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T17732CL2A；化合物 T17732CL2A|||CL-2A|||CL2A；CL2A|||CL-2A|||CL2A
CL2A is a pH-sensitive, cleavable PEG8- and triazole-containing PABC-peptide-mc linker, characterized by its ability to induce a bystander effect. It forms a disulfide bond with an antibody at a cysteine residue. Labetuzumab govitecan utilizes this linker for its drug conjugation[1].
价 格：￥电议型 号：T17732产 地：中国大陆
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T17731LCL2A-SN-38 DCA 1279680-68-0(free base)；化合物CL2A-SN-38 DCACL2A-SN-38 DCA 1279680-68-0(free base)
CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC).. CL2A-SN-38 is composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A is a noncleavable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable t
价 格：￥电议型 号：T17731L产 地：中国大陆
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T17731CL2A-SN-38；化合物CL2A-SN-38CL2A|||CL2A SN 38|||bystander effect|||SN-38|||antitumor|||CL2A-SN-38|||Inhi
CL2A-SN-38 is a drug-linker conjugate consisting of SN-38, a potent DNA topoisomerase I inhibitor, and linker CL2A, for the manufacture of antibody drug conjugates (ADCs). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A is a nonclaevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulf
价 格：￥电议型 号：T17731产 地：中国大陆
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T17730CL2 Linker；化合物 T17730CL2 Linker
CL2 Linker is a cleavableADC linker. CL2-SN-38 and CL2A-SN-38 are equivalent in drug substitution (~6), cell binding (Kd ~1.2 nM), cytotoxicity (IC50 ~2.2 nM), and serum stability in vitro (t1/2 ~20 hours)[1][2].
价 格：￥电议型 号：T17730产 地：中国大陆
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T1773Afatinib Dimaleate；双马来酸盐阿法替尼BIBW2992|||Afatinib|||BIBW 2992MA2|||Afatinib (BIBW2992) Dimaleate；马来酸阿法
Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic activity.
价 格：￥电议型 号：T1773产 地：中国大陆
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T17673Boc-NH-PEG23-CH2CH2N3；化合物 T17673Boc-NH-PEG23-CH2CH2N3
Boc-NH-PEG23-CH2CH2N3 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17673产 地：中国大陆
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T1766Empagliflozin恩格列净BI 10773|||恩格列净
Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with more than 300-fold selectivity for SGLT-1/4/5/6. Empagliflozin is used for the treatment of type 2 diabetes.
价 格：￥电议型 号：T1766产 地：中国大陆
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T17573Biotin-PEG3-aldehyde；化合物 T17573Biotin-PEG3-aldehyde
Biotin-PEG3-aldehyde is a three-unit PEG linker with cleavable properties, specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T17573产 地：中国大陆
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T17473Azide-PEG9-amido-C4-Boc；化合物 T174735-(Azide-PEG9-ethylcarbamoyl)pentanoic t-butyl ester；5-(Azide-PEG9
Azide-PEG9-amido-C4-Boc is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T17473产 地：中国大陆
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T17399Amine-PEG-thiol (MW 3400)；化合物 T17399Amine-PEG-thiol (MW 3400)
Amine-PEG-thiol (MW 3400) is a polyethylene glycol (PEG)-based linker molecule containing an amine group and a thiol group. It serves as an essential component in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T17399产 地：中国大陆
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T17398Amine-PEG-thiol (MW 2000)；化合物 T17398Amine-PEG-thiol (MW 2000)
Amine-PEG-thiol (MW 2000) is a PEG-based PROTAC linker employed in PROTAC synthesis[1].
价 格：￥电议型 号：T17398产 地：中国大陆
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T17397Amine-PEG-CH2COOH (MW 2000)；化合物Amine-PEG-CH2COOH (MW 2000)Amine-PEG-CH2COOH (MW 5000)；Amine-PEG-CH2C
Amine-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格：￥电议型 号：T17397产 地：中国大陆
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T17396Amine-PEG-CH2COOH (MW 3400)；化合物 T17396Amine-PEG-CH2COOH (MW 3400)
Amine-PEG-CH2COOH (MW 3400) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T17396产 地：中国大陆
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T17395Amine-PEG-CH2COOH (MW 5000)；化合物 Amine-PEG-CH2COOH (MW 5000)Amine-PEG-CH2COOH (MW 5000)
Amine-PEG-CH2COOH (MW 5000) is a polyethylene glycol (PEG) derivative employed as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T17395产 地：中国大陆
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T17394Amine-PEG-amine (MW 5000)；化合物 T17394Amine-PEG-amine (MW 5000)
Amine-PEG-amine (MW 5000) is a polyethylene glycol (PEG) based linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].
价 格：￥电议型 号：T17394产 地：中国大陆
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T17393Amine-PEG-amine (MW 35000)；化合物 T17393Amine-PEG-amine (MW 35000)
Amine-PEG-amine (MW 35000), a PEG-based PROTAC linker, is utilized for the synthesis of PROTACs[1].
价 格：￥电议型 号：T17393产 地：中国大陆
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T17392Amine-PEG-amine (MW 3400)；化合物 T17392Amine-PEG-amine (MW 3400)
Amine-PEG-amine (MW 3400) is a polyethylene glycol (PEG) -based linker used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T17392产 地：中国大陆
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T17391Amine-PEG-amine (MW 20000)；化合物 T17391Amine-PEG-amine (MW 20000)
Amine-PEG-amine (MW 20000) is a polyethylene glycol (PEG)-based linker compound utilized in the synthesis of PROTACs.
价 格：￥电议型 号：T17391产 地：中国大陆
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T17390Amine-PEG-amine (MW 2000)；化合物 T17390Amine-PEG-amine (MW 2000)
Amine-PEG-amine (MW 2000) is a polyethylene glycol (PEG) derivative that functions as a linker for PROTAC synthesis. PROTACs are small molecules used for targeted protein degradation [1].
价 格：￥电议型 号：T17390产 地：中国大陆
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T1739WZ811；化合物WZ811WZ811
WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM).
价 格：￥电议型 号：T1739产 地：中国大陆
