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T62348A1AR antagonist 3；化合物 A1AR antagonist 3A1AR antagonist 3
A1AR antagonist 3 (compound 13) is a selective adenylate 1 (A1) receptor antagonist that acts on human A1 (Ki: 9.69 nM) and rat A1 (Ki: 0.529 nM). A1AR antagonist 3 can be used to study neurological diseases.
价 格：￥电议型 号：T62348产 地：中国大陆
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T62288AD013；化合物 AD013AD013
AD013 is a dual cACE and NEP inhibitor. AD013 is a C-domain selective ACE inhibitor of lenopril-tryptophan synthesis. AD013 has the potential to provide potent anti-hypertensive and cardioprotective effects.
价 格：￥电议型 号：T62288产 地：中国大陆
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T62211Antifungal agent 33；化合物 Antifungal agent 33Antifungal agent 33
Antifungal agent 33 (compound 4e) is a potent antifungal agent with significant antifungal activity against Candida albicans (MIC: 16 μg/ml). (IC50: 0.19 μg/ml).
价 格：￥电议型 号：T62211产 地：中国大陆
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T62116ALK5-IN-33；化合物 ALK5-IN-33ALK5-IN-33
ALK5-IN-33 (Compound EX-10) is an orally active, selective inhibitor of ALK-5 (IC50 ≤ 10 nM).
价 格：￥电议型 号：T62116产 地：中国大陆
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T61957Aldose reductase-IN-3；化合物 Aldose reductase-IN-3Aldose reductase-IN-3
Aldose reductase-IN-3 (Compound 5) is an effective and moderately selective aldose reductase (AR) inhibitor (IC50=3.99 μ M). Aldose reductase is a molecular target involved in various inflammatory diseases (including sepsis). Aldose reductase-IN-3 has research potential in sepsis.
价 格：￥电议型 号：T61957产 地：中国大陆
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T61823Anticancer agent 63；化合物 Anticancer agent 63Anticancer agent 63
Anticancer agent 63 (compound 3h) exhibits significant cytotoxic activity against multiple cancer cell lines, including SW480, HeLa, A549, and MCF-7, with IC 50 values of 4.9, 11.5, 9.4, and 3.4 μM, respectively, after 24 hours of treatment. In particular, Anticancer agent 63 induces apoptosis in MCF-7 cells by down-regulating Bcl-2 expression and up-regulating IL-2 and Caspase-3 expression. Additionally, Anticancer agent 63 demonstrates antioxidative properties [1].
价 格：￥电议型 号：T61823产 地：中国大陆
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T61813AMPA receptor antagonist-3；AMPA受体拮抗剂3AMPA receptor antagonist-3
AMPA receptor antagonist-3 is an AMPA receptor antagonist.
价 格：￥电议型 号：T61813产 地：中国大陆
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T61656Antitumor agent-53；化合物 Antitumor agent-53Antitumor agent-53
Antitumor agent-53 is a potent compound that effectively inhibits tumor growth. It achieves this by inducing cell cycle arrest at the G2/M phase and promoting apoptosis in HGC-27 cells through the inhibition of the PI3K/AKT pathway. Furthermore, Antitumor agent-53 holds promise for further research in the treatment of gastrointestinal tumors [1].
价 格：￥电议型 号：T61656产 地：中国大陆
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T61584ASK1-IN-3；化合物 ASK1-IN-3ASK1-IN-3
ASK1-IN-3 is a highly potent and selective inhibitor of ASK1 kinase, demonstrating an IC 50 of 33.8 nM. This compound also exhibits inhibitory effects on various cell cycle regulating kinases. ASK1-IN-3 showcases remarkable induction of apoptosis in HepG2 cancer cells and displays potent activity in arresting the cell cycle [1].
价 格：￥电议型 号：T61584产 地：中国大陆
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T61580Autophagy inducer 3；化合物 Autophagy inducer 3Autophagy inducer 3
Autophagy Inducer 3 is a chemical compound that exhibits autophagy-induced activity, specifically inducing robust autophagic cell death in various cancer cells while sparing normal cells. This compound induces lethal autophagy through the formation of distinct autophagic vacuoles, LC3 puncta formation, and upregulation of signature autophagy markers such as Beclin and Atg family proteins [1].
