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T76503Defensin NP-3A;化合物 Defensin NP-3ADefensin NP-3A
Defensin NP-3A (NP-3A; Corticostatin 1), a human granulocyte peptide, exhibits anti-ACTH activity. It belongs to the defensins, a group of antimicrobial peptides known for their antimicrobial and cytotoxic activities [1] [2].
价 格:¥电议型 号:T76503产 地:中国大陆
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T76408Autocamtide-3;化合物 Autocamtide-3Autocamtide-3
Autocamtide-3, a selective substrate for CaMKII (Ca2+/calmodulin-dependent kinase II) (CaMK), comprises a 13-amino-acid peptide featuring Thr287 [1].
价 格:¥电议型 号:T76408产 地:中国大陆
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T75966C3a (70-77) (TFA);化合物 C3a (70-77) (TFA)C3a (70-77) (TFA)
Complement 3a (70-77) TFA is an octapeptide that corresponds to the COOH terminus of C3a and exhibits the specificity and 1 to 2% biological activities of C3a [1] [2].
价 格:¥电议型 号:T75966产 地:中国大陆
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T75176Antifungal agent 53;化合物 Antifungal agent 53Antifungal agent 53
Antifungal Agent 53 (A03), a potent Candida albicans CYP51 inhibitor, exhibits antifungal activity by preventing fungi biofilm formation and demonstrates good safety [1].
价 格:¥电议型 号:T75176产 地:中国大陆
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T75172Antibacterial agent 143;化合物 Antibacterial agent 143Antibacterial agent 143
Compound 5a (Antibacterial agent 143) is an antibacterial agent exhibiting minimum inhibitory concentrations (MICs) of 25 μg/mL against B. subtilis ATCC6633 and S. aureus ATCC6538, and 50 μg/mL against P. aeruginosa ATCC13525 and E. coli ATCC35218, demonstrating its effectiveness in inhibiting bacterial growth [1].
价 格:¥电议型 号:T75172产 地:中国大陆
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T75002Antidepressant agent 3;化合物 Antidepressant agent 3Antidepressant agent 3
Antidepressant agent 3, an orally active compound, showcases multifaceted pharmacological properties including antidepressant, anxiolytic, performance-enhancing, and nootropic activities [1].
价 格:¥电议型 号:T75002产 地:中国大陆
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T74993A3AR modulator 1;化合物 A3AR modulator 1A3AR modulator 1
A3AR modulator 1 (MRS8054), an orally active positive allosteric modulator (PAM) of the A3 adenosine receptor (A3AR) (Adenosine Receptor), significantly enhances the efficacy (E max) of Cl-IB-MECA-stimulated [35 S]GTPγS binding [1].
价 格:¥电议型 号:T74993产 地:中国大陆
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T7497L1C3a 70-77 acetate;化合物C3a 70-77 acetateC3a 70-77 acetate (63555-63-5 Free base);C3a 70-77 acetate (63
C3a 70-77 acetate is the octapeptide acetate corresponding to the COOH terminus of C3a, exhibits the specificity and 1 to 2% biologic activities of C3a.
价 格:¥电议型 号:T7497L1产 地:中国大陆
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T7497LC3a 70-77 2TFA(63555-63-5(free base));化合物C3a 70-77 2TFAComplement 3a (70-77);Complement 3a (70-77)
C3a 70-77 2TFA(63555-63-5(free base)) (Complement 3a (70-77)) is an octapeptide corresponding to the COOH terminus of C3a.
价 格:¥电议型 号:T7497L产 地:中国大陆
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T74977Antibacterial agent 123;化合物 Antibacterial agent 123Antibacterial agent 123
Antibacterial Agent 123 (Compound 111) serves as an effective membrane-disrupting agent targeting antibiotic-resistant Gram-positive bacteria [1].
价 格:¥电议型 号:T74977产 地:中国大陆
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T7497C3a (70-77);化合物C3a 70-77Complement 3a (70-77)|||C3a 70-77;Complement 3a (70-77)|||C3a 70-77
C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a.
