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T14556BI-167107;化合物 T14556BI-167107
BI-167107 is a high affinity, full agonist that binds to the β2 adrenergic receptor (β2AR, Kd of 84 pM).
价 格:¥电议型 号:T14556产 地:中国大陆
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T14456Azido-PEG5-alcohol;化合物 T14456Azido-PEG5-alcohol
Azido-PEG5-alcohol, a non-cleavable 5 unit polyethylene glycol (PEG) ADC linker, finds application in the synthesis of antibody-drug conjugates (ADCs)[1]. Additionally, it serves as a PEG-based PROTAC linker for the synthesis of PROTACs[2].
价 格:¥电议型 号:T14456产 地:中国大陆
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T14386AZD9567;化合物AZD9567Mizacorat;Mizacorat
AZD9567 is a potent and orally active and selective non-steroidal glucocorticoid receptor modulator (SGRM) with an IC50 value of 3.8 nM.It has demonstrated excellent efficacy in the Streptococcus cell wall (SCW) reactivation model of joint inflammation.
价 格:¥电议型 号:T14386产 地:中国大陆
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T14385AZD9056 hydrochloride;化合物AZD9056 hydrochlorideAZD9056 hydrochloride
AZD9056 hydrochloride is a P2X7 inhibitor,Which plays a significant role in pain-causing diseases and inflammation.
价 格:¥电议型 号:T14385产 地:中国大陆
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T14384AZD8797;化合物KAND567KAN-0440567|||KAND567;KAN-0440567|||KAND567
AZD8797 (KAND567) is an orally available, selective and potent human CX3CR1-converting antagonist with inhibitory effects on CX3CR1 and CXCR2, and potentially protects against SARS-CoV-2-induced neuronal damage, preventing worsening of nociceptive sensitization and microglial activation in a migraine model of rats following seizures.
价 格:¥电议型 号:T14384产 地:中国大陆
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T14356AVE-8134;化合物 T14356AVE-8134
AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively.
价 格:¥电议型 号:T14356产 地:中国大陆
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T1434Clarithromycin;克拉霉素A-56268;A-56268|||克拉霉素
Clarithromycin (A-56268) is a Macrolide Antimicrobial. The mechanism of action of clarithromycin is as a Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 3A Inhibitor, and P-Glycoprotein Inhibitor. The chemical classification of clarithromycin is Macrolides.
价 格:¥电议型 号:T1434产 地:中国大陆
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T1433Ritodrine hydrochloride;盐酸利托君DU21220|||Ritodrine HCl|||NSC 291565;DU21220|||盐酸利托君|||Ritodrine HCl|||
Ritodrine hydrochloride (NSC 291565) binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine hydrochloride (NSC 291565) is a phenethylamine derivative with tocolytic activity. Specifically, Ritodrine hydrochloride (NSC 291565) probably activates adenyl cyclase, thereby increasing production of cyclic adenosine monophosphate (cAMP), which in turn enhances the efflux of calcium from vasc
价 格:¥电议型 号:T1433产 地:中国大陆
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T14320ARL67156 trisodium salt;化合物 T14320ARL67156 trisodium salt
ARL 67156 is a weak competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively[1]. ARL67156 trisodium salt is an inhibitor of ecto-ATPase.
价 格:¥电议型 号:T14320产 地:中国大陆
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T14282Amuvatinib hydrochloride;化合物 T14282HPK 56 hydrochloride|||MP470 hydrochloride;HPK 56 hydrochloride||
Amuvatinib hydrochloride (MP470 hydrochloride) is an orally administred multi-targeted tyrosine kinase inhibitor that exhibits strong efficacy against mutant forms of c-Kit, PDGFRα, Flt3, c-Met, and c-Ret, while also acting as a suppressor of DNA repair by inhibiting the RAD51 protein, which is crucial for repairing DNA damage[1][2][3]. This dual mechanism contributes to its antineoplastic activity[4].
价 格:¥电议型 号:T14282产 地:中国大陆
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T14256Amino-Tri-(carboxyethoxymethyl)-methane;化合物 T14256Amino-Tri-(carboxyethoxymethyl)-methane
Amino-Tri-(carboxyethoxymethyl)-methane, an ADC linker and PROTAC linker, is a cleavable PEG compound utilized for the synthesis of antibody-drug conjugates (ADCs)[1] and PEG-based PROTACs[2].
价 格:¥电议型 号:T14256产 地:中国大陆
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T14156Ald-CH2-PEG3-azide;化合物 T14156Ald-CH2-PEG3-azide
Ald-CH2-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14156产 地:中国大陆
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T14115Acoziborole;化合物 T14115SCYX-7158|||AN5568;SCYX-7158|||AN5568
Acoziborole (SCYX-7158), a derivative of benzoxaborole, is a safe, effective and structurally novel antigen-worm agent for human African trypanosomiasis (HAT) studies. The MIC value of Acoziborole for T. b. brucei S427 was 0.6 ?g/mL.
价 格:¥电议型 号:T14115产 地:中国大陆
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T14090AC-55649;化合物AC-55649AC-55649
AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9.
价 格:¥电议型 号:T14090产 地:中国大陆
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T13956Uvarigrin;大花紫玉盘素Uvarigrin
Uvarigrin induces tumor multidrug resistance cell apoptosis and triggers Caspase-9 activation. Uvarigrin is isolated from the roots of Uvaria calamistrata.
价 格:¥电议型 号:T13956产 地:中国大陆
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T13918Tecalcet Hydrochloride;R-568 盐酸盐R-568 hydrochloride|||R-568 (hydrochloride);R-568 盐酸盐|||R-568 hydroc
Tecalcet Hydrochloride (R-568 hydrochloride) is an allosteric and positive modulator of the calcium-sensing receptor(CaSR). Tecalcet Hydrochloride increases the sensitivity to the activation of extracellular Ca2+.
价 格:¥电议型 号:T13918产 地:中国大陆
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T13856(R)-DNMDP;化合物 T13856(R)-DNMDP
(R)-DNMDP is a potent and selective agent of cancer cell cytotoxic.
价 格:¥电议型 号:T13856产 地:中国大陆
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T13787N-563;化合物 T13787N-563
N-563 promotes resistance to Candida albicans infection in mice
价 格:¥电议型 号:T13787产 地:中国大陆
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T13756Liquiritigenin-7-apiosylglucoside;芹糖新甘草苷Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranosi
Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranoside, a flavonoid extracted from Glycyrrhiza roots, exhibits lower cytotoxic effects on a variety of tumor and normal cells.
价 格:¥电议型 号:T13756产 地:中国大陆
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T13569Benin;化合物BeninButocine|||Butocin;Butocine|||Butocin
Benin (Butocine) is an effective cytostatic drug used for the treatment of generalized carcinoma of the breast.
价 格:¥电议型 号:T13569产 地:中国大陆