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T5193Danirixin;化合物DanirixinGSK1325756;GSK1325756
Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).
价 格:¥电议型 号:T5193产 地:中国大陆
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T5097Ezatiostat;化合物EzatiostatTER199(free base)|||TLK199;TER199(free base)|||TLK199
Ezatiostat (TER199(free base)) is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity.
价 格:¥电议型 号:T5097产 地:中国大陆
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T5093Pim1/AKK1-IN-1;化合物Pim1/AKK1-IN-1LKB1/AAK1 dual inhibitor|||MDK-2275;LKB1/AAK1 dual inhibitor|||MDK-2
Pim1/AKK1-IN-1 (LKB1/AAK1 dual inhibitor) is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.
价 格:¥电议型 号:T5093产 地:中国大陆
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T4S1499Ginsenoside Rk1人参皂苷人参皂苷RK1|||人参皂苷
Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures. Ginsenoside Rk1 has an anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB. It also has an anti-tumor effect.
价 格:¥电议型 号:T4S1499产 地:中国大陆
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T4459PK11000;化合物PK11000PK11000
PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.
价 格:¥电议型 号:T4459产 地:中国大陆
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T4198T.cruzi-IN-1;T.cruzi InhibitorMDK1088|||T.cruzi Inhibitor;MDK1088|||T.cruzi Inhibitor
T.cruzi-IN-1 (MDK1088) is a Trypanosoma cruzi inhibitor.
价 格:¥电议型 号:T4198产 地:中国大陆
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T41166NVS PAK1 C;NVS PAK1 CNVS PAK1 C
NVS PAK1 C is a negative control of NVS PAK1 1, a potent and selective PAK1 inhibitor.
价 格:¥电议型 号:T41166产 地:中国大陆
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T41124Kizuta saponin K11;Kizuta saponin K11Kizuta saponin K11
Kizuta saponin K11 is a saponin derived from Kalopanax pictum var. maximowiczii leaves, which is a widely used Korean medicinal plant.
价 格:¥电议型 号:T41124产 地:中国大陆
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T41085UK122UK122UK122
UK122 is a highly effective and specific inhibitor of urokinase-type plasminogen activator (uPA) with an IC50 value of 0.2 μM. It displays negligible to minimal inhibition towards tissue-type plasminogen activator (tPA), plasmin, thrombin, and trypsin (all IC50 >100 μM). Functioning as a 4-oxazolidinone analogue, UK122 is an anticancer agent that effectively inhibits cancer cell migration and invasion.
价 格:¥电议型 号:T41085产 地:中国大陆
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T40577TAK1-IN-3;TAK1 抑制剂3TAK1-IN-3;TAK1-IN-3
TAK1-IN-3 is a novel ATP-competitive TAK1 inhibitor for the study of cancer.
价 格:¥电议型 号:T40577产 地:中国大陆
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T4046BX517;化合物BX517PDK1 inhibitor 2|||BX 517|||BX-517;PDK1 inhibitor 2|||BX 517|||BX-517
BX517 (PDK1 inhibitor 2) is a potent and selective inhibitor of PDK1.
价 格:¥电议型 号:T4046产 地:中国大陆
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T40396FgGpmk1-IN-1FgGpmk1-IN-1FgGpmk1-IN-1
FgGpmk1-IN-1 is a new inhibitor of the fusarium graminearum mitogen-activated protein kinase (FgGpmk1), displaying a potency with an EC50 value of 3.46 μg/mL.
价 格:¥电议型 号:T40396产 地:中国大陆
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T40350HPK1-IN-4;化合物HPK1-IN-4HPK1-IN-4;HPK1-IN-4
HPK1-IN-4 is an HPK1 (MAPK41) inhibitor with an IC 50 of 0.061 nM. HPK1-IN-4 is often used as a preclinical immunotherapy tool compound.
价 格:¥电议型 号:T40350产 地:中国大陆
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T40348TTBK1-IN-1;TTBK1-IN-1TTBK1-IN-1;TTBK1-IN-1
TTBK1-IN-1 is a highly potent and selective inhibitor of tau tubulin kinase 1 (TTBK1), capable of penetrating the blood-brain barrier with ease. With an IC 50 value of 2.7 nM, TTBK1-IN-1 exhibits strong inhibitory activity against TTBK1. This compound holds great promise for advancing research in Alzheimer´s disease and other tauopathies.
价 格:¥电议型 号:T40348产 地:中国大陆
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T40290CDK12-IN-5;CDK12-IN-5CDK12-IN-5;CDK12-IN-5
CDK12-IN-5 is a pyrazolotriazine compound that effectively inhibits CDK12, with an IC50 value of 23.9 nM at a high ATP concentration of 2 mM. However, CDK12-IN-5 does not exhibit inhibitory effects on CDK2/Cyclin E (IC50 = 173 μM) and CDK9/Cyclin T1 (IC50 = 127 μM) at the same high ATP concentration of 2 mM, as stated in WO2021116178A1.
价 格:¥电议型 号:T40290产 地:中国大陆
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T40289CDK12-IN-6CDK12-IN-6CDK12-IN-6
CDK12-IN-6, a pyrazolotriazine compound, is a powerful inhibitor of CDK12. Its inhibitory activity is significant with an IC50 value of 1.19 μM when tested at high ATP concentration (2 mM). Notably, CDK12-IN-6 does not exhibit any inhibitory effect on CDK2/Cyclin E (IC50 >20 μM) and CDK9/Cyclin T1 (IC50 >20 μM) when tested under the same high ATP conditions (2 mM) (WO2021116178A1).
价 格:¥电议型 号:T40289产 地:中国大陆
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T40288CDK12-IN-4CDK12-IN-4CDK12-IN-4
CDK12-IN-4, a pyrazolotriazine compound, exhibits potent inhibition of CDK12 by achieving an IC50 value of 0.641 μM, utilizing high ATP levels (2 mM). Notably, CDK12-IN-4 does not impact CDK2/Cyclin E (IC50 > 20 μM) or CDK9/Cyclin T1 (IC50 > 20 μM) under the influence of high ATP (2 mM) levels (WO2021116178A1).
价 格:¥电议型 号:T40288产 地:中国大陆
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T40265PLK1-IN-2PLK1-IN-2PLK1-IN-2
PLK1-IN-2 is a PLK1 kinase inhibitor with an IC 50 value of 0.384 μM.
价 格:¥电议型 号:T40265产 地:中国大陆
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T40188HPK1-IN-20HPK1-IN-20HPK1-IN-20
HPK1-IN-19 is a potent inhibitor of hematopoietic progenitor kinase 1 (HPK1).
价 格:¥电议型 号:T40188产 地:中国大陆
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T40091Chk1-IN-6Chk1-IN-6Chk1-IN-6
Chk1-IN-6 is a potent, selective, and orally bioavailable CHK1 inhibitor candidate.
价 格:¥电议型 号:T40091产 地:中国大陆