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T7885Afuresertib hydrochloride化合物Afuresertib hydrochlorideAfuresertib|||PKC|||Protein kinase C
Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)
价 格：￥电议型 号：T7885产 地：中国大陆
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T78792Multi-kinase-IN-4；化合物 Multi-kinase-IN-4Multi-kinase-IN-4
Multi-kinase-IN-4 (compound 5d) is a multi-targeted kinase inhibitor active against VEGFR2, EGFR, HER2, and CDK2, with respective IC50 values of 0.33, 0.22, 0.18, and 2.09 μM. It exhibits broad-spectrum anti-cancer properties in HepG2, MCF-7, MDA-231, and HeLa cell lines, with IC50 values ranging from 1.94 to 7.1 ?M, and demonstrates lower toxicity in WI-38 cells (IC50 = 40.85 ?M). Additionally, it induces apoptosis and causes S-phase cell cycle arrest in HepG2 cells, and holds potential for can
价 格：￥电议型 号：T78792产 地：中国大陆
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T78753Aurora Kinases-IN-4；化合物 Aurora Kinases-IN-4Aurora Kinases-IN-4
Aurora Kinases-IN-4 (Compound 11c) is a covalent, ATP-competitive inhibitor of aurora kinase A with an IC50 value of 1.7 nM. It demonstrates cell proliferation inhibition in SJSA-1, MDA-MB-231, A549, and HeLa cell lines with IC50 values of 4.27, 1.54, 3.08, and 6.99 μM, respectively. This compound is applicable in research concerning triple-negative breast cancer (TNBC) [1].
价 格：￥电议型 号：T78753产 地：中国大陆
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T77746Tyrosine kinase-IN-7；Tyrosine kinase抑制剂7Tyrosine kinase-IN-7
Tyrosine kinase-IN-7 is a potent inhibitor of the tyrosine kinase EGFR, inhibiting EGFR(WT) and EGFR(T790M) and showing anti-cancer and anti-tumor activity in a variety of cancer cell lines. Tyrosine kinase-IN-7 has potential anti-inflammatory and antiviral activities.
价 格：￥电议型 号：T77746产 地：中国大陆
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T77709Casein kinase 1δ-IN-8；Casein kinase 1δ抑制剂8Casein kinase 1δ-IN-8
Casein kinase 1δ-IN-8 is an inhibitor of casein kinase 1δ and is used to treat neurodegenerative diseases such as Alzheimer´s disease type.
价 格：￥电议型 号：T77709产 地：中国大陆
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T77708Casein kinase 1δ-IN-7；Casein kinase 1δ抑制剂7Casein kinase 1δ-IN-7
Casein kinase 1δ-IN-7 is a Casein kinase 1δ inhibitor for neurodegenerative diseases such as Alzheimer´s disease.
价 格：￥电议型 号：T77708产 地：中国大陆
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T77648Casein kinase 1δ-IN-14；酪蛋白激酶抑制剂14WAY-637081；WAY-637081
Casein kinase 1δ-IN-14 (WAY-637081) can be used to study atherosclerosis-related cardiovascular disease.
价 格：￥电议型 号：T77648产 地：中国大陆
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T77646Multi-kinase-IN-5；化合物 Multi-kinase-IN-5Multi-kinase-IN-5
Multi-kinase-IN-5 (compound 15c) is a multi-kinase inhibitory agent that shows significant inhibition against a range of protein kinases including RET, KIT, cMet, VEGFR1, VEGFR2, FGFR1, PDGFR, and BRAF, with corresponding inhibition percentages of 74%, 31%, 62%, 40%, 73%, 74%, 59%, and 69%. Its IC50 values are 1.287 μM for FGFR1, 0.117 μM for VEGFR, and 1.185 μM for RET kinases, indicating its potency [1].
价 格：￥电议型 号：T77646产 地：中国大陆
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T77526Pim-1 kinase inhibitor 4；Pim-1 激酶 抑制剂4Pim-1 kinase inhibitor 4
Pim-1 kinase inhibitor 4 is a potent Pim-1 kinase inhibitor with an IC50 value of 17.01 nM.Pim-1 kinase inhibitor 4 also possesses antioxidant activity and potential anticancer activity, and inhibits DPPH.Pim-1 kinase inhibitor 4 promotes apoptosis and inhibits the growth of PC-3 cells with an IC50 value of 16 nM. Pim-1 kinase inhibitor 4 promotes apoptosis and inhibits PC-3 cell growth with an IC50 of 16 nM. Pim-1 kinase inhibitor 4 can be used in prostate cancer research.
