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T15239Epristeride;爱普列特SKF105657|||ONO-9302;SKF105657|||ONO-9302
Epristeride (ONO-9302) is an orally active, selective and non-competitive steroidal 5-α-reductase isoform 2 inhibitor that inhibits SR isoform 2.Episteride reduces prostate size and improves symptoms in men with BPH.Episteride induces atrophy and apoptosis of the ventral prostate in rats.
价 格:¥电议型 号:T15239产 地:中国大陆
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T15156Dodecaethylene glycol;化合物 T15156HO-PEG12-OH;HO-PEG12-OH
Dodecaethylene glycol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15156产 地:中国大陆
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T15056DB07107;化合物 T15056DB07107
DB07107 is a potent inhibitor of drug resistant T315I mutant Bcr-Abl tyrosine kinase and a potent Akt1 inhibitor (IC50: 360 nM).
价 格:¥电议型 号:T15056产 地:中国大陆
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T15002CP-105696;化合物CP-105696Pfizer 105696;Pfizer 105696
CP-105696 is a potent and selective leukotriene B4 (LTB4) receptor antagonist for the study of allograft rejection.
价 格:¥电议型 号:T15002产 地:中国大陆
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T14974Citenamide;西替酰胺Cytenamide|||AY-15613;Cytenamide|||AY-15613
Citenamide (AY-15613) has anticancer and anticonvulsant activity and is used in the study of neurological disorders because of its sleep-promoting properties.
价 格:¥电议型 号:T14974产 地:中国大陆
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T14956CHMFL-BTK-01;化合物 T14956CHMFL-BTK-01
CHMFL-BTK-01 is an irreversible inhibitor of BTK (IC50: 7 nM) and also potently inhibits BTK Y223 auto-phosphorylation.
价 格:¥电议型 号:T14956产 地:中国大陆
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T14925Cenisertib;化合物 T14925AS-703569|||R-763;AS-703569|||R-763
Cenisertib is A potent ATP-competitive multi-kinase inhibitor, showing inhibitory effects on the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5, FLT3, as well as kinase inhibitors of FER and its homolog. Cenisertib inhibits the growth of tumor mast cells (MCS) by inhibiting the activity of several different molecular targets. Cenisertib also inhibits tumor growth in pancreatic, breast, colon, ovarian and lung cancer and leukemia in xenograft models.
价 格:¥电议型 号:T14925产 地:中国大陆
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T14878CAY10566;化合物CAY10566CAY10566
CAY10566 shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells (IC50=7.9 nM or 6.8 nM). CAY10566 is a potent, orally bioavailable and selective stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50s of 4.5 and 26 nM in mouse and human enzymatic assays, respectively..
价 格:¥电议型 号:T14878产 地:中国大陆
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T14856Calcipotriol;卡泊三醇MC 903|||Calcipotriene;MC 903|||卡泊三醇|||Calcipotriene
Calcipotriol (MC 903) is a synthetic VitD3 analogue. Which has a high affinity for the vitamin D receptor.
价 格:¥电议型 号:T14856产 地:中国大陆
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T14756Boc-NH-PEG7-NH2;化合物Boc-NH-PEG7-NH2Boc-NH-PEG7-NH2
Boc-NH-PEG7-NH2 is a PEG-based PROTAC linker.
价 格:¥电议型 号:T14756产 地:中国大陆
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T14675BMS-564929;化合物 T14675BMS-564929
BMS-564929 is an agonist of androgen receptor (AR, Ki of 2.11±0.16 nM).
价 格:¥电议型 号:T14675产 地:中国大陆
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T14656Bis-propargyl-PEG3;化合物 T14656Bis-propargyl-PEG3
Bis-propargyl-PEG3 is a PEG-based PROTAC linker utilized for the synthesis of PROTACs. It is also employed in the synthesis of antiplasmodial zinc-dipicolylamine (ZnDPA) complexes[1] [2].
价 格:¥电议型 号:T14656产 地:中国大陆
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T14569BI8626;化合物 BI8626BI8626
BI8626 is a ubiquitin ligase HUWE1 inhibitor with protective effects against spontaneous desiccation syndrome in NOD/ShiLtj mice.BI8626 inhibits intracellular cholesterol and decreases the expression of phosphorylated ZAP-70, CD25, and other activation markers, and inhibits the proliferation of CD4 T-cells.
价 格:¥电议型 号:T14569产 地:中国大陆
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T14568BI8622;化合物 T14568BI8622
BI8622 is an ubiquitin ligase HUWE1 inhibitor (IC50: 3.1 μM).
价 格:¥电议型 号:T14568产 地:中国大陆
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T14567BI605906化合物 T14567BI605906|||BI 605906|||BI-605906
BI605906 is an inhibitor of IKKβ. When assayed at 0.1 mM ATP, the IC50 value is 380 nM.
价 格:¥电议型 号:T14567产 地:中国大陆
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T14566BI-9627;化合物 T14566BI-9627
BI-9627 is an inhibitor of sodium-hydrogen exchanger isoform 1 (NHE1) (EC50: 31 nM).
价 格:¥电议型 号:T14566产 地:中国大陆
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T14565BI-671800;化合物BI-671800AP-761|||Cmpd A;AP-761|||Cmpd A
BI-671800 (AP-761) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2). With IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has the potential to treat poorly controlled asthma[2].
价 格:¥电议型 号:T14565产 地:中国大陆
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T14561BI-3812;化合物BI-3812BI-3812
BI-3812 is an inhibitor of BCL6. Which inhibiting the BTB domain of BCL6 (IC50: 3 nM). BI-3812 also has antitumor activity.
价 格:¥电议型 号:T14561产 地:中国大陆
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T14560BI-2545;化合物 T14560BI-2545
BI-2545 is an autotaxin (ATX) inhibitor that significantly reduces LPA. For human ATX and rat ATX, the IC50s values are 2.2 nM and 3.4 nM , respectively.
价 格:¥电议型 号:T14560产 地:中国大陆
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T1456Doxorubicin阿霉素Hydroxydaunorubicin|||DOX|||阿霉素|||Adriamycin
Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.
价 格:¥电议型 号:T1456产 地:中国大陆