价 格:¥电议型 号:T7497产 地:中国大陆
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T74950Antitumor agent-73;化合物 Antitumor agent-73Antitumor agent-73
Antitumor Agent-73, a derivative of Diosgenin, both impedes STAT3 signaling and exogenously stimulates Pdia3/ERp57. This compound demonstrates significant antineoplastic efficacy, exhibiting potency against diverse cancer cell lines that ranges from 7.9 to 341.7 times that of Diosgenin [1].
价 格:¥电议型 号:T74950产 地:中国大陆
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T74845Antimalarial agent 23;化合物 Antimalarial agent 23Antimalarial agent 23
Antimalarial agent 23, a benzimidazole-based compound, exhibits potent antimalarial activity, demonstrated by its low IC50 values of 0.08 μM for PfNF54 and 0.10 μM for PfK1, respectively. This compound effectively inhibits β-hematin formation, yet it does not directly interfere with the conversion of heme to hemozoin [1].
价 格:¥电议型 号:T74845产 地:中国大陆
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T74844Antiproliferative agent-23;化合物 Antiproliferative agent-23Antiproliferative agent-23
Antiproliferative agent-23, a microtubule-destabilizing agent (MDA), disrupts the tubulin-microtubule system, leading to apoptosis through a mitochondrion-dependent pathway. This involves downregulation of Bcl-2 protein, upregulation of Bax and Cyt c proteins, and activation of the caspase cascade. Additionally, it induces reactive oxygen species (ROS)-mediated endoplasmic reticulum stress in A549/CDDP cells (cisplatin-resistant cancer cell line) through the PERK/ATF4/CHOP signaling pathway, dem
价 格:¥电议型 号:T74844产 地:中国大陆
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T74828AcrB-IN-3;化合物 AcrB-IN-3AcrB-IN-3
Efflux pump-IN-3, an AcrB efflux pump inhibitor, potentiates the effect of antibiotics by inhibiting the efflux of Nile Red (a known substrate of AcrB). It does not disrupt the bacterial outer membrane or exhibit toxicity in a nematode model [1].
价 格:¥电议型 号:T74828产 地:中国大陆
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T74752AA-T3A-C12;AA-T3A-C12AA-T3A-C12
AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid). AA-T3A-C12 mediates great RNA delivery and transfection of activated fibroblasts [1] .
价 格:¥电议型 号:T74752产 地:中国大陆
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T74627Angiogenesis inhibitor 3;化合物 Angiogenesis inhibitor 3Angiogenesis inhibitor 3
Angiogenesis Inhibitor 3 (Compound 8) is a potent substance that effectively inhibits the growth of HUVEC and HCT-15 cells, demonstrating IC50 values of 1.00 and 0.71 μM, respectively. It not only induces apoptosis in these cells but also exhibits significant anticancer activity by suppressing cancer cell invasion. Furthermore, this compound successfully inhibits angiogenesis in zebrafish embryos [1].
价 格:¥电议型 号:T74627产 地:中国大陆
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T74601Antitumor photosensitizer-3;化合物 Antitumor photosensitizer-3Antitumor photosensitizer-3
Antitumor Photosensitizer-3 (Compound I), a chlorin derivative, effectively induces apoptosis and necrosis in tumor cells upon exposure to 650 nm laser irradiation. This compound demonstrates reduced skin phototoxicity compared to the positive reference m-THPC in vivo [1].
价 格:¥电议型 号:T74601产 地:中国大陆
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T74494Antitumor agent-63;化合物 Antitumor agent-63Antitumor agent-63
Antitumor Agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, serves as a non-toxic antitumor agent showing high stability and very weak direct inhibition of topoisomerase I (Topo I) [1], demonstrating selective action without harming normal cells.
价 格:¥电议型 号:T74494产 地:中国大陆
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T74490Apoptosis inducer 3;化合物 Apoptosis inducer 3Apoptosis inducer 3
Apoptosis Inducer 3 (Compound 3), a selective apoptosis triggering agent, induces both apoptosis and late-apoptosis phases, demonstrating cytotoxic effects against cancer cells [1].
价 格:¥电议型 号:T74490产 地:中国大陆