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T17388AM-Imidazole-PA-Boc;化合物 T17388AM-Imidazole-PA-Boc
AM-Imidazole-PA-Boc is an alkyl chain-derived PROTAC linker utilized for the synthesis of PROTAC IRAK4 degrader-1[1].
价 格:¥电议型 号:T17388产 地:中国大陆
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T17387Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP;化合物 T17387Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP|||Aloc D Ala Phe Lys(Alo
Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP is a cleavable linker utilized in the synthesis of antibody-drug conjugates (ADCs), which are innovative therapeutic agents that combine the targeting ability of antibodies with potent cytotoxic drugs.
价 格:¥电议型 号:T17387产 地:中国大陆
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T17386Alkyne-PEG4-SS-PEG4-alkyne;化合物 T17386Alkyne-PEG4-SS-PEG4-alkyne
Alkyne-PEG4-SS-PEG4-alkyne is an eight-unit polyethylene glycol (PEG) linker, designed for antibody-drug conjugates (ADCs) synthesis, that can be cleaved. This linker serves as a connection between the antibody and the drug, allowing for controlled release upon specific conditions [1].
价 格:¥电议型 号:T17386产 地:中国大陆
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T17371Ald-Ph-amido-PEG4-propargyl;化合物 T17371Ald-benzyl-amide-PEG4-propargyl;Ald-benzyl-amide-PEG4-propargy
Ald-Ph-amido-PEG4-propargyl is a non-cleavable 4-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker employed in ADC synthesis[1].
价 格:¥电议型 号:T17371产 地:中国大陆
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T17363β-Naphthoflavone-CH2-OH;化合物 T17363β-NF-CH2-OH;β-NF-CH2-OH
β-Naphthoflavone-CH2-OH (β-NF-CH2-OH) serves as an AhR E3 ligase ligand, forming chimeric molecules when connected to a protein ligand through a linker, resulting in PROTACs or SNIPERs (e.g., β-naphthoflavone-JQ1). These chimeric molecules recruit the AhR E3 ligase complex by incorporating AhR ligands. By inducing ubiquitination-mediated degradation, PROTACs effectively target and degrade cancer-promoting proteins [1].
价 格:¥电议型 号:T17363产 地:中国大陆
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T17362Acrylate-PEG-OH (MW 5000);化合物 T17362Acrylate-PEG-OH (MW 5000)
Acrylate-PEG-OH (MW 5000) is a Polyethylene Glycol (PEG)-based linker compound primarily utilized in PROTAC synthesis[1].
价 格:¥电议型 号:T17362产 地:中国大陆
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T17361Acrylate-PEG-OH (MW 3400);化合物 T17361Acrylate-PEG-OH (MW 3400)
Acrylate-PEG-OH (MW 3400) is a polyethylene glycol (PEG) derived PROTAC linker compound, which finds application in the synthesis of PROTACs[1].
价 格:¥电议型 号:T17361产 地:中国大陆
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T17360Acrylate-PEG-OH (MW 10000);化合物 T17360Acrylate-PEG-OH (MW 10000)
Acrylate-PEG-OH (MW 10000) is a Polyethylene Glycol (PEG) derived PROTAC linker utilized for synthesizing PROTACs[1].
价 格:¥电议型 号:T17360产 地:中国大陆
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T17359Acrylate-PEG-NH2 (MW 2000);化合物 T17359Acrylate-PEG-NH2 (MW 2000)
Acrylate-PEG-NH2 (MW 2000) is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker, employed for the synthesis of PROTACs [1].
价 格:¥电议型 号:T17359产 地:中国大陆
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T17358Acrylate-PEG-NH2 (MW 10000);化合物 T17358Acrylate-PEG-NH2 (MW 10000)
Acrylate-PEG-NH2 (MW 10000) is a polyethylene glycol (PEG)-based linker utilized in the synthesis of PROTACs[1].
价 格:¥电议型 号:T17358产 地:中国大陆
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T17351Acetylene-linker-Val-Cit-PABC-MMAE;化合物 T17351AcetylenelinkerValCitPABCMMAE|||LCB14-0602|||Acetylene
Acetylene-linker-Val-Cit-PABC-MMAE (LCB14-0602) is a drug-linker conjugate for antibody-drug conjugates (ADCs) that combines the ADC linker (Acetylene-linker-Val-Cit-PABC) with the potent tubulin inhibitor MMAE.
价 格:¥电议型 号:T17351产 地:中国大陆
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T17339(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin;化合物 T17339(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin
(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin is a polyethylene glycol (PEG)-based PROTAC linker utilized for the synthesis of PROTACs.
价 格:¥电议型 号:T17339产 地:中国大陆
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T17325Pomalidomide-PEG4-C-COOH;化合物Pomalidomide-PEG4-C-COOHCereblon Ligand -Linker Conjugates 1|||E3 Ligase
Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) is a synthesized E3 ligase ligand-linker conjugate that combines the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
价 格:¥电议型 号:T17325产 地:中国大陆
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T17281Z-Ile-Leu-aldehyde;化合物 T17281Z-IL-CHO|||GSI-XII|||γ-Secretase inhibitor XII;Z-IL-CHO|||GSI-XII|||γ-S
Z-Ile-Leu-aldehyde is an effective and competitive peptide aldehyde inhibitor of γ-secretase and notch.
价 格:¥电议型 号:T17281产 地:中国大陆
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T17063Tetrazine-Ph-PEG5-NHS ester;化合物 T17063Tetrazine-Ph-PEG5-NHS ester
Tetrazine-Ph-PEG5-NHS ester is a PEGylated N-hydroxysuccinimide (NHS) ester molecule that serves as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T17063产 地:中国大陆
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T17062Tetrazine-Ph-NHS ester;化合物 T17062Tetrazine-Ph-NHS ester
Tetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker commonly employed for synthesizing PROTACs[1].
价 格:¥电议型 号:T17062产 地:中国大陆
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T17061Tetrazine-Ph-acid;化合物 T17061Tetrazine-Ph-acid
Tetrazine-Ph-acid is an alkyl chain-derived PROTAC linker employed in PROTAC synthesis[1].
价 格:¥电议型 号:T17061产 地:中国大陆
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T17060Tetramethylrhodamine-5-iodoacetamide;化合物 T170605-TMRIA;5-TMRIA
Tetramethylrhodamine-5-iodoacetamide (5-TMRIA) is a thiol-selective reactive dye that is used to non-specifically label proteins via the cysteine residues and covalently label DNA fragments[1].
价 格:¥电议型 号:T17060产 地:中国大陆
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T17050Tetraethyl butane-?1,?4-?diylbis(phosphoramid?ate);化合物 T17050Tetraethyl butane-?1,?4-?diylbis(phosph
Tetraethyl butane- 1, 4- diylbis(phosphoramid ate) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
价 格:¥电议型 号:T17050产 地:中国大陆
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T17055-Amino-3H-imidazole-4-Carboxamide;4-氨基-5-咪唑甲酰胺4-Amino-5-imidazolecarboxamide|||AICA|||5-Aminoimidaz
5-Amino-3H-imidazole-4-Carboxamide (AICA) is an imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. Compounded with orotic acid, it is used to treat liver diseases.
价 格:¥电议型 号:T1705产 地:中国大陆