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T17370Ald-Ph-amido-PEG24-acid;化合物 T17370Ald-Ph-amido-PEG24-acid
Ald-Ph-amido-PEG24-acid is a polyethylene glycol (PEG)-based linker used for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T17370产 地:中国大陆
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T1737Genistein;染料木素NPI 031L;NPI 031L|||三叶草|||染料木素|||金雀异黄酮
Genistein (NPI 031L) is an isoflavonoid derived from soy products. It inhibits protein-tyrosine kinase and topoisomerase-II (DNA TOPOISOMERASES, TYPE II), with antineoplastic and antitumor activities.
价 格:¥电议型 号:T1737产 地:中国大陆
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T17369Ald-Ph-amido-PEG23-OPSS;化合物 T17369Ald-Ph-amido-PEG23-OPSS
Ald-Ph-amido-PEG23-OPSS is a cleavable 23-unit polyethylene glycol linker commonly employed for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T17369产 地:中国大陆
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T17368Ald-Ph-amido-C2-PEG3-azide;化合物 T17368Ald-Ph-amido-C2-PEG3-azide
Ald-Ph-amido-C2-PEG3-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17368产 地:中国大陆
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T17367Ald-CH2-PEG8-azide;化合物 T17367Ald-CH2-PEG8-azide
Ald-CH2-PEG8-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17367产 地:中国大陆
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T17366Ald-CH2-PEG10-Boc;化合物 T17366Ald-CH2-PEG10-Boc
Ald-CH2-PEG10-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17366产 地:中国大陆
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T17365Ala-Ala-Asn-PAB;化合物 T17365Ala-Ala-Asn-PAB
Ala-Ala-Asn-PAB is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T17365产 地:中国大陆
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T17364AhR Ligand-Linker Conjugates 1;化合物 T17364E3 Ligase Ligand-Linker Conjugates 57;E3 Ligase Ligand-Link
AhR Ligand-Linker Conjugates 1, also known as E3 Ligase Ligand-Linker Conjugates 57, is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a SNIPER linker. It is specifically designed to be used in the development of SNIPER[1].
价 格:¥电议型 号:T17364产 地:中国大陆
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T17363β-Naphthoflavone-CH2-OH;化合物 T17363β-NF-CH2-OH;β-NF-CH2-OH
β-Naphthoflavone-CH2-OH (β-NF-CH2-OH) serves as an AhR E3 ligase ligand, forming chimeric molecules when connected to a protein ligand through a linker, resulting in PROTACs or SNIPERs (e.g., β-naphthoflavone-JQ1). These chimeric molecules recruit the AhR E3 ligase complex by incorporating AhR ligands. By inducing ubiquitination-mediated degradation, PROTACs effectively target and degrade cancer-promoting proteins [1].
价 格:¥电议型 号:T17363产 地:中国大陆
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T17362Acrylate-PEG-OH (MW 5000);化合物 T17362Acrylate-PEG-OH (MW 5000)
Acrylate-PEG-OH (MW 5000) is a Polyethylene Glycol (PEG)-based linker compound primarily utilized in PROTAC synthesis[1].
价 格:¥电议型 号:T17362产 地:中国大陆
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T17361Acrylate-PEG-OH (MW 3400);化合物 T17361Acrylate-PEG-OH (MW 3400)
Acrylate-PEG-OH (MW 3400) is a polyethylene glycol (PEG) derived PROTAC linker compound, which finds application in the synthesis of PROTACs[1].
价 格:¥电议型 号:T17361产 地:中国大陆
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T17360Acrylate-PEG-OH (MW 10000);化合物 T17360Acrylate-PEG-OH (MW 10000)
Acrylate-PEG-OH (MW 10000) is a Polyethylene Glycol (PEG) derived PROTAC linker utilized for synthesizing PROTACs[1].
价 格:¥电议型 号:T17360产 地:中国大陆
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T1736Apixaban阿哌沙班阿哌沙班|||BMS-562247-01
Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and preventing the formation of cross-linked fibrin clots.
价 格:¥电议型 号:T1736产 地:中国大陆
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T17359Acrylate-PEG-NH2 (MW 2000);化合物 T17359Acrylate-PEG-NH2 (MW 2000)
Acrylate-PEG-NH2 (MW 2000) is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker, employed for the synthesis of PROTACs [1].
价 格:¥电议型 号:T17359产 地:中国大陆
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T17358Acrylate-PEG-NH2 (MW 10000);化合物 T17358Acrylate-PEG-NH2 (MW 10000)
Acrylate-PEG-NH2 (MW 10000) is a polyethylene glycol (PEG)-based linker utilized in the synthesis of PROTACs[1].
价 格:¥电议型 号:T17358产 地:中国大陆
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T17357AcLys-PABC-VC-Aur0101;化合物 T17357AcLys PABC VC Aur0101|||AcLys-PABC-VC-Aur-0101|||AcLysPABCVCAur0101|
AcLys-PABC-VC-Aur0101 is a drug-linker conjugate for anti-CXCR4 ADC with potent antitumor activity, comprising the auristatin microtubule inhibitor Aur0101, connected through the cleavable linker AcLys-PABC-VC[1].
价 格:¥电议型 号:T17357产 地:中国大陆
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T17356Acid-propionylamino-Val-Cit-OH;化合物 T17356Acid-propionylamino-Val-Cit-OH
Acid-propionylamino-Val-Cit-OH is a cleavable linker commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T17356产 地:中国大陆
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T17355Acid-PEG4-S-PEG4-acid;化合物 T17355Acid-PEG4-S-PEG4-acid
Acid-PEG4-S-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17355产 地:中国大陆
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T17354Acid-PEG25-NHS ester;化合物 T17354Acid-PEG25-NHS ester
Acid-PEG25-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17354产 地:中国大陆
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T17353Acid-PEG13-NHS ester;化合物 T17353Acid-PEG13-NHS ester
Acid-PEG13-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17353产 地:中国大陆