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T60846ANO1-IN-3;化合物 ANO1-IN-3ANO1-IN-3
ANO1-IN-3 (Compound 3n) can induces apoptosis that is a potent and selective inhibitor of ANO1 with an IC 50 of 1.23 μM [1].
价 格:¥电议型 号:T60846产 地:中国大陆
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T60829AAK1-IN-3;化合物 AAK1-IN-3AAK1-IN-3
AAK1-IN-3 is a quinoline analogue that can be used in the research of neuropathic pain. AAK1-IN-3 is a brain-penetrant inhibitor of adaptor protein 2-associated kinase 1 (AAK1) (IC 50 = 11 nM) [1].
价 格:¥电议型 号:T60829产 地:中国大陆
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T60778Anti-Influenza agent 3;化合物 Anti-Influenza agent 3Anti-Influenza agent 3
Anti-Influenza agent 3 (compound 11h) is a potent anti-influenza agent with low cytotoxicity for MDCK epithelial cells. Anti-Influenza agent 3 inhibits the M2 WT and S31N ion channel conductivity. Anti-Influenza agent 3 has EC50 value of 3.29 μM for A/HK/68 (H3N2, M2-WT) and EC50 value of 2.45 μM for A/WSN/33 (H1N1, M2-S31N) strain [1].
价 格:¥电议型 号:T60778产 地:中国大陆
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T60719AR antagonist 3;化合物 AR antagonist 3AR antagonist 3
When administered intratumorally, AR antagonist 3 shows effective inhibition on the growth of tumor. AR antagonist 3 is a potent and selective antagonist of androgen receptor (AR) with an IC 50 of 0.47 μM. AR antagonist 3 dose-dependently decrease the FRET signal with an IC50 of 18.05 μM [1].
价 格:¥电议型 号:T60719产 地:中国大陆
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T60529AChE/BChE-IN-3;化合物 AChE/BChE-IN-3AChE/BChE-IN-3
AChE/BChE-IN-3 (BMC-1) is an AChE and BChE dual inhibitor with IC 50 values of 6.08 μM for electric eel AChE (elAChE) and 0.383 μM for equine serum BChE (eqBChE), respectively [1].
价 格:¥电议型 号:T60529产 地:中国大陆
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T60505Antitumor agent-43;化合物 Antitumor agent-43Antitumor agent-43
Antitumor agent-43 (Compound 4B) is a potent antitumor agent that induces cell cycle arrest at G2/M phase. Antitumor agent-43 has an IC 50 of 0.5 μM for T-24 cells [1].
价 格:¥电议型 号:T60505产 地:中国大陆
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T60468Anti-infective agent 3;化合物 Anti-infective agent 3Anti-infective agent 3
Anti-infective agent 3 is an antiprotozoal and antimycobacterial agent. Anti-infective agent 3 (compound 3l) exhibits antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC 50 values of 0.47 and 0.13 μM, respectively. Anti-infective agent 3 exhibits antimycobacterial activity against Mycobacterium smegmatis with a MIC of 4 μg/mL [1].
价 格:¥电议型 号:T60468产 地:中国大陆
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T60462Antimicrobial agent-3;化合物 Antimicrobial agent-3Antimicrobial agent-3
Antimicrobial agent-3 (Compound U10) is an antimicrobial agent that is used against bacterial, fungal, and tubercular infections [1].
价 格:¥电议型 号:T60462产 地:中国大陆
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T60444hA3AR agonist 1;化合物 hA3AR agonist 1hA3AR agonist 1
hA3AR agonist 1 is a potent human A 3 adenosine receptor (hA 3 AR) agonist (Ki = 2.40 nM) .
价 格:¥电议型 号:T60444产 地:中国大陆
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T60420Anticancer agent 73;抗癌剂73Anticancer agent 73
Anticancer agent 73 is an anticancer agent which potently targets transactivation response(TAR) RNA-binding protein 2 (TRBP) and disrupts the TRBP-Dicer interaction. Anticancer agent 73 suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells.