价 格：￥电议型 号：T77526产 地：中国大陆
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T77501TAO Kinase inhibitor 2；TAO激酶抑制剂2TAO Kinase inhibitor 2
TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.
价 格：￥电议型 号：T77501产 地：中国大陆
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T77500Casein kinase 1δ-IN-6；化合物Casein kinase 1δ-IN-6Casein kinase 1δ-IN-6
Casein kinase 1δ-IN-6 is a potent and selective inhibitor of the protein kinase CK-1δ with an IC50 of 23 nM.Casein kinase 1δ-IN-6 shows neuroprotective and anti-inflammatory activity in both in vitro and in vivo assays.Casein kinase 1δ-IN-6 can be used to study neurodegenerative diseases.
价 格：￥电议型 号：T77500产 地：中国大陆
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T76488Calmodulin Dependent Protein Kinase Substrate；化合物 Calmodulin Dependent Protein Kinase SubstrateCalmo
Calmodulin Dependent Protein Kinase Substrate is a synthetic peptide that serves as a substrate for protein kinases and requires calcium ions (Ca 2+) and calmodulin (CaM) for activation. It specifically interacts with calmodulin-dependent protein kinases (CaMK). This compound is utilized in studies involving protein kinase activity [1].
价 格：￥电议型 号：T76488产 地：中国大陆
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T76487Calmodulin Dependent Protein Kinase Substrate Analog；化合物 Calmodulin Dependent Protein Kinase Substra
Calmodulin-Dependent Protein Kinase Substrate Analog, a synthetic peptide substrate, is activated by Ca2+ and calmodulin (CaM). It serves as a substrate for protein kinases, leveraging a dependency on Ca2+ and CaM for its function [1].
价 格：￥电议型 号：T76487产 地：中国大陆
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T76475Casein Kinase II Substrate；化合物 Casein Kinase II SubstrateCasein Kinase II Substrate
Casein Kinase II Substrate, a peptide substrate, is selectively phosphorylated by casein kinase II (CK2) [1].
价 格：￥电议型 号：T76475产 地：中国大陆
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T76458P34cdc2 Kinase Fragment；化合物 P34cdc2 Kinase FragmentP34cdc2 Kinase Fragment
P34cdc2 Kinase Fragment plays a crucial role in yeast mitosis by ensuring the completion of DNA replication and regulates microtubule polymerization in Xenopus oocytes meiosis by phosphorylating mitogen-activated protein 2 (MAP2) [1] [2].
价 格：￥电议型 号：T76458产 地：中国大陆
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T76456Protein Kinase C (19-35) Peptide；化合物 Protein Kinase C (19-35) PeptideProtein Kinase C (19-35) Peptid
Protein Kinase C (19-35) Peptide, serving as the PKC pseudosubstrate inhibitor/region, potentially inhibits PKC activity by obstructing the substrate-binding site within its kinase domain, rendering the cytoplasmic form of PKC inactive [1] [2].
价 格：￥电议型 号：T76456产 地：中国大陆
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T76444Protein Kinase C (660-673)；化合物 Protein Kinase C (660-673)Protein Kinase C (660-673)
Protein Kinase C βII V5 peptide (660-673) (PKC βII (660-673)) exhibits an affinity for binding to RACK1 [1].
价 格：￥电议型 号：T76444产 地：中国大陆
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T76422Protein Kinase C (661-671)；化合物 Protein Kinase C (661-671)Protein Kinase C (661-671)
Protein Kinase C (661-671), a fragment peptide of the β1 subspecies of Protein Kinase C (PKC), is instrumental in regulating cellular growth and has been implicated in tumor promotion [1] [2].
价 格：￥电议型 号：T76422产 地：中国大陆
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T76421Protein Kinase C β Peptide；化合物 Protein Kinase C β PeptideProtein Kinase C β Peptide
Protein Kinase C (beta) Peptide, a fragment of Protein Kinase Cβ, is associated with hyperglycemia-induced decreases in endothelium-derived nitric oxide. Inhibiting Protein Kinase Cβ forestalls the impairment of endothelium-dependent vasodilation caused by acute hyperglycemia [1].
价 格：￥电议型 号：T76421产 地：中国大陆
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T76419Protein Kinase C γ Peptide；化合物 Protein Kinase C γ PeptideProtein Kinase C γ Peptide
Protein Kinase C (gamma) Peptide, a fragment of Protein Kinase Cγ, plays a role in dominant ataxia by inhibiting the nuclear import of aprataxin, which is associated with recessive ataxia [1].
价 格：￥电议型 号：T76419产 地：中国大陆
