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  • T1564Cisplatin顺铂cis-Diaminodichloroplatinum|||CDDP|||顺铂

    Cisplatin (CDDP) is a DNA cross-linking agent. Cisplatin has antitumor activity and inhibits DNA synthesis by forming DNA adducts in cancer cells. Cisplatin also activates iron death and induces autophagy.

    价 格：￥电议型 号：T1564产 地：中国大陆

  • T15639K-756；化合物K-756K-756

    K-756 is a direct and selective inhibitor of tankyrase (TNKS), which inhibits the ADP-ribosylation activity of TNKS1 (IC50 = 31 nM) and TNKS2 (IC50 = 36 nM).

    价 格：￥电议型 号：T15639产 地：中国大陆

  • T15638K-252c；化合物 T15638K-252c

    K-252c is a staurosporine analog isolated from Nocardiopsis sp. and is a cell-permeable PKC inhibitor (IC50: 2.45 μM). K-252c also inhibits β-lactamase, chymotrypsin, and malate dehydrogenase. K-252c causes apoptosis in human chronic myelogenous leukemia cancer cells.

    价 格：￥电议型 号：T15638产 地：中国大陆

  • T15637K-252b；化合物 T15637K-252b

    K-252b, an indolocarbazole derived from the actinomycete Nocardiopsis, functions as a protein kinase C (PKC) inhibitor. It is effective in inhibiting extracellular kinases in cultured cells due to its inability to freely cross the cell membrane.

    价 格：￥电议型 号：T15637产 地：中国大陆

  • T15636K-252a；化合物 T15636Antibiotic K 252a|||Antibiotic SF 2370|||SF2370；Antibiotic K 252a|||Antibiotic SF 2

    K-252a is a staurosporine analog isolated from Nocardiopsis sp. soil fungi. K-252a inhibits protein kinase (IC50: 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively).

    价 格：￥电议型 号：T15636产 地：中国大陆

  • T15635JZP-430；化合物JZP-430JZP-430

    JZP-430 is an effective, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50: 44 nM). It also shows ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL).

    价 格：￥电议型 号：T15635产 地：中国大陆

  • T15634JYL 1421化合物JYL 1421SC 0030

    JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).

    价 格：￥电议型 号：T15634产 地：中国大陆

  • T15633JW74；化合物JW74JW74

    JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).

    价 格：￥电议型 号：T15633产 地：中国大陆

  • T15632JW 642；化合物JW 642JW 642

    JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL) (IC50: 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively).

    价 格：￥电议型 号：T15632产 地：中国大陆

  • T15631JTK-853；化合物 T15631JTK-853

    JTK-853 is a novel, non-nucleoside inhibitor of Hepatitis C Virus (HCV) polymerase. It also displays effective antiviral activity in HCV replicon cells (EC50s: 0.38 and 0.035 μM in genotype 1a H77 and 1b Con1 strains, respectively).

    价 格：￥电议型 号：T15631产 地：中国大陆

  • T15630Tilmacoxib；替马考昔RWJ57504|||JTP19605|||JTE522；RWJ57504|||JTP19605|||替马考昔|||JTE522

    Tilmacoxib is a highly selective, time-dependent, and irreversible inhibitor of human COX-2 ( IC50: 85 nM in an enzyme assay).

    价 格：￥电议型 号：T15630产 地：中国大陆

  • T1563Nifuroxazide；硝呋齐特Diarlidan|||Nifuroxazid|||Dicoferin；Diarlidan|||硝呋齐特|||Nifuroxazid|||Dicoferin|||硝呋

    Nifuroxazide (Diarlidan) is an orally available and cell-permeable nitrofuran-based antidiarrheal agent. It has the inhibitory effect against the activation of cellular STAT1/3/5 transcription.

    价 格：￥电议型 号：T1563产 地：中国大陆

  • T15629JTE-013；化合物JTE-013JTE-013

    JTE-013 is an effective and specific antagonist of S1P2. JTE-013 suppresses the specific binding of radiolabeled S1P to human and rat S1P2 (IC50s: 17 nM and 22 nM, respectively).

    价 格：￥电议型 号：T15629产 地：中国大陆

  • T15628JT010；化合物JT010JT010

    JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).

    价 格：￥电议型 号：T15628产 地：中国大陆

  • T15627(S)-JQ-35化合物 T15627TEN-010

    (S)-JQ-35 (TEN-010) is an inhibitor of the Bromodomain and Extra-Terminal (BET) family bromodomain-containing proteins. It has a potential antineoplastic activity.

    价 格：￥电议型 号：T15627产 地：中国大陆

  • T15626JPM-OEt；化合物 T15626JPM-OEt

    JPM-OEt is a broad spectrum cysteine cathepsin inhibitor with antitumor activity. JPM-OEt binds covalently in the active site and irreversibly inhibits the cysteine cathepsin family.

    价 格：￥电议型 号：T15626产 地：中国大陆

  • T15625JNJ4796；化合物 T15625JNJ4796

    JNJ4796 is an oral active fusion inhibitor of the influenza virus, by inhibiting hemagglutinin (HA)-mediated fusion to neutralizing the influenza A group 1 virus. JNJ4796 mimics the functionality of the broadly neutralizing antibodies (bnAbs).

    价 格：￥电议型 号：T15625产 地：中国大陆

  • T15624JNJ-64619178；化合物JNJ-64619178JNJ-64619178

    JNJ-64619178 is a selective, orally active, and pseudo-irreversible inhibitor of protein arginine methyltransferase 5 (IC50: 0.14 nM). It has effective activity In lung cancer.

    价 格：￥电议型 号：T15624产 地：中国大陆

  • T15623JNJ-61432059；化合物JNJ-61432059JNJ-61432059

    JNJ-61432059 is an oral active and selective negative modulator of TARP γ?8 Selective AMPAR(pIC50: 9.7).

    价 格：￥电议型 号：T15623产 地：中国大陆

  • T15622JNJ-54175446；化合物 JNJ-54175446JNJ-5446；JNJ-5446

    JNJ-54175446 (JNJ-5446) is a CNS-permeable and selective P2X7 receptor antagonist that attenuates the release of IL-1β/IL-18 from microglia, and may be used in the study of depression.

    价 格：￥电议型 号：T15622产 地：中国大陆

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