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T5524Aurora Kinase Inhibitor IIIAurora Kinase Inhibitor III
Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR.
价 格：￥电议型 号：T5524产 地：美洲
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T58823-Bromopyruvic acid3-Bromopyruvic acid,Bromopyruvic acid,Hexokinase II Inhibitor II, 3-BP
3-Bromopyruvic acid is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition. It is inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs.
价 格：￥电议型 号：T5882产 地：美洲
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T6148CX-6258 HClCX-6258 HCl,Pim-Kinase Inhibitor X,
CX-6258 HCl is an effective, orally efficacious Pim1/2/3 kinase inhibitor (IC50: 5/25/16 nM).
价 格：￥电议型 号：T6148产 地：美洲
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T6154SU11274SU11274,PKI-SU11274,Met Kinase Inhibitor
SU11274(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.
价 格：￥电议型 号：T6154产 地：美洲
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T6250H 89 2HClH 89 2HCl,H-89 dihydrochloride,Protein kinase inhibitor H-89 dihydrochloride
H 89 is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).
价 格：￥电议型 号：T6250产 地：美洲
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T6335Tie2 kinase inhibitorTie2 kinase inhibitor
Tie2 kinase inhibitor， an optimized compound of SB-203580, is selective to Tie2 with IC50 of 0.25 μM, which is 200-fold more effective than p38.
价 格：￥电议型 号：T6335产 地：美洲
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T8817TIE-2/VEGFR-2 kinase-IN-1；化合物 T8817TIE-2/VEGFR-2 kinase-IN-1
TIE-2/VEGFR-2 kinase-IN-1 is used for the synthesis of TIE-2 and/or VEGFR-2 inhibitors that can be used for the study of diseases associated with inappropriate angiogenesis [1].
价 格：￥电议型 号：T8817产 地：中国大陆
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T8795met-kinase-in-2；化合物 T87951,6-Naphthyridin-4(1H)-one, 5-[[3-fluoro-4-[[7-(2-hydroxy-2-methylpropoxy)-
MET kinase-IN-2, a selective and potent MET kinase inhibitor, demonstrates oral bioavailability and exhibits an IC50 value of 7.4 nM. It also possesses antitumor activity[1].
价 格：￥电议型 号：T8795产 地：中国大陆
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T8467RET V804M-IN-1；化合物RET V804M-IN-1RETV804M kinase inhibitor|||LUN09945；RETV804M kinase inhibitor|||LUN
RET V804M-IN-1 (RETV804M kinase inhibitor) is a wt-RET -selective RETV804M kinase inhibitors(IC50 = 20 nM).
价 格：￥电议型 号：T8467产 地：中国大陆
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T83754PKCδ Substrate TFA；化合物 PKCδ Substrate TFAProtein Kinase Cδ Substrate；Protein Kinase Cδ Substrate
PKCδ substrate, a peptide substrate for PKCδ, facilitates the monitoring of PKCδ activity in both cell-free and cell-based assays.
价 格：￥电议型 号：T83754产 地：中国大陆
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T83728Tat-AKAP79 (326-336) TFA；化合物 Tat-AKAP79 (326-336) TFATat-A-kinase Anchor Protein 79 (326-336)；Tat-A-
Tat-AKAP79 (326-336) is a peptide that links the HIV-1 Tat protein transduction domain with an 11-amino acid sequence from A-kinase anchor protein 79 (AKAP79). This compound effectively inhibits the activation-induced sensitization by protein kinase A (PKA) or PKC of the transient receptor potential vanilloid 1 (TRPV1) at a concentration of 200 ?M in isolated rat dorsal root ganglion (DRG) neurons. Additionally, it mitigates nocifensive behavior in mice elicited by formalin or phorbol 12-myrista
价 格：￥电议型 号：T83728产 地：中国大陆
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T83670F1 TFA；化合物 F1 TFATat-IKIP (46-60)|||Tat-Inhibitor of NF-κB Kinase-interacting Peptide；Tat-IKIP (46-6
F1, an anti-inflammatory peptide, incorporates the HIV-1 Tat protein transduction domain linked with a 15-amino acid sequence from residues 46-60 of the inhibitor of NF-κB kinase-interacting peptide (IKIP). It effectively blocks LPS-induced phosphorylation of IκB kinase α (IKKα) and IKKβ, along with the nuclear translocation of NF-κB (p65) in mouse peritoneal macrophages at 5 ?M concentration. F1, administered at 5 mg/kg in vivo, significantly reduces IL-6, TNF-α, and IL-1β serum levels and enha
价 格：￥电议型 号：T83670产 地：中国大陆
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T83627Pim-1 kinase inhibitor 8；Pim-1 kinase 抑制剂 8Pim-1 kinase inhibitor 8
Pim-1 kinase inhibitor 8 is a potent Pim-1 kinase inhibitor with anticancer activity and can effectively inhibit cell migration.Pim-1 kinase inhibitor 8 is cytotoxic to MCF-7 and HepG2 cells, and is a candidate compound for breast cancer research.
