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T17352Acid-C1-PEG5-Boc；化合物Acid-C1-PEG5-BocAcid-C1-PEG5-Boc
Acid-C1-PEG5-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格：￥电议型 号：T17352产 地：中国大陆
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T17351Acetylene-linker-Val-Cit-PABC-MMAE；化合物 T17351AcetylenelinkerValCitPABCMMAE|||LCB14-0602|||Acetylene
Acetylene-linker-Val-Cit-PABC-MMAE (LCB14-0602) is a drug-linker conjugate for antibody-drug conjugates (ADCs) that combines the ADC linker (Acetylene-linker-Val-Cit-PABC) with the potent tubulin inhibitor MMAE.
价 格：￥电议型 号：T17351产 地：中国大陆
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T17350ACBI1；化合物ACBI1ACBI1
ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50s of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 can induce anti-proliferative effects and apoptosis.
价 格：￥电议型 号：T17350产 地：中国大陆
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T1735Lurasidone hydrochloride；盐酸鲁拉西酮Lurasidone HCl|||SM-13496 (Hydrochloride)|||SM-13496；Lurasidone HCl||
Lurasidone hydrochloride (Lurasidone HCl) is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotonin 5-HT2 receptor antagonist, serotonin 5-HT7 receptor antagonist, an antagonist of the adrenergic α2A and α2C receptors, as well as a partial serotonin 5-HT1A receptor agonist. It is used in the treatment of schizophrenia and bipolar disorder.
价 格：￥电议型 号：T1735产 地：中国大陆
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T1734LRizatriptan化合物 T1734LMK 462 free base|||Risatriptan
Rizatriptan is an agonist of the serotonin-1b and serotonin-1d receptor.
价 格：￥电议型 号：T1734L产 地：中国大陆
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T17349Ac4GlcNAlk；化合物 T17349Ac4GlcNAlk
Ac4GlcNAlk is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17349产 地：中国大陆
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T17348Ac4GalNAz；化合物Ac4GalNAzAc4GalNAz
Ac4GalNAz is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.
价 格：￥电议型 号：T17348产 地：中国大陆
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T173469-Decyn-1-ol；化合物 T173469-Decyn-1-ol
9-Decyn-1-ol is an alkyl/ether-based PROTAC linker suitable for synthesizing PROTACs. It serves as a conjugation agent to combine GDC-0068 and Lenalidomide, resulting in the formation of INY-03-041. INY-03-041 is a potent and highly selective pan-Akt degrader that operates through the PROTAC mechanism. It effectively inhibits Akt1, Akt2, and Akt3 with IC50 values of 2.0 nM, 6.8 nM, and 3.5 nM, respectively[1].
价 格：￥电议型 号：T17346产 地：中国大陆
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T173457-Octynoic acid；化合物 T173457-Octynoic acid
7-Octynoic acid (compound 42) serves as a PROTAC linker for synthesizing various PROTACs, which are composed of two distinct ligands joined by this linker. One ligand interacts with an E3 ubiquitin ligase, while the other binds to the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs selectively degrade target proteins[1].
价 格：￥电议型 号：T17345产 地：中国大陆
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T173447-O-(Cbz-N-amido-PEG4)-paclitaxel；化合物 T173447-O-(Cbz-N-amido-PEG4)-paclitaxel
7-O-(Cbz-N-amido-PEG4)-paclitaxel is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17344产 地：中国大陆
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T173437-O-(Amino-PEG4)-paclitaxel；化合物 T173437-O-(Amino-PEG4)-paclitaxel
7-O-(Amino-PEG4)-paclitaxel is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17343产 地：中国大陆
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T173426-O-2-Propyn-1-yl-D-galactose；化合物 T173426-O-2-Propyn-1-yl-D-galactose
6-O-2-Propyn-1-yl-D-galactose functions as an irreversible glycolinker, facilitating the attachment of cytotoxic drugs for applications in antibody-drug conjugation.
价 格：￥电议型 号：T17342产 地：中国大陆
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T173405-endo-BCN-pentanoic acid；化合物 T173405-endo-BCN-pentanoic acid
5-endo-BCN-pentanoic acid, an alkyl chain-based PROTAC linker, facilitates the synthesis of PROTACs[1].
价 格：￥电议型 号：T17340产 地：中国大陆
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T1734Rabeprazole Sulfide；雷贝拉唑相关物质ERabeprazole Related Compound E；雷贝拉唑相关物质E|||Rabeprazole Related Compound
Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors.
价 格：￥电议型 号：T1734产 地：中国大陆
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T17339(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin；化合物 T17339(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin
(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin is a polyethylene glycol (PEG)-based PROTAC linker utilized for the synthesis of PROTACs.
价 格：￥电议型 号：T17339产 地：中国大陆
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T17338(4-Oxo-4H-quinazolin-3-yl)-acetic acid；化合物 T17338(4-Oxo-4H-quinazolin-3-yl)-acetic acid
(4-Oxo-4H-quinazolin-3-yl)-acetic acid is an alkyl chain-derived PROTAC linker suitable for the synthesis of PROTACs[1].
价 格：￥电议型 号：T17338产 地：中国大陆
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T173374-N3Pfp-NHS ester；化合物 T173374-N3Pfp-NHS ester
4-N3Pfp-NHS ester is a noncleavable ADC linker utilized for synthesizing antibody-drug conjugates (ADCs).
价 格：￥电议型 号：T17337产 地：中国大陆
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T173364-(N-Boc-amino)-1,6-heptanedioic acid；化合物 T173364-(N-Boc-amino)-1,6-heptanedioic acid
4-(N-Boc-amino)-1,6-heptanedioic acid is an alkyl/ether-based linker, suitable for PROTAC synthesis [1].
价 格：￥电议型 号：T17336产 地：中国大陆
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T173354-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid；化合物 T173354-Methyl-4-(pyridin-2-yldisulfanyl)penta
4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid is a cleavable linker compound employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T17335产 地：中国大陆
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T173344-Methyl-4-(methyldisulfanyl)pentanoic acid；化合物 T173344-Methyl-4-(methyldisulfanyl)pentanoic acid
4-Methyl-4-(methyldisulfanyl)pentanoic acid is an ADC linker employed in the synthesis of antibody-drug conjugates (ADCs) that can be cleaved.
价 格：￥电议型 号：T17334产 地：中国大陆
