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  • T80597Dafsolimab；化合物 DafsolimabSPV-T3a；SPV-T3a

    Dafsolimab (SPV-T3a), an IgG2a murine monoclonal antibody (anti-CD3), induces cell death by modulating and activating the CD3/T cell receptor complex and is utilized in research pertaining to graft-versus-host disease (GVHD) [1].

    价 格：￥电议型 号：T80597产 地：中国大陆

  • T80429π-TRTX-Hm3a；化合物 π-TRTX-Hm3aπ-TRTX-Hm3a

    π-TRTX-Hm3a, a 37-amino acid peptide derived from the venom of the Togo starburst tarantula (Heteroscodra maculata), selectively inhibits the acid-sensing ion channel 1a (ASIC1a) in a pH-dependent manner, with an inhibitory concentration half-max (IC50) of 1-2 nM, and also potentiates the activity of acid-sensing ion channel 1b (ASIC1b) with an effective concentration half-max (EC50) of 46.5 nM [1].

    价 格：￥电议型 号：T80429产 地：中国大陆

  • T80303Aurein 3.3；化合物 Aurein 3.3Aurein 3.3

    Aurein 3.3 is an antimicrobial peptide with antibiotic properties and exhibits anticancer activity [1].

    价 格：￥电议型 号：T80303产 地：中国大陆

  • T80297Aurein 2.3；化合物 Aurein 2.3Aurein 2.3

    Aurein 2.3, an antibiotic antimicrobial peptide, partially inhibits E. coli ATPase activity and suppresses cell growth [1] [2].

    价 格：￥电议型 号：T80297产 地：中国大陆

  • T80247Caloxin 3A1；化合物 Caloxin 3A1Caloxin 3A1

    Caloxin 3A1, a biologically active peptide, is a member of the caloxins, which are inhibitors of the extracellular plasma membrane (PM) Ca2+ pumps. Specifically, it inhibits plasma membrane calcium pumps (PMCAs) without affecting the sarcoplasmic reticulum Ca2+ pump, nor does it inhibit the formation of the acylphosphate intermediate from ATP.

    价 格：￥电议型 号：T80247产 地：中国大陆

  • T80246TAT-GluR23A Fusion Peptide；化合物 TAT-GluR23A Fusion PeptideTAT-GluR23A Fusion Peptide

    TAT-GluR23A Fusion Peptide is a bioactive peptide comprising the GluR23A sequence—residues 869 to 877 of GluR23Y with alanine replacing tyrosine—and an 11 amino acid cell-permeable HIV Trans-Activator of Transcription (TAT) protein transduction domain (PTD). It serves as an inactive control counterpart to the glutamate receptor endocytosis inhibitor GluR23Y, devoid of crucial phosphorylation sites.

    价 格：￥电议型 号：T80246产 地：中国大陆

  • T79891Androgen receptor degrader-3；化合物 Androgen receptor degrader-3Androgen receptor degrader-3

    Androgen Receptor Degrader-3 (ARD-3) is a compound that inhibits androgen receptor signaling and promotes the degradation of the receptor, with potential applications in prostate cancer research [1].

    价 格：￥电议型 号：T79891产 地：中国大陆

  • T79844Anticancer agent 143；化合物 Anticancer agent 143Anticancer agent 143

    Anticancer Agent 143 (Compound 369), a potent dual inhibitor targeting PTPN2 and PTP1B, exhibits IC50 values below 2.5 nM. It is employed in cancer research [1].

    价 格：￥电议型 号：T79844产 地：中国大陆

  • T79790ALPK1-IN-3；化合物 ALPK1-IN-3ALPK1-IN-3

    ALPK1-IN-3,serves as an ALPK1 inhibitor that dampens proinflammatory gene expression in the kidney and enhances survival in animal models of sepsis-induced acute kidney injury [1].

    价 格：￥电议型 号：T79790产 地：中国大陆

  • T79675Antibacterial agent 153；化合物 Antibacterial agent 153Antibacterial agent 153

    Antibacterial agent 153 is a broad-spectrum agent that eradicates bacteria by targeting their cell membranes and is employed in research on bacterial infections [1].

    价 格：￥电议型 号：T79675产 地：中国大陆

  • T79646Anticancer agent 153；化合物 Anticancer agent 153Anticancer agent 153

    Anticancer Agent 153 (Compound 3) promotes apoptosis through the generation of Reactive Oxygen Species (ROS) and elevates the loss of Mitochondrial Membrane Potential (MMP), effectively inhibiting cancer cell proliferation [1].

