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T15673KU 59403;化合物 T15673KU 59403
KU 59403 is an effective ATM inhibitor (IC50: 3 nM, 9.1 μM, and 10 μM for ATM, DNA-PK, and PI3K, respectively).
价 格:¥电议型 号:T15673产 地:中国大陆
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T15651KDU731;化合物 T15651KDU731
KDU731 is a promising drug candidate for the treatment of diarrhea caused by Cryptosporidium and meets a broad range of safety. KDU731is an orally active C. parvum inhibitor of PI4K (IC50: 25 nM). KDU731 blocks Cryptosporidium infection in vitro and in vivo.
价 格:¥电议型 号:T15651产 地:中国大陆
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T15573Inarigivir soproxil;化合物Inarigivir soproxilSB9200;SB9200
Inarigivir soproxil (SB9200) is an agonist of innate immunity. It also displays effective antiviral activity against resistant hepatitis C virus (HCV) variants (EC50s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype 1 HCV replicon systems).
价 格:¥电议型 号:T15573产 地:中国大陆
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T15473Heptaethylene glycol;化合物 T15473HO-PEG7-OH;HO-PEG7-OH
Heptaethylene glycol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15473产 地:中国大陆
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T15441GSK8573;化合物GSK8573GSK8573
GSK8573 is an inactive control compound for GSK2801. GSK8573 has binding activity to BRD9 (Kd of 1.04 μM).
价 格:¥电议型 号:T15441产 地:中国大陆
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T15432GSK256073;化合物GSK256073GSK256073
GSK256073 is an orally active GPR109A agonist. GSK256073 also is a long-lasting and non-flushing HCA2 (hydroxy-carboxylic acid receptor 2) full agonist (pEC50: 7.5). GSK256073 acutely improves glucose homeostasis via inhibition of lipolysis.
价 格:¥电议型 号:T15432产 地:中国大陆
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T1539Iloperidone;伊潘立酮HP 873;伊潘立酮|||HP 873
Iloperidone (HP 873) is an atypical antipsychotic agent that is used for treatment of schizophrenia.
价 格:¥电议型 号:T1539产 地:中国大陆
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T15373Gboxin;化合物GboxinGboxin
Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.
价 格:¥电议型 号:T15373产 地:中国大陆
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T15347FR167344 free base;化合物 T15347FR167344 free base
FR167344 free base is an orally active and nonpeptide antagonist of bradykinin receptor B2. FR167344 free base displays a high-affinity binding to the B2 receptor (IC50: 65 nM). It has no binding affinity for the B1 receptor.
价 格:¥电议型 号:T15347产 地:中国大陆
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T15273Fedovapagon;非多伐贡VA483|||A106483;VA483|||A106483
Fedovapagon (VA106483) is a selective and potent agonist of the vasopressin V2 receptor (V2R) that inhibits the growth of intersegmental vessels in zebrafish. Fedovapagon can be used to study overactive bladder, nocturia, and painful bladder syndromes.
价 格:¥电议型 号:T15273产 地:中国大陆
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T15173DSM265;化合物 DSM265PfSPZ;PfSPZ
DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity (IC50: 8.9 nM).DSM265 inhibits the growth of Pf3D7 parasites and can be used for the treatment and prophylaxis of malaria infections.
价 格:¥电议型 号:T15173产 地:中国大陆
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T15073DBCO-PEG4-NHS ester;化合物DBCO-PEG4-NHS esterDBCO-PEG4-NHS ester
DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].
价 格:¥电议型 号:T15073产 地:中国大陆
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T14973CITCO;化合物CITCOCITCO
CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors. CITCO is an imidazothiazole derivative and it also is a selective Constitutive androstane receptor (CAR) agonist.
价 格:¥电议型 号:T14973产 地:中国大陆
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T1497Liranaftate;利拉萘酯Piritetrate|||M-732;Piritetrate|||利拉萘酯|||M-732
Liranaftate (Piritetrate) is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is essential for cell membrane integrity. By preventing ergosterol synthesis and causing accumulation of squalene, this agent increases cell membrane permeability, cell leakage and eventually cell lysis.
价 格:¥电议型 号:T1497产 地:中国大陆
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T14934Cethromycin;化合物 T14934Abbott-195773|||ABT-773|||A-195773;Abbott-195773|||ABT-773|||A-195773
Cethromycin (ABT-773) is an antibiotic of ketolide.
价 格:¥电议型 号:T14934产 地:中国大陆
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T14919CDKI-73;化合物CDKI-73CDKI-73
CDKI-73 is a potent CDK9 inhibitor (Ki: 4 nM). It shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM).The inhibition of CDK9 induces apoptosis and potentiates the effect of cisplatin.
价 格:¥电议型 号:T14919产 地:中国大陆
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T14873Carboxyrhodamine 110-PEG3-Azide;化合物 T14873Carboxyrhodamine 110-PEG3-Azide
Carboxyrhodamine 110-PEG3-Azide is a polyethylene glycol (PEG)-based linker used for the synthesis of Proteolysis Targeting Chimeras (PROTACs) [1].
价 格:¥电议型 号:T14873产 地:中国大陆
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T14779BRD7389;化合物BRD7389BRD7389
BRD7389 is an inhibitor of RSK family kinase with IC50s of 1.5 μM, 2.4 μM, and 1.2 μM for RSK1, RSK2, and RSK3, respectively.
价 格:¥电议型 号:T14779产 地:中国大陆
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T14773Br-PEG4-OH;化合物 T14773Br-PEG4-OH
Br-PEG4-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14773产 地:中国大陆
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T14739Boc-NH-PEG2-NH-Boc;化合物 T14739Boc-NH-PEG2-NH-Boc
Boc-NH-PEG2-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14739产 地:中国大陆