价 格:¥电议型 号:T60420产 地:中国大陆
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T60414Antibacterial agent 73;化合物 Antibacterial agent 73Antibacterial agent 73
Antibacterial agent 73 (compound 7a) exhibits antitubercular, antibacterial, and antifungal activities. Antibacterial agent 73 exhibits promising antitubercular activity with MIC of 0.65 μg/mL against Mtb H37Rv. Antibacterial agent 73 also exhibits cytotoxicity in MCF-7 breast cancer cell lines with IC 50 of 8.20 μM [1].
价 格:¥电议型 号:T60414产 地:中国大陆
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T60372ALDH3A1-IN-1;ALDH3A1 抑制剂 1ALDH3A1-IN-1
ALDH3A1-IN-1 is a small molecule ALDH3A1 inhibitor, (IC50:1.61 μM), which can be used for the study of hyperprolinemia and dry-Larsen syndrome.
价 格:¥电议型 号:T60372产 地:中国大陆
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T60316AV123;化合物 AV123AV123
AV123 (compound 12) is a non-cytotoxic RIPK1 inhibitor with IC 50 of 12.12 μM. AV123 blocks the TNF-α-induced necroptotic with EC 50 of 1.7 μM, but not the apoptotic cell death. AV123 can be used in the study of necrotic chronic conditions such as ischemia-reperfusion injury of the brain, heart and kidney, inflammatory diseases, neurodegenerative diseases and infectious diseases [1].
价 格:¥电议型 号:T60316产 地:中国大陆
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T60275ALDH3A1-IN-2;化合物 ALDH3A1-IN-2ALDH3A1-IN-2
ALDH3A1-IN-2 (Compound 19), a potent inhibitor of aldehyde dehydrogenases (ALDHs), demonstrates high efficacy against ALDH3A1 with an IC50 of 1.29 μM. Given the overexpression of ALDHs in multiple tumor types, including prostate cancer, ALDH3A1-IN-2 holds significant potential for cancer research [1].
价 格:¥电议型 号:T60275产 地:中国大陆
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T6023Nutlin-3a;化合物Nutlin-3a(-)-Nutlin-3|||Nutlin-3a chiral|||(?)-Nutlin-3;(-)-Nutlin-3|||Nutlin-3a chiral
Nutlin-3a ((?)-Nutlin-3), the active enantiomer of Nutlin-3, inhibits MDM2-p53 interactions and stabilizes the p53 protein.
价 格:¥电议型 号:T6023产 地:中国大陆
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T602241H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-;化合物T602241H-Pyrr
1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986. S 18986 is a AMPA receptor positive modulator with EC2 (Concentration that doubles the intensity of the AMPA-induced current) of 35 μM.
价 格:¥电议型 号:T60224产 地:中国大陆
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T60006Aromatase inhibitor 23;化合物 Aromatase inhibitor 23Aromatase inhibitor 23
Aromatase inhibitor 23 is an inhibitor that target protein-protein interactions in RAD51 family of recombinases.
价 格:¥电议型 号:T60006产 地:中国大陆
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T5595Tropine;托品醇3alpha-Tropanol|||Pseudotropine;3alpha-Tropanol|||托品醇|||Pseudotropine
Tropine is a naturally-occurring tropane alkaloid extracted primarily from plants of the Solanaceae family. It serves as an intermediate in the synthesis of a variety of bioactive alkaloids.
价 格:¥电议型 号:T5595产 地:中国大陆
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T5587CGP71683 hydrochloride;盐酸CGP71683CGP71683A;CGP71683A|||盐酸CGP71683
CGP71683 hydrochloride (CGP71683A) is a competitive neuropeptide Y5 receptor antagonist (Ki: 1.3 nM) and shows no obvious activity at Y1 receptor (Ki >4000 nM) and Y2 receptor (Ki: 200 nM) in cell membranes.
价 格:¥电议型 号:T5587产 地:中国大陆
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T5479AMG 333;化合物AMG-333AMG-333;AMG-333
AMG 333 is TRPM8 antagonist with an IC50 of 13 nM,a Clinical Candidate for the Treatment of Migraine.
价 格:¥电议型 号:T5479产 地:中国大陆