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已选条件
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T18573Propargyl-PEG14-Boc;化合物 T18573Propargyl-PEG14-Boc
Propargyl-PEG14-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18573产 地:中国大陆
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T1853NMS-873;化合物NMS 873NMS-873
NMS-873 is a potent, selective allosteric VCP/p97 inhibitor.
价 格:¥电议型 号:T1853产 地:中国大陆
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T18473N3-PEG3-vc-PAB-MMAE;化合物 T18473N3PEG3vcPABMMAE|||N3-PEG3-vc-PAB-MMAE|||N-3-PEG3-vc-PAB-MMAE|||N3 PEG3
N3-PEG3-vc-PAB-MMAE, a drug-linker conjugate designed for Antibody-Drug Conjugates (ADC), features the integration of monomethyl auristatin E (MMAE), a tubulin inhibitor, via a 3-unit polyethylene glycol (PEG) linker. This compound demonstrates significant antitumor activity.
价 格:¥电议型 号:T18473产 地:中国大陆
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T18373N-(Amino-PEG4)-N-Biotin-PEG4-acid;化合物 T18373N-(Amino-PEG4)-N-Biotin-PEG4-acid
N-(Amino-PEG4)-N-Biotin-PEG4-acid is a PEG-based PROTAC linker that incorporates biotin for labeling purposes. This compound serves as a versatile tool in the synthesis of PROTACs[1].
价 格:¥电议型 号:T18373产 地:中国大陆
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T18273Mal-PEG12-DSPE;化合物 T18273Mal-PEG12-DSPE
Mal-PEG12-DSPE is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18273产 地:中国大陆
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T1821CGK733;化合物CGK 733CGK 733;CGK 733
CGK733 (CGK 733) is a potent and selective inhibitor of ATM/ATR.
价 格:¥电议型 号:T1821产 地:中国大陆
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T18173m-PEG25-acid;化合物 T18173m-PEG25-acid
m-PEG25-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18173产 地:中国大陆
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T18073Lipoamido-PEG12-acid;化合物 T18073Lipoamido-PEG12-acid
Lipoamido-PEG12-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18073产 地:中国大陆
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T1799Caspofungin Acetate;醋酸卡泊芬净L 743873|||Cancidas|||MK 0991|||L 743872;醋酸卡泊芬净|||L 743873|||Cancidas|||MK
Caspofungin Acetate (MK 0991) is the acetate salt of an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. This agent is active against Aspergillus and Candida species.
价 格:¥电议型 号:T1799产 地:中国大陆
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T17973Fmoc-NH-PEG30-CH2CH2COOH;化合物 T17973Fmoc-NH-PEG30-CH2CH2COOH
Fmoc-NH-PEG30-CH2CH2COOH is a PEGylation-based PROTAC linker employed for the synthesis of PROTACs[1].
价 格:¥电议型 号:T17973产 地:中国大陆
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T1792Regorafenib;瑞戈非尼BAY 73-4506|||Fluoro-Sorafenib;BAY 73-4506|||瑞戈非尼|||Fluoro-Sorafenib|||瑞格非尼
Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally active. Regorafenib has antitumor and anti-angiogenic activity.
价 格:¥电议型 号:T1792产 地:中国大陆
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T17873(4R,5S)-nutlin carboxylic acid;化合物 T17873(4R,5S)nutlin carboxylic acid|||(4R,5S) nutlin carboxylic a
(4R,5S)-Nutlin Carboxylic Acid (MDM2 Ligand 2), a Nutlin 3-based MDM2 ligand, can be conjugated to a protein-binding ligand via a linker to create PROTACs[1].
价 格:¥电议型 号:T17873产 地:中国大陆
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T17773DBCO-NHCO-PEG7-acid;化合物 T17773DBCO-NHCO-PEG7-acid
DBCO-NHCO-PEG7-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17773产 地:中国大陆
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T17739Cy5-PEG6-NHS ester;化合物 T17739Cy5-PEG6-NHS ester
Cy5-PEG6-NHS ester (chloride) is a PEG-based PROTAC linker utilized for PROTACs[1] synthesis.
价 格:¥电议型 号:T17739产 地:中国大陆
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T17738Cy5-PEG6-acid;化合物 T17738Cy5-PEG6-acid
Cy5-PEG6-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17738产 地:中国大陆
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T17737Cy5-PEG5-azide;化合物 T17737Cy5-PEG5-azide
Cy5-PEG5-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17737产 地:中国大陆
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T17736Cy5-PEG5-amine hydrochloride;化合物 T17736Cy5-PEG5-amine hydrochloride
Cy5-PEG5-amine (hydrochloride) is a PEG-derived PROTAC linker employed for PROTAC synthesis[1].
价 格:¥电议型 号:T17736产 地:中国大陆
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T17735Cy5-PEG4-acid;化合物 T17735Cy5-PEG4-acid
Cy5-PEG4-acid (chloride) serves as a PEG-based PROTAC linker, suitable for synthesizing PROTACs[1].
价 格:¥电议型 号:T17735产 地:中国大陆
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T17734Cy5-PEG3-azide;化合物 T17734Cy5-PEG3-azide
Cy5-PEG3-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17734产 地:中国大陆
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T17733ATRA-hydroxyimino;化合物 T17733CRABP-II ligand 1;CRABP-II ligand 1
ATRA-hydroxyimino, also known as CRABP-II ligand 1, is a chemical compound derived from Retinoic acid (ATRA). This compound binds to the cIAP1 ligand, specifically Bestatin, through a linker, resulting in the formation of a complex called SNIPER. The purpose of this complex is to degrade CRABP-II within IMR-32 cells[1].
价 格:¥电议型 号:T17733产 地:中国大陆