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T1187Bifonazole；联苯苄唑Bay H-4502；联苯苄唑|||Bay H-4502
Bifonazole (Bay H-4502) acts to destabilize the fungal cytochrome p450 51 enzyme (also known as Lanosterol 14-alpha-demethylase). It works by inhibiting the production of a substance called ergosterol, which is an essential component of fungal cell membranes. This is vital in the cell membrane structure of the fungus. Its inhibition leads to cell lysis. The disruption in production of ergosterol disrupts the cell membrane and causes holes to appear. The cell membranes of fungi are vital for thei
价 格：￥电议型 号：T1187产 地：中国大陆
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T1184Rivaroxaban；利伐沙班BAY 59-7939；BAY 59-7939|||利伐沙班
Rivaroxaban (BAY 59-7939) is an orally bioavailable oxazolidinone derivative and direct inhibitor of the coagulation factor Xa with anticoagulant activity. Upon oral administration, rivaroxaban selectively binds to both free factor Xa and factor Xa bound in the prothrombinase complex. This interferes with the conversion of prothrombin (factor II) to thrombin and eventually prevents the formation of cross-linked fibrin clots. Rivaroxaban does not affect existing thrombin levels.
价 格：￥电议型 号：T1184产 地：中国大陆
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T1165Ethionamide乙硫异烟胺Bayer 5312|||乙硫异烟胺|||2-ethylthioisonicotinamide|||Ethinamide
Ethionamide (2-ethylthioisonicotinamide) is a nicotinamide derivative, with antibacterial activity, used to treat tuberculosis. Although the exact mechanism of action of ethionamide is unknown, it may inhibit the synthesis of mycolic acid, a saturated fatty acid found in the bacterial cell wall, thereby inhibiting bacterial cell wall synthesis. This eventually leads to bacterial cell wall disruption and cell lysis. Ethionamide may be bacteriostatic or bactericidal in action, depending on the con
价 格：￥电议型 号：T1165产 地：中国大陆
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T11577BAY 59-9435；化合物 T11577HSL-IN-2；HSL-IN-2
HSL-IN-2 is a selective inhibitor of Hormone Sensitive Lipase (HSL; IC50: 0.023 μM).
价 格：￥电议型 号：T11577产 地：中国大陆
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T1146Nifedipine；硝苯地平BAY-a-1040|||Procardia XL|||Procardia|||Adalat；BAY-a-1040|||Procardia XL|||Procardia|
Nifedipine (Procardia) is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents.
价 格：￥电议型 号：T1146产 地：中国大陆
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T1061Toltrazuril；妥曲珠利BAY-i 9142|||Toltrazurilo|||Baycox|||Toltrazurilum；BAY-i 9142|||Toltrazurilo|||妥曲珠利|
Toltrazuril (Toltrazurilo), an antiprotozoal agent, has effect on Coccidia parasites.
价 格：￥电议型 号：T1061产 地：中国大陆
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T10518BET-BAY 002；化合物 T10518BET-BAY 002
BET-BAY 002 is an effective BET inhibitor and exhibits efficacy in a multiple myeloma model.
价 格：￥电议型 号：T10518产 地：中国大陆
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T10517BET-BAY 002 (S enantiomer)；化合物 T10517BET-BAY 002 (S enantiomer)
The S-enantiomer of BET-BAY 002, referred to as BET-BAY 002 S enantiomer, is a potent inhibitor of BET (Bromodomain and Extra-Terminal motif proteins).
价 格：￥电议型 号：T10517产 地：中国大陆
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T10481LBAY 73-6691；化合物 T10481L(R)-BAY 73-6691；(R)-BAY 73-6691
BAY 73-6691 is an inhibitor of brain penetrant PDE9A.
价 格：￥电议型 号：T10481L产 地：中国大陆
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T10481BAY 73-6691 racemate；化合物 T10481BAY 73-6691 racemate
BAY 73-6691 racemate is a phosphodiesterase 9 inhibitor.
价 格：￥电议型 号：T10481产 地：中国大陆
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T10480LBay 41-4109；化合物 T10480LBay 41-4109
BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV)(IC50 : 53 nM).
价 格：￥电议型 号：T10480L产 地：中国大陆
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T10480Bay 41-4109 (less active enantiomer)；化合物 T10480Bay 41-4109 (less active enantiomer)
Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109. BAY 41-4109 is a potent HBV inhibitor (IC50: 53 nM).
价 格：￥电议型 号：T10480产 地：中国大陆
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T10478BAY-Y 3118化合物 T10478BAY-Y3118|||BAY Y 3118|||BAY-Y 3118
BAY-Y 3118, a new chlorofluoroquinolone, has antimicrobial activity.
价 格：￥电议型 号：T10478产 地：中国大陆
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T10477BAY-985；化合物BAY-985BAY-985
BAY-985 is a potent, selective, and orally active ATP-competitive dual inhibitor of TBK1 and IKKε (IC50s: 2/30 and 2 nM for TBK1 (low/high ATP) and IKKε) with antitumor efficacy.
价 格：￥电议型 号：T10477产 地：中国大陆
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T10476BAY-899；化合物 T10476BAY-899
BAY-899 is an orally active and selective antagonist of the luteinizing hormone receptor (LH-R), exhibiting IC50 values of 185 nM and 46 nM for human LH (hLH) and rat LH (rLH) respectively. In vivo studies have demonstrated that BAY-899 effectively reduces sex hormone levels[1].
价 格：￥电议型 号：T10476产 地：中国大陆
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T10475BAY-784；化合物 T10475BAY-784
BAY-784 is a gonadotropin-releasing hormone receptor (GnRH-R) antagonist (IC50s: 21 and 24 nM for human and rat GnRH-R).
价 格：￥电议型 号：T10475产 地：中国大陆
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T10474BAY-7598；化合物 T10474BAY-7598
BAY-7598 is a potent, selective, and orally bioavailable MMP12 inhibitor (IC50s: 0.085, 0.67, and 1.1 nM for human/murine/rat MMP12).
价 格：￥电议型 号：T10474产 地：中国大陆
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T10473LBAY-677；化合物 T10473LBAY-677
BAY-677, serving as an inactive control for BAY-678, is distinguished by BAY-678´s capabilities as an orally bioavailable, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE), showcasing a high potency with an IC50 of 20 nM[1]. Furthermore, BAY-678 has been publicly nominated as a chemical probe by the Structural Genomics Consortium (SGC)[2].
价 格：￥电议型 号：T10473L产 地：中国大陆
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T10473BAY-678；化合物BAY-678BAY-678
BAY-678 is a human neutrophil elastase (HNE; IC50: 20 nM) inhibitor with oral bioactivity, potency and selectivity.BAY-678 is a chemical probe recommended by the Structural Genomics Consortium (SGC).
价 格：￥电议型 号：T10473产 地：中国大陆
