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T16273Napsagatran hydrate;化合物 T16273Ro 46-6240/010 hydrate|||Ro 46-6240 hydrate;Ro 46-6240/010 hydrate|||R
Napsagatran hydrate is a novel and specific inhibitor of thrombin.
价 格:¥电议型 号:T16273产 地:中国大陆
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T16173N-(Amino-PEG5)-N-bis(PEG4-acid);化合物 T16173N-(Amino-PEG5)-N-bis(PEG4-acid)
N-(Amino-PEG5)-N-bis(PEG4-acid) is a PEG-based PROTAC linker employed for synthesizing PROTACs. It comprises an amino group with two terminal carboxylic acids[1].
价 格:¥电议型 号:T16173产 地:中国大陆
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T16112ML67-33化合物 T16112ML-67-33|||ML6733|||ML67 33
ML67-33 rapidly and reversibly affects K2P2.1 (TREK-1) (EC50s: 36.3 μM and 9.7 μM in cell-free and HEK293 cells, respectively). ML67-33 is a selective activator of temperature- and mechano-sensitive K2P channels.
价 格:¥电议型 号:T16112产 地:中国大陆
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T16092L-873724;化合物 T16092L-873724
L-873724 inhibits bone resorption. L-873724 is an effective, selective, and reversible non-basic cathepsin K inhibitor (IC50s: 0.2, 178, 264, and 5239 nM for cathepsin K, cathepsin S, cathepsin L, cathepsin B, respectively). L-873724 also shows an IC50 of 0.5 nM for rabbit cathepsin K.
价 格:¥电议型 号:T16092产 地:中国大陆
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T16090LMK-0773 FA;MK-0773 甲酸盐MK-0773 FA (606101-58-0 Free base);MK-0773 FA (606101-58-0 Free base)
MK-0773 FA (MK-0773 FA (606101-58-0 Free base)) is a selective androgen receptor modulator with an IC50 value of 6.6 nM for AR, which can be used for the prevention and treatment of cancer-related muscle wasting.
价 格:¥电议型 号:T16090L产 地:中国大陆
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T16090MK-0773;化合物 MK-0773PF-05314882;PF-05314882
MK-0773 (PF-05314882) is a selective androgen receptor modulator that binds to AR (IC50: 6.6 nM) for the study of diseases caused by endocrine abnormalities.
价 格:¥电议型 号:T16090产 地:中国大陆
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T16073Micronomicin;小诺霉素Gentamicin C2b|||Antibiotic XK-62-2|||Sagamicin;小诺霉素|||Gentamicin C2b|||Antibiotic
Micronomicin (Gentamicin C2b) is an antibiotic exhibiting antibacterial and bactericidal capacity.
价 格:¥电议型 号:T16073产 地:中国大陆
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T15973Mal-PEG1-acid;化合物 T15973Mal-PEG1-acid
Mal-PEG1-acid is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs)
价 格:¥电议型 号:T15973产 地:中国大陆
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T15818LY367385;化合物 T15818LY367385
LY367385 is a highly effective and selective mGluR1a antagonist. LY367385 has neuroprotective, anticonvulsant, and antiepileptic effects. Compared with > 100 μM for mGlu5a, LY367385 has an IC50 of 8.8 μM for inhibits of quisqualate-induced phosphoinositide (PI) hydrolysis.
价 格:¥电议型 号:T15818产 地:中国大陆
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T15804LY2452473;化合物 T15804LY2452473
LY2452473 is an orally bioavailable and selective androgen receptor modulator.
价 格:¥电议型 号:T15804产 地:中国大陆
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T15803LY223982化合物 T15803SKF107324|||CGS23131
LY223982 is an effective and specific inhibitor of the leukotriene B4 receptor (IC50: 13.2 nM). It also can against [3H]LTB4 binding to LTB4 receptor.
价 格:¥电议型 号:T15803产 地:中国大陆
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T15801LY210073;化合物 T15801LY210073
LY210073 is an antagonist of the Leukotriene B4 (LTB4) receptor (IC50: 6.2 nM).
价 格:¥电议型 号:T15801产 地:中国大陆
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T15773Lofepramine;洛非帕明Gamanil|||Amplit|||Leo 640|||Lopramine;Gamanil|||洛非帕明|||Amplit|||Leo 640|||Lopramine
Lofepramine (Leo 640) is a potent tricyclic antidepressant that is extensively metabolized to desipramine. It inhibits the serotonin and norepinephrine transporters by inhibiting neurons with Kd values of 70 and 5.4 nM, respectively, with weak antagonism of serotonin, histamine and muscarinic receptors.
价 格:¥电议型 号:T15773产 地:中国大陆
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T15736Leriglitazone;化合物 T15736Hydroxypioglitazone;Hydroxypioglitazone
Leriglitazone, a metabolite of pioglitazone, binds to the PPARγ C-terminal ligand-binding domain (Ki: 1.2 μM) and induces transcriptional efficacy of the PPARγ (EC50: 680 nM). Leriglitazone PioOH is a PPARγ agonist, stabilizes the PPARγ activation function-2 (AF-2) co-activator binding surface.
价 格:¥电议型 号:T15736产 地:中国大陆
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T15735Leptomycin B;来普霉素BCI 940|||LMB;CI 940|||LMB|||来普霉素B
Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue.
价 格:¥电议型 号:T15735产 地:中国大陆
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T15733Lemildipine;化合物 T15733NB-818|||NPK-1886;NB-818|||NPK-1886
Lemildipine is a new blocker of dihydropyridine calcium entry.
价 格:¥电议型 号:T15733产 地:中国大陆
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T15732Ribociclib succinate;瑞博西尼琥珀酸盐LEE011 succinate;LEE011 琥珀酸盐|||瑞博西尼琥珀酸盐|||LEE011 succinate
Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively). It also is over 1,000-fold less potent against the cyclin B/CDK1 complex.
价 格:¥电议型 号:T15732产 地:中国大陆
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T15731Ribociclib succinate hydrate化合物 T15731LEE011 succinate hydrate
Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively). It also is over 1,000-fold less potent against the cyclin B/CDK1 complex.
价 格:¥电议型 号:T15731产 地:中国大陆
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T15730Ribociclib hydrochloride瑞博西尼盐酸盐LEE011 hydrochloride|||瑞博西尼盐酸盐
Ribociclib hydrochloride is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively). It is over 1,000-fold less potent against the cyclin B/CDK1 complex.
价 格:¥电议型 号:T15730产 地:中国大陆