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T13049LSynucleozid hydrochloride (502139-01-7 free base);化合物 T13049LSynucleozid hydrochloride|||NSC 377363
Synucleozid hydrochloride is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.
价 格:¥电议型 号:T13049L产 地:中国大陆
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T13049Synucleozid;化合物 T13049NSC 377363;NSC 377363
Synucleozid is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.
价 格:¥电议型 号:T13049产 地:中国大陆
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T13017STL127705;化合物STL127705Compound L|||7-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-fluorophenyl)pyrimid
STL127705 (Compound L) is a potent Ku 70/80 heterodimer protein inhibitor and inhibits Ku70/80-DNA interaction with IC50 of 3.5 μM. STL127705 inhibits the activation of Ku-dependent DNA-PKCS kinase with IC50 of 2.5 μM.
价 格:¥电议型 号:T13017产 地:中国大陆
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T12977Soraprazan;化合物 T12977BYK61359;BYK61359
Soraprazan is a reversible, and fast-acting gastric H+/K+ ATPase inhibitor.
价 格:¥电议型 号:T12977产 地:中国大陆
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T12955Sofosbuvir D6;化合物 T12955PSI-7977 D6|||GS-7977 D6;PSI-7977 D6|||GS-7977 D6
Sofosbuvir D6 is the deuterium labeled Sofosbuvir. Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
价 格:¥电议型 号:T12955产 地:中国大陆
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T12954Sofosbuvir 13CD3;化合物 T12954GS-7977 13CD3|||PSI-7977 13CD3;GS-7977 13CD3|||PSI-7977 13CD3
Sofosbuvir 13CD3 is the deuterium labeled Sofosbuvir. Sofosbuvir is an active HCV RNA replication inhibitor in the HCV replicon assay, with potent anti-hepatitis C virus (HCV) activity.
价 格:¥电议型 号:T12954产 地:中国大陆
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T12944SNT-207707;化合物 T12944SNT-207707
SNT-207707 is a potent, selective and orally active antagonist of melanocortin MC-4 receptor(IC50 of 8 nM (binding) and 5 nM (function) on the MC-4 receptor).
价 格:¥电议型 号:T12944产 地:中国大陆
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T12877LSeltorexant;化合物SeltorexantJNJ-42847922;JNJ-42847922
Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain. Seltorexant is a high-affinity and selective orexin-2 receptor antagonist (pKi: 8.0 and 8.1 for human and rat OX2R).
价 格:¥电议型 号:T12877L产 地:中国大陆
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T12877Seltorexant hydrochloride;化合物 T12877JNJ-42847922 hydrochloride;JNJ-42847922 hydrochloride
Seltorexant hydrochloride is a selective, orally active and high-affinity antagonist of OX2R with pKi values of 8.0 and 8.1 for human and rat OX2R.
价 格:¥电议型 号:T12877产 地:中国大陆
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T12861LSB-277011 dihydrochloride;化合物 T12861LSB-277011A dihydrochloride;SB-277011A dihydrochloride
SB-277011 dihydrochloride is a potent, selective, orally bioavailable and brain penetrate antagonist of dopamine D3 receptor(pKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively).
价 格:¥电议型 号:T12861L产 地:中国大陆
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T12861SB-277011;化合物SB-277011SB-277011A;SB-277011A
SB-277011 (SB-277011A) is a specific antagonist of the dopamine D3 receptor with pKi values of 8.0, 6.0, 5.0, and <5.2 for D3 receptor, D2 receptor, 5-HT1D, and 5-HT1B respectively.
价 格:¥电议型 号:T12861产 地:中国大陆
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T12853SBI-477;化合物SBI-477SBI-477
SBI-477 is a chemical probe stimulated insulin signaling by deactivating the transcription factor MondoA. SBI-477 coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes.
价 格:¥电议型 号:T12853产 地:中国大陆
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T12806(S)-Mirtazapine D3;化合物 T12806(S)-Org3770 D3|||(S)-6-Azamianserin D3;(S)-Org3770 D3|||(S)-6-Azamianse
(S)-Mirtazapine D3 is a deuterium labeled (S)-Mirtazapine. (S)-Mirtazapine is a stereoselective antagonist of 5-HT2 receptor. (S)-Mirtazapine is metabolized by CYP2D6 and CYP1A2.
价 格:¥电议型 号:T12806产 地:中国大陆
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T12779Ru-32514;化合物 Ru-32514Ru-32514
Ru-32514 is a benzodiazepine receptor agonist that partially reverses stress-induced arousal in mice and is used in the study of neurological disorders.
价 格:¥电议型 号:T12779产 地:中国大陆
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T12778LRTI-13951-33;化合物 T12778LRTI-13951-33
RTI-13951-33 is an effective and brain-penetrant GPR88 agonist (EC50: 25 nM, in GPR88 cAMP functional assay).
价 格:¥电议型 号:T12778L产 地:中国大陆
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T12778RTI-13951-33 hydrochloride;化合物 T12778RTI-13951-33 hydrochloride (2244884-08-8 free base);RTI-13951-3
RTI-13951-33 hydrochloride is a potent, selective, and brain-penetrant GPR88 agonist. RTI-13951-33 hydrochloride exhibited an EC 50 of 25 nM in vitro cAMP functional assay. RTI-13951-33 hydrochloride significantly reduces alcohol reinforcement and intake behaviors in rats [1].
价 格:¥电议型 号:T12778产 地:中国大陆
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T12777RTC-5;化合物RTC-5TRC-382;TRC-382
RTC-5 (TRC-382) is a phenothiazine compound that has been specifically enhanced for its potent anti-cancer properties. It exhibits considerable effectiveness against an EGFR-driven cancer xenograft model. The mechanism behind its efficacy can be attributed to the simultaneous inhibition of PI3K-AKT and RAS-ERK signaling pathways.
价 格:¥电议型 号:T12777产 地:中国大陆
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T12776LReal Thiol;化合物 T12776LReal Thiol
Real Thiol, a reversible reaction-based fluorescent probe, can quantitatively monitor the real-time glutathione dynamics in living cells.
价 格:¥电议型 号:T12776L产 地:中国大陆
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T12776RT-AM;化合物 T12776RT-AM
RT-AM is a pro-drug real thiol. Real Thiol is a reversible reaction-based fluorescent probe.
价 格:¥电议型 号:T12776产 地:中国大陆
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T12775RSV604 (R enantiomer);化合物 T12775RSV604 R enantiomer;RSV604 R enantiomer
RSV604 R enantiomer is the R-enantiomer of RSV604. RSV604 is a respiratory syncytial virus (RSV) replication inhibitor.
价 格:¥电议型 号:T12775产 地:中国大陆