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已选条件
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T14738Boc-NH-PEG2-CH2COOH;化合物 T14738Boc-NH-PEG2-CH2COOH
Boc-NH-PEG2-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14738产 地:中国大陆
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T14737Boc-NH-PEG2-CH2CH2COOH;化合物 T14737Boc-NH-PEG2-CH2CH2COOH
Boc-NH-PEG2-CH2CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14737产 地:中国大陆
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T14736Boc-NH-PEG2-C2-NHS ester;化合物 T14736Boc-NH-PEG2-C2-NHS ester
Boc-NH-PEG2-C2-NHS ester is an alkyl/ether-derived PROTAC linker employed for the synthesis of PROTACs[1].
价 格:¥电议型 号:T14736产 地:中国大陆
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T14735Boc-NH-PEG1-CH2COOH;化合物 T14735Boc-NH-PEG-1-CH2COOH|||BocNHPEG1CH2COOH|||Boc NH PEG1 CH2COOH|||Boc-NH
Boc-NH-PEG1-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14735产 地:中国大陆
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T14734Boc-NH-PEG1-CH2CH2COOH;化合物 T14734Boc-NH-PEG1-CH2CH2COOH
Boc-NH-PEG1-CH2CH2COOH is a cleavable ADC linker, possessing one unit of PEG, that can be utilized for the synthesis of antibody-drug conjugates (ADCs) and PROTACs. Additionally, it serves as a PEG- and Alkyl/ether-based PROTAC linker [1][2].
价 格:¥电议型 号:T14734产 地:中国大陆
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T14733Boc-NH-ethyl-SS-propionic acid;化合物 T14733Boc-NH-ethyl-SS-propionic acid
Boc-NH-ethyl-SS-propionic acid is an ADC linker compound employed for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14733产 地:中国大陆
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T14732Boc-N-PEG5-C2-NHS ester;化合物 T14732Boc-N-PEG5-C2-NHS ester
Boc-N-PEG5-C2-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14732产 地:中国大陆
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T14731Boc-N-PEG1-C2-NHS ester;化合物 T14731Boc-N-PEG1-C2-NHS ester
Boc-N-PEG1-C2-NHS ester, a PEG-based linker, finds utility in PROTAC synthesis[1].
价 格:¥电议型 号:T14731产 地:中国大陆
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T14730Boc-N-Amido-PEG4-propargyl;化合物 T14730Boc-N-Amido-PEG4-propargyl
Boc-N-Amido-PEG4-propargyl is a PEG-based PROTAC linker utilized for synthesizing PROTACs[1].
价 格:¥电议型 号:T14730产 地:中国大陆
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T1473Trilostane;曲洛司坦Win 24540;曲洛斯坦|||Win 24540|||曲洛司坦
Trilostane (Win 24540) is a synthetic derivative of androstane with adrenocortical suppressive properties. Trilostane reversibly inhibits 3 beta-hydroxysteroid dehydrogenase delta 5-4 isomerase in the adrenal cortex.
价 格:¥电议型 号:T1473产 地:中国大陆
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T14673BMS 299897;化合物BMS 299897BMS 299897
BMS 299897 is a sulfonamide γ-secretase inhibitor. It has an IC50 of 7 nM for Aβ production inhibition in HEK293 cells stably overexpressing amyloid precursor protein (APP).
价 格:¥电议型 号:T14673产 地:中国大陆
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T14614Biperiden Hydrochloride;盐酸比哌立登KL 373 (Hydrochloride);KL 373 (Hydrochloride)|||盐酸比哌立登
Biperiden Hydrochloride (KL 373 Hydrochloride) is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker and it is used for the adjunctive treatment of all forms of Parkinson´s disease (postencephalitic, idiopathic, and arteriosclerotic)[1]. Target: M1 receptors Biperiden is an antiparkinsonian agent of the anticholinergic type. