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  • T71423AZD5213;化合物 AZD-5213AZD5213

    AZD5213 is a selective, competitive antagonist of the human H3 receptor, exhibiting a pK i of 9.3 against hH3R. It is utilized in the research of sleep and cognitive regulation.

    价 格:¥电议型 号:T71423产 地:中国大陆

  • T71357AZD-3783;化合物 AZD-3783AZD-3783

    AZD-3783 is a selective 5-hydroxytryptamine 1B receptor antagonist with probable antidepressant and anxiolytic activity.

    价 格:¥电议型 号:T71357产 地:中国大陆

  • T71325ANA-773;化合物 ANA-773ANA-773

    ANA773 is a Toll-like Receptor 7 (TLR7) agonist prodrug with potential immunostimulating activity. Upon oral administration, ANA773 is metabolized into its active form that binds to and activates TLR7, thereby stimulating dendritic cells (DCs) and enhancing natural killer cell (NK) cytotoxicity. This activation results in the production of proinflammatory cytokines, including interferon alpha, and enhanced antibody-dependent cellular cytotoxicity (ADCC). TLR7 is a member of the TLR family, which

    价 格:¥电议型 号:T71325产 地:中国大陆

  • T71234AGN-190383;化合物 AGN-190383AGN-190383

    AGN-190383 is a phospholipase inhibitor with topical anti-inflammatory activity.

    价 格:¥电议型 号:T71234产 地:中国大陆

  • T71120AR-13503;化合物 AR-13503AR-13503

    AR-13503, is an metabolite of Netarsudil (AR-11324), is a Rho-associated protein kinase inhibitor. Netarsudil is potential useful for treating glaucoma and?/or reducing intraocular pressure.

    价 格:¥电议型 号:T71120产 地:中国大陆

  • T71105AZD2353;化合物 AZD2353AZD2353

    AZD2353 is a potent inhibitor of diacylglycerol acetyl transferase 1 (DGAT1).

    价 格:¥电议型 号:T71105产 地:中国大陆

  • T70850MDL-28133A;化合物 MDL-28133AMDL-28133A

    MDL-28133A is a 5-HT2 receptor antagonist.

    价 格:¥电议型 号:T70850产 地:中国大陆

  • T70575AS 183;化合物 AS 183AS 183

    AS 183 is an inhibitor of cholesterol acyltransferase (ACAT).

    价 格:¥电议型 号:T70575产 地:中国大陆

  • T70404MPV-2213AD;化合物 MPV-2213ADMPV-2213AD

    MPV-2213AD is an aromatase inhibitor.

    价 格:¥电议型 号:T70404产 地:中国大陆

  • T70385CGS-27023A HCl;化合物 CGS-27023A HClCGS-27023A HCl

    CGS-27023A is a novel matrix metalloproteinase inhibitor.

    价 格:¥电议型 号:T70385产 地:中国大陆

  • T70315AGI-16903;化合物 AGI-16903AGI-16903

    AGI-16903 is a metabolite of enasidenib -- an isocitrate dehydrogenase-2 inhibitor that has been shown to inhibit human nucleoside transporters and uptake of azacitidine in oocytes.

    价 格:¥电议型 号:T70315产 地:中国大陆

  • T702683A-MPLA;化合物 3A-MPLA3A-MPLA

    Monophosphoryl lipid A (MPLA) is a natural agonist for the toll-like receptor-4 (TLR4). It is useful as an adjuvant in immunization. MPLA is a safe prophylactic agent and has immunotherapeutic applications. It induces tumor necrosis factor and interleukin (IL)-1β, however not as efficient as lipopolysaccharide (LPS). MPLA improves immune response during bacterial sepsis infection.

    价 格:¥电议型 号:T70268产 地:中国大陆

  • T69996A-75943;化合物 A-75943A-75943

    A-75943 is a bone resorption inhibitor from streptomyces.

    价 格:¥电议型 号:T69996产 地:中国大陆

  • T6988SKF 38393 hydrochloride;化合物SKF38393 HCl(±)-SKF-38393 hydrochloride|||SKF-38393A|||SKF38393 HCl;(±)-S

    SKF 38393 hydrochloride (SKF38393 HCl) is a selective dopamine D1/D5 receptor agonist.

    价 格:¥电议型 号:T6988产 地:中国大陆

  • T69821AMP423;化合物 AMP423AMP423

    AMP423 is a naphthyl derivative of 2-cyanoaziridine-1-carboxamide with structural similarity to the pro-oxidant anti-tumor agent imexon. AMP423 was active in SCID mice bearing 8226/S myeloma and SU-DHL-6 B-cell lymphoma tumors, with a median tumor growth delay (T-C) of 21 days (P = 0.0002) and 5 days (P = 0.004), respectively, and a median tumor growth inhibition (T/C) of 33.3% (P = 0.03) and 82% (P = 0.01), respectively. In non-tumor-bearing mice, AMP423 was not myelosuppressive.

    价 格:¥电议型 号:T69821产 地:中国大陆

  • T69816ATZ-1993;化合物 ATZ-1993ATZ-1993

    ATZ-1993 is an Endothelin Receptor Antagonist.

    价 格:¥电议型 号:T69816产 地:中国大陆

  • T69470HC103A;化合物 HC103AHC103A

    HC103A is an inhibitor of Mycobacterium tuberculosis DosRST signaling and persistence.

    价 格:¥电议型 号:T69470产 地:中国大陆

  • T69431A-420983;化合物 A-420983A-420983

    A-420983 is a novel potent Lck inhibitor, exhibiting oral efficacy in animal models of delayed-type hypersensitivity and organ transplant rejection.

    价 格:¥电议型 号:T69431产 地:中国大陆

  • T69384AF-013;化合物 AF-013AF-013

    AF-013 is a rifamycin derivative -- specifically an O-n-octyloxime of 3-formylrifamycin SV -- which acts as an inhibitor of nucleic acid polymerases.

    价 格:¥电议型 号:T69384产 地:中国大陆

  • T69243AK963;化合物 AK963AK963

    AK963, also known as 40708899, is a potent PAK1 (p21-activated kinase 1) inhibitor, which suppresses the proliferation of human gastric cancer cells significantly by downregulation of PAK1-NFκB-CyclinB1 pathway.

    价 格:¥电议型 号:T69243产 地:中国大陆

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