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T79147KRAS degrader-1;化合物 KRAS degrader-1KRAS degrader-1
KRAS degrader-1 (compound 1) is a potent agent that selectively targets KRAS proteins for destruction via the autophagy-lysosomal degradation pathway [1].
价 格:¥电议型 号:T79147产 地:中国大陆
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T79072KRAS G12D modulator-1;化合物 KRAS G12D modulator-1KRAS G12D modulator-1
KRAS G12D modulator-1 (compound 6), a potent modulator of KRAS G12D, exhibits IC50 values ranging from 1-10 μM against NEA-G12D, PPI-G12D, and p ERK-AGS, and is utilized in cancer research [1].
价 格:¥电议型 号:T79072产 地:中国大陆
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T79057KRAS G12C inhibitor 58;化合物 KRAS G12C inhibitor 58KRAS G12C inhibitor 58
KRAS G12C inhibitor 58 is utilized in cancer research as an inhibitor of the KRAS G12C mutation [1].
价 格:¥电议型 号:T79057产 地:中国大陆
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T79026Tankyrase-IN-5;化合物 Tankyrase-IN-5Tankyrase-IN-5
Tankyrase-IN-5 (Compound 30f), structurally related to MSC2504877, effectively inhibits tankyrase isoforms TNKS1 and TNKS2, with half-maximal inhibitory concentrations (IC50s) of 2.3 nM and 7.9 nM, respectively [1].
价 格:¥电议型 号:T79026产 地:中国大陆
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T78966Antiparasitic agent-17;化合物 Antiparasitic agent-17Antiparasitic agent-17
Antiparasitic Agent-17 (compound 5u), an orally active antiparasitic, demonstrates inhibition against both Chloroquine-sensitive (Pf3D7) and Chloroquine-resistant (PfK1) strains, with IC50 values of 0.96 μM and 1.67 μM, respectively [1].
价 格:¥电议型 号:T78966产 地:中国大陆
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T78866DNA Gyrase-IN-9;化合物 DNA Gyrase-IN-9DNA Gyrase-IN-9
DNA Gyrase-IN-9 (compound 4j), an antibacterial agent, selectively targets DNA gyrase. It exhibits a minimum inhibitory concentration (MIC) of 0.5-2 ?g/mL for Gram-positive bacteria inhibition and a minimum bactericidal concentration (MBC) of 2-8 ?g/mL for Gram-positive bacteria eradication. Notably, this compound hinders DNA gyrase activity in Staphylococcus aureus with an IC50 of 6.29 ?g/mL [1].
价 格:¥电议型 号:T78866产 地:中国大陆
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T78840Carbonic anhydrase inhibitor 15;化合物 Carbonic anhydrase inhibitor 15Carbonic anhydrase inhibitor 15
Carbonic Anhydrase Inhibitor 15 (Compound 8), with an inhibitory constant (K_i) of 8.5 nM for hCA II, exhibits analgesic effects [1].
价 格:¥电议型 号:T78840产 地:中国大陆
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T78776DNA gyrase B-IN-3;化合物 DNA gyrase B-IN-3DNA gyrase B-IN-3
DNA gyrase B-IN-3 (Compound A), with an IC50 of less than 10 nM, acts as an inhibitor of bacterial DNA gyrase B and exhibits antibacterial activity against Gram-positive strains [1].
价 格:¥电议型 号:T78776产 地:中国大陆
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T78717Topoisomerase inhibitor 2;化合物 Topoisomerase inhibitor 2Topoisomerase inhibitor 2
Topoisomerase Inhibitor 2 (18C) is a broad-spectrum bacterial topoisomerase inhibitor effective against multidrug-resistant Gram-negative bacteria [1].
价 格:¥电议型 号:T78717产 地:中国大陆
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T78712DNA Gyrase-IN-8;化合物 DNA Gyrase-IN-8DNA Gyrase-IN-8
DNA Gyrase-IN-8 is a potent inhibitor of DNA gyrase, demonstrating antimicrobial activity with an IC50 of 8.45 ?M [1].
价 格:¥电议型 号:T78712产 地:中国大陆
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T78651Glecirasib;化合物 GlecirasibJAB-21822|||KRAS G12C inhibitor 36;JAB-21822|||KRAS G12C inhibitor 36
Glecirasib (KRAS G12C inhibitor 36) is a potent inhibitor targeting the oncogenic KRAS G12C mutation, a key signaling molecule within the Ras protein family that is crucial for cell growth and development. This compound shows promise for the investigation of cancers mediated by KRAS G12C mutations[1].
