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T73599TSPO ligand-1;TSPO配体1TSPO ligand-1
TSPO ligand-1 has affinity for peripheral and central benzodiazepine receptors.TSPO ligand-1 is an AUTAC4-binding protein in the transmembrane domain of the outer mitochondrial membrane, which induces mitochondrial autophagy and promotes intracellular mitochondrial regeneration.TSPO ligand-1 is involved in intracellular cholesterol transport, and can be used as a biomarker for brain injury and neurodegeneration. TSPO ligand-1 is involved in intracellular cholesterol transport and can be used as
价 格:¥电议型 号:T73599产 地:中国大陆
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T72985Masofaniten;化合物 MasofanitenAndrogen receptor-IN-2;Androgen receptor-IN-2
Masofaniten (Androgen receptor-IN-2), a potent, orally active inhibitor of the androgen receptor, demonstrates significant antitumor activity against prostate cancer.
价 格:¥电议型 号:T72985产 地:中国大陆
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T72804Isograndifoliol;化合物 IsograndifoliolIsograndifoliol
Isograndifoliol is a chemical compound that acts as a selective inhibitor of butyrylcholinesterase (BChE) with an IC50 value of 0.9 μM and exhibits moderate inhibition of acetylcholinesterase (AChE) with an IC50 value of 342.9 μM. Additionally, it demonstrates vasorelaxant and anti-tumor effects. This compound is utilized in research targeting dementia associated with neurodegenerative diseases.
价 格:¥电议型 号:T72804产 地:中国大陆
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T72580Isoandrographolide;化合物 IsoandrographolideIsoandrographolide
Isoandrographolide, a compound known for its cell differentiation-inducing and hepatoprotective effects, also inhibits NLRP3 inflammasome activation and mitigates silicosis in mice.
价 格:¥电议型 号:T72580产 地:中国大陆
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T72318Trandolaprilate hydrate;化合物 Trandolaprilate hydrateTrandolaprilat hydrate ; RU 44403 hydrate|||RU 4
Trandolaprilate hydrate, the main bioactive metabolite of Trandolapril and a potent angiotensin-converting enzyme (ACE) inhibitor, exhibits high lipophilicity and partially inhibits angiotensin-I-mediated c-fos induction.
价 格:¥电议型 号:T72318产 地:中国大陆
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T72279Flurandrenolone Acetate;化合物 Flurandrenolone AcetateFlurandrenolone Acetate
Flurandrenolone Acetate, a synthetic glucocorticoid steroid derivative of Flurandrenolide, is utilized in researching skin disorders including eczema and psoriasis [1].
价 格:¥电议型 号:T72279产 地:中国大陆
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T72018MAO-B ligand-1;化合物 MAO-B ligand-1MAO-B ligand-1
MAO-B ligand-1 is a selective MAO-B inhibitor.
价 格:¥电议型 号:T72018产 地:中国大陆
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T72013Epigenetic Multiple Ligand;化合物 Epigenetic Multiple LigandEpigenetic Multiple Ligand
Epigenetic Multiple Ligand is a cell-permeable inhibitor of substrate processing by several chromatin-associated enzymes, including SIRT1/2, H3/SET7, H3/p300/CBP, H4/RmtA, PABP1/CARM1, and H4/PRMT1. It acts by inducing either apoptosis or granulocytic differentiation.
价 格:¥电议型 号:T72013产 地:中国大陆
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T718515-trans-Prostaglandin E2;化合物 5-trans-Prostaglandin E25-trans-Prostaglandin E2
5-trans-Prostaglandin E2 accelerates fibrinolysis by enhancing plasminogen activation mediated by tissue-type plasminogen activator. It also inhibits platelet aggregation in human PRP.
