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T1568Amoxapine阿莫沙平阿莫沙平|||CL-67772
Amoxapine (CL-67772) exerts its antidepressant effect by inhibiting the re-uptake of norepinephrine and, to a lesser degree, of serotonin, at adrenergic nerve endings and blocks the response of dopamine receptors to dopamine. Amoxapine is a tricyclic antidepressant of the dibenzoxazepine class. This drug is used to treat symptoms of depression and may cause tardive dyskinesia. Amoxapine also binds to alpha-adrenergic, histaminergic, and cholinergic receptors which accounts for many of the side e
价 格:¥电议型 号:T1568产 地:中国大陆
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T15677KY1220;化合物KY1220KY1220
KY1220 destabilizes both β-catenin and Ras by targeting the Wnt/β-catenin pathway. It has an IC50 of 2.1 μM in HEK293 reporter cells.
价 格:¥电议型 号:T15677产 地:中国大陆
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T15641K777;化合物K777APC-3316;APC-3316
K777 is a potent, orally active and irreversible inhibitor of cysteine protease. K777 is a potent CYP3A4 inhibitor (IC50= 60 nM). K777 is also a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 irreversibly inhibits Cruzain, which is the major cysteine protease of Trypansoma cruzi, and cathepsins B and L. K777 targets cathepsin-mediated cell entry and wxibits a broad-spectrum antiviral activity. K777 inhibits EBOV and SARS-CoV pseudovirus entry with IC50 values of 0.87
价 格:¥电议型 号:T15641产 地:中国大陆
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T15619JNJ-46778212;化合物 JNJ-46778212VU 0409551;VU 0409551
JNJ-46778212 (VU 0409551) is a selective and potent mGlu5 allosteric modulator (EC50: 260 nM) for the study of neurodissection.
价 格:¥电议型 号:T15619产 地:中国大陆
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T15617JNJ-38877618;化合物JNJ-38877618OMO-1;OMO-1
JNJ-38877618 (OMO-1) is an effective and highly selective inhibitor of Met kinase (IC50s: 2 and 3 nM for wild type and mutant Met, respectively).
价 格:¥电议型 号:T15617产 地:中国大陆
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T15577Indobufen吲哚布芬Ibustrin|||吲哚布芬
Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes.
价 格:¥电议型 号:T15577产 地:中国大陆
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T15477Hexaminolevulinate hydrochloride;5-氨基酮戊酸己酯盐酸盐Hexyl 5-aminolevulinate hydrochloride|||5-Aminolevulini
Hexaminolevulinate hydrochloride (P-1206) has approved for cystoscopic detection of papillary bladder cancer and it also is a fluorescent agent.
价 格:¥电议型 号:T15477产 地:中国大陆
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T15382GI 181771;化合物GI 181771GI 181771
GI 181771 is an agonist of the cholecystokinin 1 receptor. GI 181771 can be used in studies about obesity.
价 格:¥电议型 号:T15382产 地:中国大陆
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T15377Ravoxertinib hydrochloride化合物 T15377GDC-0994 (hydrochloride)
Ravoxertinib hydrochloride is an orally bioavailable and selective inhibitor for ERK kinase activity (IC50: 6.1 nM and 3.1 nM for ERK1 and ERK2, respectively).
价 格:¥电议型 号:T15377产 地:中国大陆
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T15375Inavolisib;化合物 InavolisibGDC-0077|||RG6114;GDC-0077|||RG6114
Inavolisib (GDC-0077) is an orally available and selective inhibitor of PI3Kα (IC50=0.038 nM). Inavolisib is more selective for mutant versus wild-type PI3Kα. Inavolisib exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3.
价 格:¥电议型 号:T15375产 地:中国大陆
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T15337Forodesine呋咯地辛Immucillin-H|||BCX-1777
Forodesine (BCX-1777) is an orally active and potent purine nucleoside phosphorylase (PNP) inhibitor, a new purine nucleoside analog, inhibitor of human lymphocyte proliferation, induces apoptosis in leukemic cells by increasing dGTP levels, and may be useful in the study of cutaneous T-cell lymphomas.
价 格:¥电议型 号:T15337产 地:中国大陆
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T15277Fervenulin;热诚菌素Fervenulin
Fervenulin is isolated from a nematicidal actinomycete Streptomyces sp. CMU-MH021 has nematicidal activity. CMU-MH021 inhibits egg hatch(MICs: 30 μg/mL) and J2 mortality(MICs: 120 μg/mL) of M. incognita.
价 格:¥电议型 号:T15277产 地:中国大陆
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T15144DMP 777;化合物 T15144L-694458;L-694458
DMP 777 is an orally active inhibitor of human leukocyte elastase.
价 格:¥电议型 号:T15144产 地:中国大陆
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T15077DBCO-Sulfo-Link-biotin;化合物 T15077DBCO-Sulfo-Link-biotin
DBCO-Sulfo-Link-biotin is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs) [1].
价 格:¥电议型 号:T15077产 地:中国大陆
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T15045D77;化合物 T15045D77
D77 is anti-HIV-1 inhibitor. D77 inhibits HIV-1(IIIB) replication by EC50 value of 23.8 μg/ml in MT-4 cell (5.03 μg/ml for C8166 cells).
价 格:¥电议型 号:T15045产 地:中国大陆
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T14986CMI977;化合物 T14986LDP977;LDP977
CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).
价 格:¥电议型 号:T14986产 地:中国大陆
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T14977CL-275838;化合物 T14977CL-275838
CL-275838 is a compound of memory-enhancing with potent antidepressant activities.
价 格:¥电议型 号:T14977产 地:中国大陆
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T14966Cimetropium Bromide;西托溴铵DA-3177;西托溴铵|||DA-3177
Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.
价 格:¥电议型 号:T14966产 地:中国大陆
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T14941CGP37157;CGP371577-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepine-2(3H)-one;7-Chloro-5-(2
CGP37157 (7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepine-2(3H)-one) is a Na+/Ca2+ exchanger inhibitor, inhibits Na+-induced Ca2+ release from mitochondria in guinea pig heart with IC50 of 0.8 μM.
价 格:¥电议型 号:T14941产 地:中国大陆
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T14934Cethromycin;化合物 T14934Abbott-195773|||ABT-773|||A-195773;Abbott-195773|||ABT-773|||A-195773
Cethromycin (ABT-773) is an antibiotic of ketolide.
价 格:¥电议型 号:T14934产 地:中国大陆