    价 格：￥电议型 号：T79646产 地：中国大陆

  • T79599Anti-inflammatory agent 53；化合物 Anti-inflammatory agent 53Anti-inflammatory agent 53

    Anti-inflammatory agent 52 (compound 7c) is an orally active, selective COX-2 inhibitor with demonstrated anti-HT29 metastatic activity, causing periodic arrest in the S phase and G2/M phase. This agent exhibits moderate anti-inflammatory efficacy alongside a notable safety profile. Additionally, it possesses the uncommon capability of inhibiting tumor development in a mouse model, indicative of anti-cancer properties [1].

    价 格：￥电议型 号：T79599产 地：中国大陆

  • T79548AChE/BChE-IN-13；化合物 AChE/BChE-IN-13AChE/BChE-IN-13

    AChE/BChE-IN-13 (compound 5j) serves as a potent dual inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting half-maximal inhibitory concentrations (IC50) of 20.89 μM for AChE and 17.37 μM for BChE. This compound is applicable in research related to Alzheimer´s disease (AD) [1].

    价 格：￥电议型 号：T79548产 地：中国大陆

  • T79434Antitumor agent-103；化合物 Antitumor agent-103Antitumor agent-103

    Antitumor Agent-103 (compound 24l) induces apoptosis and possesses antiproliferative and anti-colony formation properties. This compound halts the cell cycle at the G0/G1 phase, augments nitric oxide (NO) production, and demonstrates anti-tumor efficacy [1].

    价 格：￥电议型 号：T79434产 地：中国大陆

  • T79413Antifungal agent 73；化合物 Antifungal agent 73Antifungal agent 73

    Antifungal agent 73 (compound A32) effectively combats azole-resistant candidiasis by disrupting the fungal cell wall and membrane. It demonstrates potent in vivo activity against pathogenic fungi, including fluconazole-resistant strains [1].

    价 格：￥电议型 号：T79413产 地：中国大陆

  • T79410anti-TNBC agent-3；化合物 anti-TNBC agent-3anti-TNBC agent-3

    Anti-TNBC agent-3 (compound 3g) is a compound that induces apoptosis and possesses anti-cancer cell proliferation properties. It effectively inhibits tumor growth and metastasis in xenograft models of triple-negative breast cancer (TNBC) [1].

    价 格：￥电议型 号：T79410产 地：中国大陆

  • T79404A09-003；化合物 A09-003A09-003

    A09-003 is a novel cell cycle protein-dependent kinase-9 CDK-9 inhibitor.A09-003 inhibits the proliferation of a variety of leukemia cell lines and inhibits the increase of leukemia sequence-1 protein in myeloid cells.A09-003 also induces apoptosis, decreases RNA polymerase II activity, and decreases Mcl-1 expression.

    价 格：￥电议型 号：T79404产 地：中国大陆

  • T79394ALK/EGFR-IN-3；化合物 ALK/EGFR-IN-3ALK/EGFR-IN-3

    ALK/EGFR-IN-3 is a dual ALK and EGFR inhibitor that demonstrates potent anti-proliferative effects on various cancer cell lines, including H1975, PC9, and Baf3-EML4-ALK, with respective IC50 values of 0.1360, 0.0332, and 0.0339 μM [1].

    价 格：￥电议型 号：T79394产 地：中国大陆

  • T79390Antileishmanial agent-23；化合物 Antileishmanial agent-23Antileishmanial agent-23

    Antileishmanial agent-23 (compound G1/9), a potent and selective trypanothione reductase (TR) inhibitor, exhibits an IC50 of 2.24 ± 0.52 μM. It effectively inhibits the growth of Leishmania, Trypanosoma cruzi, and Trypanosoma brucei [1].

    价 格：￥电议型 号：T79390产 地：中国大陆

  • T79373A3AR agonist 2；化合物 A3AR agonist 2A3AR agonist 2

    Compound 19, a selective A3 Adenosine Receptor (A3AR) agonist (K i : 22.1 nM), effectively stimulates β-arrestin2 recruitment with an EC 50 value of 4.36 nM. This compound is utilized in research pertaining to inflammatory diseases, ischemia, cancer, neuropathic pain, liver diseases, and other chronic conditions [1].

    价 格：￥电议型 号：T79373产 地：中国大陆

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