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T5381A-893;化合物 A-893A-893
A-893 is a cell-active inhibitor of Methyltransferase SMYD2 (IC 50 = 2.8 nM) .
价 格:¥电议型 号:T5381产 地:中国大陆
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T4469Nemorubicin;奈莫柔比星Methoxymorpholinyldoxorubicin|||PNU-152243A|||PNU 152243;Methoxymorpholinyldoxorubi
Nemorubicin (PNU 152243) is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile. The drug is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives.
价 格:¥电议型 号:T4469产 地:中国大陆
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T4318EOC317;化合物ACTB1003ACTB-1003|||ACTB1003|||ACTB 1003;ACTB-1003|||ACTB1003|||ACTB 1003
EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).
价 格:¥电议型 号:T4318产 地:中国大陆
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T4186AC-264613;化合物AC264613AC264613;AC264613
AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macrophages. AC-264613(AC264613) activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 30 to 100 nM.
价 格:¥电议型 号:T4186产 地:中国大陆
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T41232GSK 2833503A;GSK 2833503AGSK 2833503A
GSK 2833503A is a potent and selective TRPC6 and TRPC3 antagonist (IC50 = 3-16 nM and 21-100 nM, respectively). GSK 2833503A exhibits >63-fold selectivity over other ion channels, including other TRP channels, CaV1.2, hERG and NaV1.5. GSK 2833503A suppresses angiotensin II or endothelin-1-induced cardiac hypertrophy signaling in HEK293 cellsin vitroand in cardiomyocytes.
价 格:¥电议型 号:T41232产 地:中国大陆
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T4111Blarcamesine hydrochloride;化合物Anavex 2-73Anavex 2-73|||AVex-73 hydrochloride|||AE-37 hydrochloride;A
Blarcamesine hydrochloride (AVex-73 hydrochloride) is a Sigma-1 Receptor agonist (IC50: 860 nM).
价 格:¥电议型 号:T4111产 地:中国大陆
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T40886OnzigolideOnzigolideBIM-23A760|||TBR-760|||Onzigolide
Onzigolide (BIM-23A760), a chimeric compound combining properties of both dopamine and somatostatin, exhibits strong agonistic activity towards the D2 subtype of dopamine receptors (D2R) as well as type 2 somatostatin receptors (SSTR2).
价 格:¥电议型 号:T40886产 地:中国大陆
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T40551ACAT-IN-3;ACAT-IN-3ACAT-IN-3
ACAT-IN-3, a potent inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT), effectively suppresses NF-κB dependent transcription.
价 格:¥电议型 号:T40551产 地:中国大陆
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T40479Anticancer agent 13;Anticancer agent 13Anticancer agent 13
Anticancer agent 13 is an anticancer agent from dicarboxylic acids and amines.
价 格:¥电议型 号:T40479产 地:中国大陆
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T40398Crinecerfont hydrochloride;Crinecerfont hydrochlorideSSR-125543A|||SSR-125543 hydrochloride;SSR-1255
Crinecerfont hydrochloride (SSR-125543) is a highly potent, orally active, non-peptide antagonist of the CRF1 receptor. It has demonstrated efficacy in the context of Classic congenital adrenal hyperplasia (CAH) research.
价 格:¥电议型 号:T40398产 地:中国大陆
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T40345AV-153;AV-153AV-153
AV-153 is a 1,4-dihydropyridine derivative with antimutagenic properties. It intercalates into DNA at single strand breaks, resulting in reduced DNA damage and stimulation of DNA repair in human cells in vitro. AV-153 also interacts with thymine and cytosine and influences poly(ADP)ribosylation. Moreover, AV-153 exhibits anti-cancer activity.
价 格:¥电议型 号:T40345产 地:中国大陆
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T3A2467Allocryptopine;别隐品碱Thalictrimine|||Fagarine I;Thalictrimine|||Fagarine I|||别隐品碱
Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively.
价 格:¥电议型 号:T3A2467产 地:中国大陆
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T3A2414Manninotriose;甘露三糖Manninotriose
Manninotriose is the main carbohydrate of Ono sesame (Lamium. Lamiaceae), participates in RFO metabolism and may play an important role.
价 格:¥电议型 号:T3A2414产 地:中国大陆
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T39889Antitumor agent-23;Antitumor agent-23Antitumor agent-23
Antitumor agent-23 exhibits potent antitumoral activity, as demonstrated by its GI50 values of 38, 48, 5, 27, 80, and 28 nM against the lymphoma cell lines GRANTA-519, KARPAS-422, KARPAS-299, RAMOS, DAUDI, and RAJI respectively.
价 格:¥电议型 号:T39889产 地:中国大陆
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T39886Antistaphylococcal agent 3;Antistaphylococcal agent 3Antistaphylococcal agent 3
Antistaphylococcal agent 3 is an antistaphylococcal therapeutic agent.
价 格:¥电议型 号:T39886产 地:中国大陆
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T39738ASP2453;化合物ASP2453ASP2453
ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C. ASP2453 inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM.
价 格:¥电议型 号:T39738产 地:中国大陆
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T39707AS-1763;化合物AS-1763AS-1763
AS-1763 is an orally available and selective BTK inhibitor with an IC50 of 0.85 nM.
价 格:¥电议型 号:T39707产 地:中国大陆
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T39442AM-8123;AM-8123AM-8123
AM-8123 is an APJ agonist with high oral bioavailability and potency. It effectively inhibits Forskolin-stimulated cAMP production and activates Gα proteins. This compound is valuable for cardiovascular disease research.
价 格:¥电议型 号:T39442产 地:中国大陆
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T38878Antibacterial agent 53;Antibacterial agent 53Antibacterial agent 53
Antibacterial agent 53 (example 19) is a antibacterial agent.
价 格:¥电议型 号:T38878产 地:中国大陆
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T38876Antibacterial agent 33;Antibacterial agent 33Antibacterial agent 33
Antibacterial Agent 33, a potent antibacterial compound, effectively decreases the minimum inhibitory concentration (MIC) of Ceftazidime, another antibacterial agent.
价 格:¥电议型 号:T38876产 地:中国大陆