价 格:¥电议型 号:T71851产 地:中国大陆
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T71657Evandamine;化合物 EvandamineEvandamine
Evandamine is a Lipooxygenase Inhibitor
价 格:¥电议型 号:T71657产 地:中国大陆
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T71405Domitroban;化合物 DomitrobanDomitroban
Domitroban, also known as S-145, is a thromboxane (Tx) A2-receptor antagonist with partial agonistic activity in vascular smooth muscle.
价 格:¥电议型 号:T71405产 地:中国大陆
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T71402Nicorandil-d4;化合物 Nicorandil-d4Nicorandil-d4
Nicorandil-d4 is intended for use as an internal standard for the quantification of nicorandil by GC- or LC-MS. Nicorandil is an activator of sulfonylurea receptor 2B (SUR2B) linked to ATP-sensitive potassium channel Kir6.2 (EC50 = ~10 ?M) and a nitric oxide (NO) donor. It is selective for SUR2B/Kir6.2 over the SUR2A/Kir6.2 channel (EC50 = >500 ?M). Nicorandil activates soluble guanylate cyclase in a cell-free assay and relaxes partially depolarized isolated bovine coronary artery strips (EC50 =
价 格:¥电议型 号:T71402产 地:中国大陆
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T71168Epetraborole R-Mandelate;化合物 Epetraborole R-MandelateEpetraborole R-Mandelate
Epetraborole R-Mandelate is a potent and selective leucyl-tRNA synthetase inhibitor.
价 格:¥电议型 号:T71168产 地:中国大陆
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T71053AHR-5333 mandelate;化合物 AHR-5333 mandelateAHR-5333 mandelate
AHR-5333 mandelate is an anti-allergy compound which has been shown to protect against antigen-induced anaphylactic collapse and ascaris antigen-induced skin hypersensitivity. AHR-5333 mandelate has also been shown to inhibit 5-HETE, LTB4 and LTC4 synthesis.
价 格:¥电议型 号:T71053产 地:中国大陆
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T70784Decarbonyl zolmitriptan;化合物 Decarbonyl zolmitriptanDecarbonyl zolmitriptan
is a compound related to Zolmitriptan (Z639000), which is Serotonin 5HTID-receptor agonist.
价 格:¥电议型 号:T70784产 地:中国大陆
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T70672Dexefaroxan;化合物 DexefaroxanDexefaroxan
Dexefaroxan is an alpha(2)-adrenoceptor antagonist.
价 格:¥电议型 号:T70672产 地:中国大陆
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T70581CY208-243 Mandelate;化合物 CY208-243 MandelateCY208-243 Mandelate
CY208-243 is a D1 agonist. CY208-243 attenuates the pattern electroretinogram to low spatial frequency stimuli in the monkey. CY208-243 stimulates adenylate cyclase in rat striatal homogenates with an EC50 of 125 nM. CY208,243 was superior in improving the strength of neuronal outcome sensitivity to the working memory-related choice behavior in the T-maze.
价 格:¥电议型 号:T70581产 地:中国大陆
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T70384Dolispan;化合物 DolispanDolispan
Dolispan is a Histamine H1 Antagonist.
价 格:¥电议型 号:T70384产 地:中国大陆
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T70277Cynandione A;化合物 Cynandione ACynandione A
Cynandione A, an acetophenone derived from Cynanchum wilfordii, has anti-inflammatory activity and significantly reduces pro-inflammatory cytokine overexpression via macrophage α7 nAChR activation and subsequent IL-10 expression.
价 格:¥电议型 号:T70277产 地:中国大陆
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T6S1917Schisandrol B;五味子醇乙Gomisin A|||TJN-101|||Besigomsin|||Gamma-Schisandrin|||Schizandrol B|||Wuweizi al
1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has anti-inflammatory property, potentially result from the inhibition of COX-2, iNOS, IL-6, TNF-α and NO through the down-regulation of RIP2 and NF-κB activation. 3. Schisandrol B induces marked protective effects against hepatic and renal injury induced by CCl(4) exposure through di
价 格:¥电议型 号:T6S1917产 地:中国大陆