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T2488BAY 87-2243;化合物BAY 87-2243BAY 87-2243
BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).
价 格:¥电议型 号:T2488产 地:中国大陆
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T2396Ramatroban;雷马曲班BAY u3405;BAY u3405|||雷马曲班
Ramatroban (BAY u3405) (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis. It has been used in trials studying the treatment of Asthma.
价 格:¥电议型 号:T2396产 地:中国大陆
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T23843Butaperazine;化合物 T23843Butyrylyperazine|||Bayer 1362|||Butaperazina|||Butyrylperazine;Butyrylyperazi
Butaperazine is a typical antipsychotic of the phenothiazine class.
价 格:¥电议型 号:T23843产 地:中国大陆
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T23775BAY-958;化合物 T23775BAY 958;BAY 958
BAY-958 is a potent and selective inhibitor of PTEFb/CDK9.
价 格:¥电议型 号:T23775产 地:中国大陆
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T23654Afeletecan free base;化合物 T23654BAY 56-3722|||BAY56-3722|||BAY-563722|||Afeletecan;BAY 56-3722|||BAY5
Afeletecan is a water-soluble camptothecin derivative. Afeletecan stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. Both the initial cleavage reaction and religation steps are inhibited and subsequent collision of the replication fork with the cleaved strand of DNA results in inhibition of DNA replication, double-strand DNA breakage, and triggering of apoptosis.
价 格:¥电议型 号:T23654产 地:中国大陆
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T21864BAY-u 9773;化合物 T21864BAY-u 9773
BAY-u 9773 is a non-selective antagonist of the CysLT receptors (cysteinyl leukotrienes receptors) with about the same IC 50 for CysLT 1 and CysLT 2. BAY-u9773 is used to the inhibit LT responses [1].
价 格:¥电议型 号:T21864产 地:中国大陆
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T21712BAY 41-8543;化合物BAY 41-8543BAY 41-8543
BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).
价 格:¥电议型 号:T21712产 地:中国大陆
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T2160Suramin Sodium Salt;苏拉明钠BAY-205|||Suramin hexasodium salt|||NF-060;苏拉明钠|||BAY-205|||Suramin hexasodi
Suramin Sodium Salt (BAY-205) is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth factor I (IGF-I), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and tumor growth factor-beta (TGF-beta), to their receptors, thereby inhibiting endothelial cell proliferation and migration. This agent also inhibits vascular endothelial growth factor (VEGF)-
价 格:¥电议型 号:T2160产 地:中国大陆
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T21448Abafungin;阿巴芬净Bay w 6341|||UNII-11DI31LWXF;阿巴芬净|||Bay w 6341|||UNII-11DI31LWXF
Abafungin (Bay w 6341) is an antifungal agent with a broad-spectrum.
价 格:¥电议型 号:T21448产 地:中国大陆
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T21395Finerenone;化合物FinerenoneBAY948862|||BAY-948862|||BAY94-8862|||BAY 94-8862|||BAY-94-8862|||BAY 948862
Finerenone (BAY-948862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart failure. Finerenone (BAY-948862) displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold).
价 格:¥电议型 号:T21395产 地:中国大陆
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T21016Cyproterone;化合物 T21016BAY 94-8367|||Ciproterone|||Androcur|||SH 80881;BAY 94-8367|||Ciproterone|||An
Cyproterone, an anti-androgen, is used in combination with estrogen for the therapy of hirsutism and severe acne in females and as a palliative in prostatic carcinoma.
价 格:¥电议型 号:T21016产 地:中国大陆
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T20770BAY32-59158-羟基喹啉-2-羧酸BAY-32-5915|||BAY 32-5915|||8-羟基喹啉-2-羧酸|||BAY 32 5915
BAY32-5915 is a selective inhibitor of IKKalpha.
价 格:¥电议型 号:T20770产 地:中国大陆
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T1984LCinaciguat hydrochloride;化合物 T1984LBAY582667|||BAY58-2667|||BAY 582667|||BAY-582667|||BAY 58-2667|||
Cinaciguat( BAY582667, BAY58-2667) is a soluble guanosine cyclase activator that can prevent cardiac dysfunction in rat models of type 1 diabetes.
价 格:¥电议型 号:T1984L产 地:中国大陆
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T1984Cinaciguat;化合物CinaciguatBAY 58-2667;BAY 58-2667
Cinaciguat (BAY 58-2667) (BAY 58-2667) is the first of a new class of soluble guanylate cyclase (sGC) activators in Clinicalal development for acute decompensated heart failure.
价 格:¥电议型 号:T1984产 地:中国大陆
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T1934Bay 11-7085;化合物Bay 11-7085BAY 11-7083;BAY 11-7083
Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).
价 格:¥电议型 号:T1934产 地:中国大陆
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T19202BAY-678 racemate;化合物 T19202BAY-678 racemate
BAY-678 racemate is a racemate of BAY-678. BAY-678 is an orally bioavailable, selective and cell-permeable inhibitor of human neutrophil elastase (HNE; IC50: 20 nM).
价 格:¥电议型 号:T19202产 地:中国大陆
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T1902BAY 11-7082化合物BAY 11-7082BAY 11-7821
BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM). BAY 11-7082 is also an inhibitor of the ubiquitin-specific proteases USP7 and USP21 (IC50=0.19/0.96 μM).
价 格:¥电议型 号:T1902产 地:中国大陆
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T1792Regorafenib;瑞戈非尼BAY 73-4506|||Fluoro-Sorafenib;BAY 73-4506|||瑞戈非尼|||Fluoro-Sorafenib|||瑞格非尼
Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally active. Regorafenib has antitumor and anti-angiogenic activity.
价 格:¥电议型 号:T1792产 地:中国大陆
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T17226Vericiguat;维利西呱BAY1021189;维利西呱|||BAY1021189
Vericiguat (BAY1021189) is a potent and orally available guanylate cyclase stimulator.
价 格:¥电议型 号:T17226产 地:中国大陆
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T16986Tanomastat;化合物 T16986BAY 12-9566;BAY 12-9566
Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor. For MMP-2, MMP-3, MMP-9, MMP-13 the Ki values are 11, 143, 301, and 1470 nM respectively.
价 格:¥电议型 号:T16986产 地:中国大陆