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T14617Bis-aminooxy-PEG1;化合物 T14617Bis-aminooxy-PEG1
Bis-aminooxy-PEG1 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14617产 地:中国大陆
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T14579Biotin NHS;(+)生物素-N-琥珀酰亚胺基酯Biotin-NHS|||NHS-Biotin|||Biotin N-hydroxysuccinimide ester;(+)生物素-N-琥珀酰亚
Biotin NHS (NHS-Biotin) is an amino reactive biotin reagent used to prepare biotinylated surfaces or polypeptides.
价 格:¥电议型 号:T14579产 地:中国大陆
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T14575Biotin-bis-amido-SS-NHS;化合物 T14575Biotin-bis-amido-SS-NHS
Biotin-bis-amido-SS-NHS is an alkyl/ether-based PROTAC linker that finds utility in the synthesis of PROTACs.
价 格:¥电议型 号:T14575产 地:中国大陆
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T14495Baloxavir巴洛沙韦Baloxavir acid|||S-033447
Baloxavir (S-033447) is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit.
价 格:¥电议型 号:T14495产 地:中国大陆
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T1448LDasatinib monohydrate;达沙替尼BMS-354825 Monohydrate;达沙替尼|||BMS-354825 Monohydrate
Dasatinib monohydrate (BMS-354825 Monohydrate) is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib monohydrate binds to and inhibits the growth-promoting activities of these kinases. Apparently, because of its less stringent binding affinity for the BCR-ABL kinase, Dasatinib monohydrate has been shown to overcome the resistance to imatinib of chronic myeloid leukemia (CML) cells harboring BCR-ABL kinase domain point mutations.
价 格:¥电议型 号:T1448L产 地:中国大陆
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T14486Azidoethyl-SS-PEG2-Boc;化合物 T14486Azidoethyl-SS-PEG2-Boc
Azidoethyl-SS-PEG2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14486产 地:中国大陆
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T14485Azidoethyl-SS-ethylazide;化合物 T14485Azidoethyl-SS-ethylazide
Azidoethyl-SS-ethylazide is a cleavable linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14485产 地:中国大陆
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T14484Azidoethyl-SS-ethylamine;化合物 T14484Azidoethyl-SS-ethylamine
Azidoethyl-SS-ethylamine is a cleavable linker compound employed for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14484产 地:中国大陆
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T1448Dasatinib达沙替尼BMS-354825|||达沙替尼
Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive. Dasatinib has antitumor activity and is used in the treatment of leukemia and lymphoma.
价 格:¥电议型 号:T1448产 地:中国大陆
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T14451Azido-PEG4-NHS-ester;化合物 T14451Azido-PEG4-NHS-ester
Azido-PEG4-NHS-ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14451产 地:中国大陆
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T1445Agomelatine;阿戈美拉汀Thymanax|||S-20098|||Valdoxan;Thymanax|||S-20098|||Valdoxan|||阿戈美拉汀
Agomelatine (Valdoxan) is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression.
价 格:¥电议型 号:T1445产 地:中国大陆
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T14434Azido-PEG3-SS-PEG3-azide;化合物 T14434Azido-PEG3-SS-PEG3-azide
Azido-PEG3-SS-PEG3-azide is a polyethylene glycol (PEG) based linker commonly employed in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T14434产 地:中国大陆
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T14401Azido-C2-SS-PEG2-C2-acid;化合物 T14401Azido-C2-SS-PEG2-C2-acid
Azido-C2-SS-PEG2-C2-acid is a two-unit cleavable PEG linker employed in the synthesis of antibody-drug conjugates (ADCs) [1].
价 格:¥电议型 号:T14401产 地:中国大陆
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T14392Azide-C2-SS-C2-biotin;化合物 T14392Azide-C2-SS-C2-biotin
Azide-C2-SS-C2-biotin is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14392产 地:中国大陆
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T14380AZD7507;化合物CS-2850AZD7507
AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.
价 格:¥电议型 号:T14380产 地:中国大陆
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T14339Athidathion;化合物 T14339GS-13006;GS-13006
Thiophos (GS-13006) is an insecticide, which is an organic phosphate ester.
价 格:¥电议型 号:T14339产 地:中国大陆
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T14326AS-35;化合物 AS-35AS-35
AS-35 is an orally available, selective and potent leukotrienes antagonist that inhibits LTC4, LTD4 and LTE4-induced ileus contractions.AS-35 has antiallergic properties and inhibits leukotriene synthesis.
价 格:¥电议型 号:T14326产 地:中国大陆
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T1430Betamipron;倍他米隆CS-443|||N-Benzoyl-β-alanine;CS-443|||N-Benzoyl-β-alanine|||倍他米隆
Betamipron (CS-443) is used combination with panipenem to prevent nephrotoxicity and inhibit panipenem uptake into the renal tubule.
价 格:¥电议型 号:T1430产 地:中国大陆
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T14258Aminoethyl-SS-propionic acid;化合物 T14258Aminoethyl-SS-propionic acid
Aminoethyl-SS-propionic acid is an ADC linker compound employed in ADC synthesis [1]. It functions as a cleavable linker in the conjugation of antibodies with drugs, allowing for targeted drug delivery.
价 格:¥电议型 号:T14258产 地:中国大陆
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T14257Aminoethyl-SS-ethylalcohol;化合物 T14257Aminoethyl-SS-ethylalcohol
Aminoethyl-SS-ethylalcohol (Compound 3) is an Alkyl-Chain-based PROTAC linker can be used in the synthesis of PROTACs[1]. Aminoethyl-SS-ethylalcohol is also a glutathione cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
价 格:¥电议型 号:T14257产 地:中国大陆