价 格:¥电议型 号:T78651产 地:中国大陆
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T78569CPT2;化合物 CPT2Carnitine palmitoyltransferase 2;Carnitine palmitoyltransferase 2
Carnitine palmitoyltransferase 2 (CPT2), an enzyme involved in fatty acid oxidation, serves as a prognostic biomarker for colorectal cancer (CRC). Overexpression of CPT2 activates phosphorylated p53, enhancing its expression, which in turn suppresses tumor growth and induces apoptosis. Conversely, a deficiency in CPT2 leads to the prevalent hereditary disorder of long-chain fatty acid oxidation in skeletal muscle. Additionally, the downregulation of CPT2 correlates strongly with the advancement
价 格:¥电议型 号:T78569产 地:中国大陆
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T78442TSPP tetrasodium;化合物 TSPP tetrasodiumTSPP tetrasodium
TSPP tetrasodium, a photosensitizer, has demonstrated significant efficacy in the in vivo regression of cancer and microbial infections (Ex: 413 nm, Em: 640 nm) [1][2].
价 格:¥电议型 号:T78442产 地:中国大陆
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T78364Alanine aminotransferase;化合物 Alanine aminotransferaseAlanine aminotransferase
Alanine aminotransferase (ALT), a pyridoxal-dependent enzyme, catalyzes the reversible interconversion of L-alanine and 2-oxoglutarate into pyruvate and L-glutamate [1].
价 格:¥电议型 号:T78364产 地:中国大陆
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T78353alpha-2,6-Sialyltransferase (Pd26ST);化合物 alpha-2,6-Sialyltransferase (Pd26ST)alpha-2,6-Sialyltransfe
Alpha-2,6-Sialyltransferase (Pd26ST) efficiently catalyzes the sialylation of both terminal and internal galactose and N-acetylgalactosamine residues, resulting in the production of terminal α2,6-sialosides [1].
价 格:¥电议型 号:T78353产 地:中国大陆
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T78352N-acetylglucosamine-1-P uridyltransferase (AGX1);化合物 N-acetylglucosamine-1-P uridyltransferase (AGX1
N-acetylglucosamine-1-P uridyltransferase (AGX1) (GlcNAc1pUT) is a bifunctional enzyme that couples with GlcNAc-1-P and UTP to catalyze the synthesis of UDP-GlcNAc through an uridyltransfer reaction. It exhibits acetyltransferase and uridyltransferase activities, and its presence is exclusive to prokaryotes [1].
价 格:¥电议型 号:T78352产 地:中国大陆
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T78328Efbemalenograstim alfa;化合物 Efbemalenograstim alfaF 627|||Bineuta|||Benegrastim;F 627|||Bineuta|||Ben
Efbemalenograstim alfa (F 627) is a recombinant fusion protein comprising a long-acting dimeric granulocyte colony-stimulating factor (G-CSF) with two human G-CSF molecules connected via a peptide linker to a human immunoglobulin G2 (hIgG2)-Fc fragment. This biopharmaceutical agent induces the production of white blood cells [1].
价 格:¥电议型 号:T78328产 地:中国大陆
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T78212RMC-9805;化合物 RMC-9805KRAS G12D inhibitor 18|||KRAS G12D IN 18;KRAS G12D inhibitor 18|||KRAS G12D IN
RMC-9805 is a potent KRAS G12D inhibitor with potential anti-tumor and inhibitory activity against tumor cell proliferation for the study of pancreatic cancer.
价 格:¥电议型 号:T78212产 地:中国大陆
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T78170Kras4B G12D-IN-1;Kras4B G12D 抑制剂 1Kras4B G12D-IN-1
Kras4B G12D-IN-1 is an anticancer agent that functions as an inhibitor of the Kras4B G12D protein. It effectively reduces the expression of Kras protein in mouse embryonic fibroblasts (MEFs) harboring the Kras4B G12D mutation[1].
价 格:¥电议型 号:T78170产 地:中国大陆
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T78131Emtricitabine triphosphate tetrasodium salt;化合物 Emtricitabine triphosphate tetrasodium salt(-)-Emtri
Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of the phosphorylated anabolite (-)-Emtricitabine triphosphate, an active nucleoside reverse transcriptase inhibitor that is effective against HIV and HBV [1].
价 格:¥电议型 号:T78131产 地:中国大陆