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T16909Donafenib;多纳非尼Sorafenib (D3)|||Bay 43-9006 (D3)|||Sorafenib-d3;Sorafenib (D3)|||Bay 43-9006 (D3)|||S
Donafenib (Bay 43-9006 (D3)) is a deuterium-labeled Sorafenib which is a multikinase inhibitor(IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively).
价 格:¥电议型 号:T16909产 地:中国大陆
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T16784Roniciclib;化合物RoniciclibBAY 1000394;BAY 1000394
Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) values in the range between 5 and 25 nmol/L.
价 格:¥电议型 号:T16784产 地:中国大陆
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T16781Rogaratinib;化合物RogaratinibBAY1163877;BAY1163877
Rogaratinib (BAY1163877) is an aberrant inhibitor of fibroblast growth factor receptor (FGFR). Rogaratinib is as an orally available, selective and potent inhibitor of FGFR-1, -2 and -3 kinase activity.
价 格:¥电议型 号:T16781产 地:中国大陆
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T16576Pritelivir mesylate化合物 T16576BAY 57-1293 mesylate|||AIC316 mesylate
Pritelivir mesylate is active against herpes simplex virus types 1 and 2 (IC50: 0.02 μM against HSV1-2). Pritelivir mesylate is an inhibitor of the viral helicase-primase complex. Pritelivir mesylate shows antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection.
价 格:¥电议型 号:T16576产 地:中国大陆
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T16575Pritelivir mesylate hydrate化合物 T16575BAY 57-1293 mesylate hydrate|||AIC316 mesylate hydrate
Pritelivir mesylate hydrate is active against herpes simplex virus types 1 and 2 (IC50: 0.02 μM against HSV1-2). Pritelivir mesylate hydrate is an inhibitor of the viral helicase-primase complex. Pritelivir mesylate hydrate shows antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection.
价 格:¥电议型 号:T16575产 地:中国大陆
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T1640Ciprofloxacin环丙沙星Ciproxan|||环丙沙星|||Ciprobay|||Bay o 9867|||Bay-09867
Ciprofloxacin (Bay-09867), a synthetic broad spectrum fluoroquinolone antibiotic, inhibits bacterial DNA gyrase. It is more active against Gram-negative bacteria than Gram-positive bacteria.
价 格:¥电议型 号:T1640产 地:中国大陆
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T1617Enrofloxacin;恩诺沙星BAY-Vp2674|||PD160788;恩诺沙星|||BAY-Vp2674|||PD160788
Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.
价 格:¥电议型 号:T1617产 地:中国大陆
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T15766Lirimilast;化合物 T15766BAY 19-8004;BAY 19-8004
Lirimilast is an effective, selective, and orally active phosphodiesterase-4 (PDE4) inhibitor (IC50: 49 nM). Lirimilast has potently anti-inflammatory properties. Lirimilast can be used for the treatment of asthma or chronic obstructive pulmonary disease.
价 格:¥电议型 号:T15766产 地:中国大陆
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T1529Miglitol米格列醇BAY1099|||米格列醇|||BAY-m1099
Miglitol (BAY1099) is an alpha-Glucosidase Inhibitor with antihyperglycemic activity.
价 格:¥电议型 号:T1529产 地:中国大陆
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T15215Emiglitate;化合物 T15215BAY o 1248;BAY o 1248
Emiglitate is a selective and competitive α-glucoside hydrolase inhibitor.
价 格:¥电议型 号:T15215产 地:中国大陆
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T14998Copanlisib dihydrochloride;库潘尼西盐酸BAY 80-6946 dihydrochloride;库潘尼西盐酸|||BAY 80-6946 dihydrochloride
Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is an ATP-competitive pan-class I PI3K inhibitor (IC50s: 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ). Copanlisib dihydrochloride has superior antitumor activity and it also has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR.
价 格:¥电议型 号:T14998产 地:中国大陆
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T14511BAY1082439化合物BAY1082439N-[8-[[(2R)-2-羟基-3-(吗啉-4-基)丙基]氧基]-7-甲氧基-2,3-二氢咪唑并[1,2-C]喹唑啉-5-基]-2-甲基吡啶-3-甲酰胺
BAY1082439, an orally bioavailable, selective inhibitor of PI3Kα/β/δ, demonstrates high efficacy in inhibiting the growth of Pten-null prostate cancer [1][2]. Additionally, BAY1082439 is effective against mutated forms of PIK3CA.
价 格:¥电议型 号:T14511产 地:中国大陆
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T14510BAY-850;化合物BAY-850BAY-850
BAY-850 is a selective and potent inhibitor of adenosine triphosphatase family protein 2 (ATAD2) (IC50: 166 nM) that inhibits ovarian cancer growth and metastasis in in vitro and in vivo models.
价 格:¥电议型 号:T14510产 地:中国大陆
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T14509BAY-707;化合物 T14509BAY-707
BAY-707, a highly potent and selective substrate-competitive inhibitor of MTH1 (NUDT1) with an IC50 of 2.3 nM, is well-tolerated in mice and exhibits a favorable pharmacokinetic (PK) profile compared to other MTH1 compounds. However, it demonstrates a clear lack of anticancer efficacy both in vitro and in vivo[1].
价 格:¥电议型 号:T14509产 地:中国大陆
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T14508Bay 65-1942 hydrochloride;化合物 T14508Bay 65-1942 hydrochloride
Bay 65-1942 hydrochloride is an inhibitor of ATP-competitive and selective IKKβ.
价 格:¥电议型 号:T14508产 地:中国大陆
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T14507Bay 60-7550;化合物 Bay 60-7550BAY 607550;BAY 607550
Bay 60-7550 is a selective and potent PDE2 inhibitor (Ki: 3.8 nM) that exerts positive inotropic effects on rat heart by increasing PKA-mediated phosphorylation and can be used to ameliorate cognitive impairments and memory disorders.
价 格:¥电议型 号:T14507产 地:中国大陆
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T14506BAY 60-6583;化合物BAY 60-6583BAY 60-6583
BAY 60-6583 is a potent, high-affinity adenosine A2B receptor agonist (EC50 = 3 nM) with affinity for A2B receptors that exceeds that for A1, A2A, and A3 receptors.BAY 60-6583 is cardioprotective in a model of myocardial ischemia.The Ki values for BAY 60-6583 binding to mouse, rabbit, and dog A2BAR were 750 nM, 340 nM, and 330 nM, respectively. The Ki values of BAY 60-6583 binding to A2BAR in mice, rabbits and dogs were 750 nM, 340 nM and 330 nM respectively.
价 格:¥电议型 号:T14506产 地:中国大陆
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T14505BAY-524;化合物BAY524BAY-524
BAY-524 is an inhibitor of Bub1(IC50 = 450 nM.human Bub1 in the presence of 2 mM ATP).
价 格:¥电议型 号:T14505产 地:中国大陆
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T14504BAY 38-7271;化合物 T14504BAY 38-7271
BAY 38-7271 has strong neuroprotective properties.[1] BAY 38-7271 is selective and highly potent and cannabinoid CB1/CB2 receptor agonist. With Kis of 1.85 nM and 5.96 nM for recombinant human CB1 receptor and CB2 receptor, respectively.
价 格:¥电议型 号:T14504产 地:中国大陆
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T14503BAY-320;化合物 T14503BAY-320
BAY-320 is a Bub1 inhibitor. With an IC50 of 680 nM for human Bub1 in the presence of 2 mM ATP.
价 格:¥电议型 号:T14503产 地:中国大陆