibitor 1|||PD-1/PD-L1 inhibitor 1；PD1-PDL1 inhibitor 1|||
BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1 allows Ys to evade the host immune system. High tumor expression of PD-L1 was associated with increased tumor aggressiveness and a 4.5-fold increased risk of death.
价 格：￥电议型 号：T3655产 地：中国大陆
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T36139BMS-795311；BMS 795311BMS-795311
Potent cholesteryl ester transfer protein (CETP) inhibitor (IC50 = 4 nM in an enzyme-based scintillation proximity assay). Inhibits cholesteryl ester transfer and increases HDL-C levels in vivo. Orally bioavailable.
价 格：￥电议型 号：T36139产 地：中国大陆
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T35856BMS-986176；化合物BMS-986176BMS-986176
AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).
价 格：￥电议型 号：T35856产 地：中国大陆
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T35399BM213；BM213BM213；BM213
BM213是一种选择性的C5aR1激动剂，EC50为59 nM，可诱导C5aR1介导的钙动员和pERK1/2信号通路，但不能诱导β-抑制素的募集。BM213更为稳定，对SHSY-5Y 细胞无细胞毒性。
价 格：￥电议型 号：T35399产 地：中国大陆
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T35386Elotuzumab；依洛妥珠单抗Elotuzumab (anti-SLAMF7)|||BMS 901608|||PDL 063|||HuLuc 63；Elotuzumab (anti-SLAMF7)
Elotuzumab(HuLuc 63) is a monoclonal antibody that targets the SLAMF7 receptor.Elotuzumab is a compound that directly activates NK cells and induces antibody-dependent cytotoxicity, and can be used in combination with lenalidomide and dexamethasone (Ld) to treat multiple myeloma.
价 格：￥电议型 号：T35386产 地：中国大陆
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T3523Fostemsavir；磷坦姆沙韦BMS-663068；BMS-663068|||磷坦姆沙韦
Fostemsavir (BMS-663068) is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.
价 格：￥电议型 号：T3523产 地：中国大陆
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T3495Tasimelteon；他司美琼VEC-162|||BMS-214778；他司美琼|||VEC-162|||BMS-214778
Tasimelteon (BMS-214778) is a melatonin receptor agonist that is used for the treatment of non-24 hour sleep-wake disorder in blind individuals.
价 格：￥电议型 号：T3495产 地：中国大陆
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T34760SYR127063；化合物SYR127063SYR-127063|||BDBM 92454|||SYR 127063|||BDBM-92454|||BDBM92454；SYR-127063|||BDB
SYR127063 (BDBM-92454) (BDBM92454) is a potent and selective HER2 inhibitor, binds to HER2 in a reactive conformation.
价 格：￥电议型 号：T34760产 地：中国大陆
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T3462BMS-582949 hydrochloride；化合物BMS-582949 HClBMS-582949 HCl；BMS-582949 HCl
The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).
价 格：￥电议型 号：T3462产 地：中国大陆
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T34278Redaporfin化合物 T34278F 2BMet|||F2BMet|||F-2BMet|||LUZ11|||LUZ 11|||LUZ-11
Redaporfin, also known as F-2BMet or LUZ-11, is a photosensitizer for Photodynamic Therapy (PDT) of cancer. Redaporfin showed a high efficacy in the treatment of male BALB/c mice with subcutaneously implanted colon (CT26) tumours. Vascular-PDT with 1.5 mg/kg redaporfin and a light dose of 74 J/cm? led to the complete tumour regression in 83% of the mice.
价 格：￥电议型 号：T34278产 地：中国大陆
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T3424Ezutromid；依珠曲米BMN 195|||VOX-C1100|||SMT C1100；BMN 195|||VOX-C1100|||依珠曲米|||SMT C1100
Ezutromid (BMN 195) is a translation modulator of Small utrophin (EC50: 0.4 uM). Ezutromid is an orally bioavailable small molecule that transcriptionally upregulates the utrophin gene, increasing both utrophin mRNA and protein. Through this action, Ezutromid increases muscle function in dystrophin-deficient MDX mice, a mouse model of muscular dystrophy.
价 格：￥电议型 号：T3424产 地：中国大陆
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T33346Methylaminoalanine-nickel(II)；化合物 T33346L-Bmma-nickel(II)|||L-Medap-nickel(II)；L-Bmma-nickel(II)|||L
Methylaminoalanine-nickel(II) can be regarded as a naturally occurring neurotoxin.
价 格：￥电议型 号：T33346产 地：中国大陆
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T3275Nefazodone hydrochloride；萘法唑酮盐酸盐Dutonin|||MJ-13754-1|||Serzone|||BMY-13754-1|||BMY-13754；Dutonin|||M
Nefazodone hydrochloride (Serzone) is a serotoninergic modulating antidepressant that is used in therapy of depression, aggressive behavior and panic disorder.
价 格：￥电议型 号：T3275产 地：中国大陆
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T32737Liafensine；立阿芬辛BMS820836|||BMS 820836|||DB104|||BMS-820836；BMS820836|||BMS 820836|||DB104|||BMS-8208
Liafensine(BMS-820836) is a novel and selective triple monoamine reuptake inhibitor with inhibitory effects on the reuptake of serotonin, norepinephrine, and dopamine for the study of major depressive disorder and central nervous system disorders.
价 格：￥电议型 号：T32737产 地：中国大陆
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T3204BML-210；化合物BML210CAY10433；CAY10433
BML-210 (CAY10433) is a new-type HDAC inhibitor.
价 格：￥电议型 号：T3204产 地：中国大陆