价 格：￥电议型 号：T83627产 地：中国大陆
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T82174hRIO2 kinase ligand-1；hRIO2 激酶配体1hRIO2 kinase ligand-1
hRIO2 kinase ligand-1 is a potent ligand for hRIO2 kinase (Kd: 520 nM).
价 格：￥电议型 号：T82174产 地：中国大陆
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T81783MK2-IN-5；化合物 MK2-IN-5Hsp25 kinase inhibitor|||Mk2 pseudosubstrate；Hsp25 kinase inhibitor|||Mk2 pseud
MK2-IN-5, a pseudosubstrate of Mk2 with an inhibition constant (K_i) of 8 μM, selectively targets the protein interaction domain of the MAPK pathway and inhibits the phosphorylation of HSP25 and HSP27 [1] [2] [3].
价 格：￥电议型 号：T81783产 地：中国大陆
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T81740Multi-kinase-IN-6；化合物 Multi-kinase-IN-6Multi-kinase-IN-6
Multi-kinase-IN-6 (compound 10e) is a multikinase inhibitor that effectively impedes the activity of TrkA, ALK2, c-KIT, EGFR, PIM1, CK2α, CHK1, and CDK2. It exhibits antiproliferative effects on MCF7, HCT116, and EKVX cancer cell lines with IC50s of 3.36 μM, 1.40 μM, and 3.49 μM, respectively. Furthermore, Multi-kinase-IN-6 induces cell cycle arrest at the G1/S and G1 phases in MCF7 and HCT116 cells, respectively, and triggers apoptosis effectively [1].
价 格：￥电议型 号：T81740产 地：中国大陆
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T81739Multi-target kinase inhibitor 2；化合物 Multi-target kinase inhibitor 2Multi-target kinase inhibitor 2
Compound 5K (Multi-target kinase inhibitor 2) is a multi-targeted kinase inhibitor demonstrating activity against EGFR, Her2, VEGFR2, and CDK2 with IC50 values between 40 to 204 nM. It exhibits cytotoxic effects on HepG2, HeLa, MDA-MB-231, and MCF-7 cell lines, with IC50 values of 41, 57, 51, and 59 μM, respectively. Additionally, it induces cell cycle arrest and apoptosis specifically in HepG2 cells.
价 格：￥电议型 号：T81739产 地：中国大陆
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T81732Myosin light chain kinase fragment 11-19 amide；化合物 Myosin light chain kinase fragment 11-19 amideMLC
Myosin light chain kinase fragment 11-19 amide (MLCK(11-19) amide) serves both as a substrate-specific peptide inhibitor of MLCK and as an inhibitor of hypotonicity-induced Ca2+ entry. This compound has applications in the research of human cervical cancer [1] [2].
价 格：￥电议型 号：T81732产 地：中国大陆
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T80549Calmodulin Kinase IINtide, Myristoylated；化合物 Calmodulin Kinase IINtide, MyristoylatedMyr-CaMKIINtide
Myristoylated Calmodulin Kinase IINtide (Myr-CaMKIINtide) serves as a selective and noncompetitive inhibitor of CaMKII [1].
价 格：￥电议型 号：T80549产 地：中国大陆
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T80509PKC 20-28,myristoylated；化合物 PKC 20-28,myristoylatedMyristoylated protein kinase C inhibitor 20-28；My
Myristoylated protein kinase C inhibitor 20-28 (PKC 20-28,myristoylated) is a cell-permeable inhibitor of protein kinase C, utilized in cancer research [1].
价 格：￥电议型 号：T80509产 地：中国大陆
