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T62992Trandolapril hydrochloride;化合物 Trandolapril hydrochlorideTrandolapril hydrochloride
Trandolapril (RU44570) hydrochloride is a non-mercapto precursor compound that is hydrolysed to active diacetyl (Trandolapril hydrochlorideat). Trandolapril hydrochloride has been studied in hypertension and congestive heart failure and myocardial infarction.
价 格:¥电议型 号:T62992产 地:中国大陆
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T62899Tau-aggregation and neuroinflammation-IN-1;Tau蛋白聚集体和神经炎症抑制剂1Tau-aggregation and neuroinflammation-IN
Tau-aggregation and neuroinflammation-IN-1 is a potent inhibitor of tau protein aggregates, showing significant inhibitory activity against AcPHF6 and full-length tau protein aggregates. Tau-aggregation and neuroinflammation-IN-1 has anti-inflammatory activity and reduces NO release.Tau-aggregation and neuroinflammation-IN-1 has low cytotoxicity against LSP-stimulated BV2 cells.Tau-aggregation and neuroinflammation-IN-1 reverses okadaic acid-induced memory impairment in rats.
价 格:¥电议型 号:T62899产 地:中国大陆
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T62870FABPs ligand 6;化合物 FABPs ligand 6FABPs ligand 6
FABPs ligand 6 (MF6) is an inhibitor of FABP5 (Kd: 874 nM) and FABP7 (Kd: 20 nM), which can be used in the study of multiple sclerosis.
价 格:¥电议型 号:T62870产 地:中国大陆
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T62528Dopamine D3 receptor ligand-1;化合物 Dopamine D3?receptor ligand-1Dopamine D3 receptor ligand-1
Dopamine D 3 receptor ligand is a potent, selective, high-affinity dopamine D3 receptor ligand that is 89 times more selective for D3 (Ki: 8 nM) than D2 (Ki: 715 nM).
价 格:¥电议型 号:T62528产 地:中国大陆
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T62215Tandospirone hydrochloride;化合物 Tandospirone hydrochlorideTandospirone hydrochloride
Tandospirone (SM-3997) hydrochloride is a potent, selective 5-HT1A receptor partial agonist (Ki: 27 nM) that exhibits anxiolytic and antidepressant activity. tandospirone hydrochloride can be used to study central nervous system disorders and their underlying mechanisms.
价 格:¥电议型 号:T62215产 地:中国大陆
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T62141RBP4 ligand-1;化合物 RBP4 ligand-1RBP4 ligand-1
RBP4 ligand-1 is a non-retinoid ligand for retinol-binding protein 4 (RBP4). hRBP4SPAIC50 and RBP4-TTR FRET IC50 values were 0.23±0.11 and 0.13±0.12 μM for the radioligand binding assay and FRET assay, respectively. 0.12 μM.
价 格:¥电议型 号:T62141产 地:中国大陆
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T61825EED ligand 1;化合物 EED ligand 1EED ligand 1
EED ligand 1 is a highly versatile, potent, and effective inhibitor that specifically targets the EED subunit of the polycomb repressive complex 2 (PRC2) methyltransferase.
价 格:¥电议型 号:T61825产 地:中国大陆
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T615155-HT7 receptor ligand 1;化合物 5-HT7 receptor ligand 15-HT7 receptor ligand 1
5-HT7 receptor ligand 1 (Compound 5c) is a potent ligand for the 5-HT7 receptor, with a K i value of 8 nM. The compound demonstrates non-hepatotoxic properties and displays moderate potential for drug-drug interactions with substrates of CYP3A4 or CYP2D6 enzymes [1].
价 格:¥电议型 号:T61515产 地:中国大陆
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T612205-HT6/5-HT2A receptor ligand-2;化合物 5-HT6/5-HT2A receptor ligand-25-HT6/5-HT2A receptor ligand-2
Compound 42, a 5-HT6/5-HT2A receptor ligand-2, serves as a dual antagonist for the 5-HT6 and 5-HT2A receptors with Ki values of 25 nM and 32 nM, respectively. This brain-penetrant compound exhibits pro-cognitive properties [1].