价 格：￥电议型 号：T61580产 地：中国大陆
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T61576Anticancer agent 83；化合物 Anticancer agent 83Anticancer agent 83
Anticancer Agent 83, a potent inhibitor of LOX IMVI cell growth, demonstrates anticancer efficacy with a GI50 value of 0.15 mM. It disrupts mitochondrial membrane potential and induces DNA damage, thereby promoting apoptosis in leukemia cells [1].
价 格：￥电议型 号：T61576产 地：中国大陆
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T61552ATG7-IN-3；化合物 ATG7-IN-3ATG7-IN-3
ATG7-IN-3 (compound 18) is an effective inhibitor of ATG7, with a potency of 0.048 μM as determined by its IC50 value. It exhibits inhibitory actions on autophagy. Moreover, ATG7-IN-3 effectively hampers the development of endogenous LC3B puncta in the H4 neuroglioma cell line [1].
价 格：￥电议型 号：T61552产 地：中国大陆
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T61471Antitubercular agent-13；化合物 Antitubercular agent-13Antitubercular agent-13
Antitubercular agent-13 (Compound 3d) is an antitubercular agent with MIC values of 0.007 μg/mL and 1.851 μg/mL against MTB H37Rv and MDR-MTB 16833, respectively. Antitubercular agent-13 shows metabolic instability [1].
价 格：￥电议型 号：T61471产 地：中国大陆
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T61391Antileishmanial agent-3；化合物 Antileishmanial agent-3Antileishmanial agent-3
Antileishmanial agent-3 (Compound 13) effectively inhibits the growth of Leishmania major [1].
价 格：￥电议型 号：T61391产 地：中国大陆
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T6139A-674563化合物A-674563A674563
A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
价 格：￥电议型 号：T6139产 地：中国大陆
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T61312Antioxidant agent-3；化合物 Antioxidant agent-3Antioxidant agent-3
Antioxidant agent-3 (Compound 14q), a potent antioxidant, exhibits strong scavenging activity against DPPH radicals and ABTS+ radicals, with IC50 values of 26.58 μM and 30.31 μM, respectively. Additionally, it enhances the levels of reactive oxygen species (ROS), superoxide dismutase (SOD), and glutathione (GSH), while diminishing lactate dehydrogenase (LDH) in H2O2-treated HepG2 cells [1].
价 格：￥电议型 号：T61312产 地：中国大陆
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T61200Antimalarial agent 3；化合物 Antimalarial agent 3Antimalarial agent 3
Antimalarial agent 3, an antimalarial agent, exhibits potent activity against Plasmodium with an IC50 of 0.035 μM. Furthermore, it demonstrates an exceptionally high selectivity index in relation to mammalian cells.
价 格：￥电议型 号：T61200产 地：中国大陆
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T61046Anticancer agent 43；抗癌剂43Anticancer agent 43
Anticancer agent 43 is a potent anticancer agent that induces apoptosis through caspase 3, PARP1, and Bax protein-dependent pathways.Anticancer agent 43 induces DNA damage and can be used in the study of glioblastoma in rats.
价 格：￥电议型 号：T61046产 地：中国大陆
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T60987Androgen receptor antagonist 3；化合物 Androgen receptor antagonist 3Androgen receptor antagonist 3
Androgen receptor antagonist 3 (Compound C18) has anticancer activities that is an antagonist of androgen receptor (AR) (IC 50 = 2.4 μM) [1].
价 格：￥电议型 号：T60987产 地：中国大陆
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T60872Adenosine receptor antagonist 3；化合物 Adenosine receptor antagonist 3Adenosine receptor antagonist 3
Adenosine receptor antagonist 3 has the potential for cancer disease research which is a potent adenosine receptor antagonist [1].
价 格：￥电议型 号：T60872产 地：中国大陆
