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T17047Tetrabenazine-d6丁苯那嗪 D6Ro 1-9569 D6|||丁苯那嗪 D6
Tetrabenazine D6 is the deuterium-labeled Tetrabenazine. Tetrabenazine is a VMAT-inhibitor used for the treatment of hyperkinetic movement disorder.
价 格：￥电议型 号：T17047产 地：中国大陆
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T1701H-ASP-PHE-OH；硫胺杂质BAspartyl-phenylalanine|||Demethylaspartame；Aspartyl-phenylalanine|||硫胺杂质B|||Demeth
H-ASP-PHE-OH (Aspartyl-phenylalanine) is used as pharmaceutical intermediates
价 格：￥电议型 号：T1701产 地：中国大陆
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T17002Tazemetostat hydrobromide；氢溴酸泰泽司他E-7438 hydrobromide|||EPZ-6438 hydrobromide；E-7438 hydrobromide|||氢
Tazemetostat hydrobromide (E-7438 hydrobromide) is a potent and selective EZH2 inhibitor. Tazemetostat hydrobromide inhibits the activity of human polycomb repressive complex 2 (PRC2)-containing wild-type EZH2 (Ki: 2.5 nM). Tazemetostat hydrobromide also inhibits EZH1 (IC50: 392 nM).
价 格：￥电议型 号：T17002产 地：中国大陆
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T16981TAMRA-Azide-PEG-biotin；化合物 T16981TAMRA-Azide-PEG-biotin
TAMRA-Azide-PEG-biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T16981产 地：中国大陆
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T16950Sudoxicam；舒多昔康4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide；舒多昔康||
Sudoxicam (4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) is a reversible antagonist of COX with anti-inflammatory, anti-edema, and antipyretic properties.
价 格：￥电议型 号：T16950产 地：中国大陆
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T1688Pregnanediol；孕二醇5Beta-Pregnane-3Alpha,20alpha-Diol|||Pregnandiol；5Beta-Pregnane-3Alpha,20alpha-Diol|
Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) is an inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol(5Beta-Pregnane-3Alpha,20alpha-Diol) has two hydroxyl groups, at 3-alpha and 20-alpha. It is detectable in URINE after OVULATION and is found in great quantities in the pregnancy urine.
价 格：￥电议型 号：T1688产 地：中国大陆
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T16858SBE-β-CD磺丁基-Β-环糊精磺丁基-Β-环糊精|||Sulfobutylether-β-Cyclodextrin
SBE-β-CD (Sulfobutylether-β-Cyclodextrin) is a β-cyclodextrin derivative with a sodium sulfonate salt separated from the lipophilic cavity by a butyl ether spacer group, or sulfobutylether. SBE-β-CD is widely used as a co-solvent in biological experiments.
价 格：￥电议型 号：T16858产 地：中国大陆
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T16693Pyrene-PEG5-alcohol；化合物 T16693Pyrene-PEG5-alcohol
Pyrene-PEG5-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T16693产 地：中国大陆
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T16692Pyrene-amido-PEG4-CH2CH2COOH；化合物 T16692Pyrene-amido-PEG4-CH2CH2COOH
Pyrene-amido-PEG4-CH2CH2COOH is a polyethylene glycol (PEG) derived linker, designed specifically for constructing proteolysis targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T16692产 地：中国大陆
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T16691Pyrene-amido-PEG4-azide；化合物 T16691Pyrene-amido-PEG4-azide
Pyrene-amido-PEG4-azide is a PEG-based proteolysis targeting chimera (PROTAC) linker utilized for synthesizing PROTACs [1].
价 格：￥电议型 号：T16691产 地：中国大陆
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T16516PG01；化合物PG01Phenylglycine-01；Phenylglycine-01
PG01 is a potent CFTR Cl-channel potentiator, effective against ΔF508 (Ka 0.3 μM), and also against E193K, G970R and G551D (CFTR mutants), with Kd values of 0.22 μM, 0.45 μM and 1.94 μM, respectively.PG01 increases ΔF508-CFTR Cl- currents upon addition of forskolin. F508-CFTR Cl-current upon addition of Forskolin, correcting the gating defect of CFTR mutants.
价 格：￥电议型 号：T16516产 地：中国大陆
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T16512PFE-360；化合物PFE-360PF-06685360；PF-06685360
PFE-360 (PF-06685360) is a potent and selective inhibitor of LRRK2 kinase (IC50: 2.3 nM in vivo).
价 格：￥电议型 号：T16512产 地：中国大陆
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T1645Ramipril；雷米普利HOE-498|||Tritace|||Altace|||Carasel；HOE-498|||Tritace|||雷米普利|||Altace|||Carasel
Ramipril (Altace) is a long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat.
价 格：￥电议型 号：T1645产 地：中国大陆
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T16277NCT-502；化合物NCT-502N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbo
NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-derived serine production and it has an IC50 of 3.7 μM against PHGDH.
价 格：￥电议型 号：T16277产 地：中国大陆
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T16237N-Me-N-bis-PEG4；化合物 T16237N-Me-N-bis-PEG4
N-Me-N-bis-PEG4 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T16237产 地：中国大陆
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T16236N-Me-N-bis(PEG2-propargyl)；化合物 T16236N-Me-N-bis(PEG2-propargyl)
N-Me-N-bis(PEG2-propargyl) is a PEG-based linker employed for the synthesis of PROTACs[1].
价 格：￥电议型 号：T16236产 地：中国大陆
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T1616Cefotiam hydrochloride；盐酸头孢替安Pansporin|||SCE-963 hydrochloride|||Pansporine|||Cefotiam dihydrochlori
Cefotiam hydrochloride (SCE-963 hydrochloride) is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.
价 格：￥电议型 号：T1616产 地：中国大陆
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T16145MS-444化合物 T16145BE-34776
MS-444 suppresses the activity of purified smooth muscle myosin light chain kinase (MLCK) (IC50: 10 μM).
价 格：￥电议型 号：T16145产 地：中国大陆
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T16114Pavinetant；化合物 PavinetantMLE-4901|||AZD4901|||AZD2624；MLE-4901|||AZD4901|||AZD2624
Pavinetant (MLE-4901) is an orally available neurokinin-3 receptor (NK3R) antagonist used to improve menopausal symptoms.
价 格：￥电议型 号：T16114产 地：中国大陆
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T16109ML402；化合物ML402ZINC3671497|||N-[2-(4-chloro-2-methylphenoxy)ethyl]thiophene-2-carboxamide；ZINC3671497
ML402 (ZINC3671497) is an activator of TREK-1 and TREK-2 with EC50s of 13.7 μM and 5.9 μM.
价 格：￥电议型 号：T16109产 地：中国大陆