价 格:¥电议型 号:T61220产 地:中国大陆
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T612075-HT6/5-HT2A receptor ligand-1;化合物 5-HT6/5-HT2A receptor ligand-15-HT6/5-HT2A receptor ligand-1
5-HT6/5-HT2A receptor ligand-1 (compound 33) is a dual antagonist for the 5-HT6 and 5-HT2A receptors. It exhibits a K i value of 2 nM and 11 nM for the respective receptors. This compound holds promise for research in neurological and psychiatric disorders [1].
价 格:¥电议型 号:T61207产 地:中国大陆
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T60988Androgen receptor antagonist 4;化合物 Androgen receptor antagonist 4Androgen receptor antagonist 4
Androgen receptor antagonist 4 (Compound AT2) has anticancer activities. Androgen receptor antagonist 4 potently antagonizes the activity of AR transcriptional, inhibits downstream target gene of AR, and blocks the DHT-induced nuclear translocation of AR. Androgen receptor antagonist 4 is an antagonist of androgen receptor (AR) (IC 50 = 0.15 μM) [1].
价 格:¥电议型 号:T60988产 地:中国大陆
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T60987Androgen receptor antagonist 3;化合物 Androgen receptor antagonist 3Androgen receptor antagonist 3
Androgen receptor antagonist 3 (Compound C18) has anticancer activities that is an antagonist of androgen receptor (AR) (IC 50 = 2.4 μM) [1].
价 格:¥电议型 号:T60987产 地:中国大陆
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T60965Anticandidal agent-1;化合物 Anticandidal agent-1Anticandidal agent-1
Anticandidal agent-1 (compound c2) is a potent and broad-spectrum anticandidal agent that inhibits biofilm through blocking hyphal elongation and filamentation. Anticandidal agent-1 exhibits anticandidal activity against C. glabrata and C. albicans, with MIC 50 values of 13.51 and 8.65 μg/mL, respectively [1].
价 格:¥电议型 号:T60965产 地:中国大陆
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T60728M1 ligand 1;化合物 M1 ligand 1M1 ligand 1
M1 ligand 1 (compound 3b-b) is a N-desmethyl congener of arecoline derivative that is a muscarinic acetylcholine receptor M1 ligand. M1 ligand 1 is able to be used as PET (positron emission tomography) radiotracer [1].
价 格:¥电议型 号:T60728产 地:中国大陆
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T60722Prohibitin ligand 1;化合物 Prohibitin ligand 1Prohibitin ligand 1
Prohibitin ligand 1 (Compound 22i) is a cardioprotectant prohibitin ligand that exhibits in vitro cardioprotectant activities at nanomolar concentrations. Prohibitin ligand 1 induces the pro-survival factor STAT3 phosphorylation [1].
价 格:¥电议型 号:T60722产 地:中国大陆
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T60279GID4 Ligand 2;化合物 GID4 Ligand 2GID4 Ligand 2
GID4 Ligand 2 (compound 67) is a selective binder for GID4 with IC50 of 18.9 μM and Kd of 17 μM. GID4 Ligand 2 can be used for the synthesis of PROTACs [1].
价 格:¥电议型 号:T60279产 地:中国大陆
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T60251GID4 Ligand 3;化合物 GID4 Ligand 3GID4 Ligand 3
GID4 Ligand 3 (compound 16) is a binder of GID4 with an Kd value of 110 μM in vitro and an IC 50 value of 148.5 μM. GID4 Ligand 3 can be used in the relevant research of cereblon(CRBN) and Von Hippel-Lindau(VHL) [1].
价 格:¥电议型 号:T60251产 地:中国大陆
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T60015TSPO ligand-2u00A0;化合物 Carbonic acidCarbonic acid;Carbonic acid
TSPO ligand-2 (Carbonic acid) is a ligand of AUTAC1 which contains a p-fluorobenzylguanine and a Fumagillol moiety.
价 格:¥电议型 号:T60015产 地:中国大陆
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T5S2139Epimedin A1;朝藿定A1Hexandraside F;朝藿定A1|||Hexandraside F
Epimedin A1 (Hexandraside F)(Hexandraside F) is a flavonoid extracted from Herba Epimedii which is one of commonly used Chinese medicines.
价 格:¥电议型 号:T5S2139产 地:中国大陆
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T5S1923Schisandrin C;五味子丙素Schizandrin-C|||Wuweizisu-C;五味子丙素|||Schizandrin-C|||Wuweizisu-C
Schisandrin C (Wuweizisu-C) is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells.
价 格:¥电议型 号:T5S1923产 地:中国大陆