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T52521,11-Undecanedicarboxylic acid1,11-Undecanedicarboxylic acid,1,13-Tridecanedioic acid,Brassilic acid
Undecanedicarboxylic acid is an unusual odd-numbered dicarboxylic acid that appears in the urines of children with neonatal adrenoleukodystrophy and Zellweger syndrome, as an additional marker of these peroxisomal disorders.
价 格:¥电议型 号:T5252产 地:美洲
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T5514EpibrassinolideEpibrassinolide,24-Epibrassinolide ,B1105
Epibrassinolide (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator with a similar structure to mammalian steroids.
价 格:¥电议型 号:T5514产 地:美洲
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T5523Imidazole ketone erastinImidazole ketone erastin,IKE,
Imidazole ketone erastin (IKE) is an inducer of ferroptosis. It has inhibition of the system Xc- cystine/glutamate transporter.
价 格:¥电议型 号:T5523产 地:美洲
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T5S0802PalmatinePalmatine,Berbericinine,Burasaine
1. Palmatine is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery, hypertension, inflammation, and liver-related
价 格:¥电议型 号:T5S0802产 地:美洲
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T5S0836Astrasieversianin VIIAstrasieversianin VII,Isoastragaloside II,
Isoastragaloside II is a derivative Astragaloside I, an ingredient in Astragalus membranaceus which is reported to have osteogenic properties.
价 格:¥电议型 号:T5S0836产 地:美洲
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T5S2139Epimedin A1Epimedin A1,Hexandraside F,
Epimedin A1(Hexandraside F) is a flavonoid extracted from Herba Epimedii which is one of commonly used Chinese medicines.
价 格:¥电议型 号:T5S2139产 地:美洲
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T6278SotrastaurinSotrastaurin,AEB071,
Sotrastaurin is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).
价 格:¥电议型 号:T6278产 地:美洲
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T6300DegrasynDegrasyn,WP1130,
Degrasyn (WP1130), a specific deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor, also inhibits Bcr/Abl, which is a JAK2 transducer (without affecting 20S proteasome) and activator of transcription (STAT).
价 格:¥电议型 号:T6300产 地:美洲
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T6302LonafarnibLonafarnib,Sch66336,Sarasar
Lonafarnib is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).
价 格:¥电议型 号:T6302产 地:美洲
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T8756KRAS inhibitor-9;化合物KRAS inhibitor-9DUN09716;DUN09716
KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS inhibitor-9 selectively inhibits the proliferation of NSC-LC cells with KRAS mutation but not normal lung cells
价 格:¥电议型 号:T8756产 地:中国大陆
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T8684Sotorasib;化合物AMG-510AMG-510;AMG-510
Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C. Sotorasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Sotorasib exhibits inhibitory activity against KRAS G12C mutant tumors.
价 格:¥电议型 号:T8684产 地:中国大陆
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T8659K-Ras-PDEδ-IN-1;化合物K-Ras-PDEδ-IN-1K-Ras-PDEδ-IN-1
K-Ras-PDEδ-IN-1 is a potent inhibitor of competitive K-Ras-PDEδ.It binds to the farnesyl binding pocket of PDEδ(Kd of 8 nM).
价 格:¥电议型 号:T8659产 地:中国大陆
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T846528-high brassinolide;化合物 T846528-high brassinolide
28-high brassinolide is a natural product for research related to life sciences. The catalog number is T8465 and the CAS number is 82373-95-3.
价 格:¥电议型 号:T8465产 地:中国大陆
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T83885DXR Inhibitor 11a sodium;化合物 DXR Inhibitor 11a sodium1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase
DXR inhibitor 11a, with an IC50 value of 0.11 ?M, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also demonstrates significant activity against P. falciparum´s growth in isolated human erythrocytes, with an IC50 of 0.37 ?M.
价 格:¥电议型 号:T83885产 地:中国大陆
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T8369Adagrasib;化合物MRTX849MRTX849;MRTX849
Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib exhibits inhibitory activity against KRAS G12C mutant tumors.
价 格:¥电议型 号:T8369产 地:中国大陆
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T83679Parasin I (catfish) TFA;化合物 Parasin I (catfish) TFAParasin I (catfish) TFA
Parasin I, a peptide fragment derived from the N-terminal region of histone H2A in catfish (P. asotus), plays a critical role in host defense. This antimicrobial peptide is produced through the action of cathepsin D on histone H2A within the skin mucosa of injured P. asotus. Demonstrating efficacy against a spectrum of Gram-positive and Gram-negative bacteria, as well as fungi, Parasin I exhibits minimum inhibitory concentrations (MICs) of 1-2 ?g/ml, 1-4 ?g/ml, and 1-2 ?g/ml, respectively.
价 格:¥电议型 号:T83679产 地:中国大陆
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T83137ALP/Carbonic anhydrase-IN-1;化合物 ALP/Carbonic anhydrase-IN-1ALP/Carbonic anhydrase-IN-1
Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkaline phosphatase (ALP). It exhibits inhibitory IC50 values of 0.44 ?M for CA-II, 1.61 ?M for CA-IX, 0.51 ?M for CA-XII, and 0.107 ?M for ALP [1].
价 格:¥电议型 号:T83137产 地:中国大陆
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T83134Alterbrassicene B;化合物 Alterbrassicene BAlterbrassicene B
Alterbrassicene B, an anticancer agent, is isolatable from the fungus Alternaria brassicicola [1].
价 格:¥电议型 号:T83134产 地:中国大陆
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T83025Antiparasitic agent-19;化合物 Antiparasitic agent-19Antiparasitic agent-19
Antiparasitic Agent-19 (Compound 40) is a broad-spectrum antiparasitic with minimal toxicity to Trypanosoma brucei, Leishmania infantum, and Trypanosoma cruzi [1].
价 格:¥电议型 号:T83025产 地:中国大陆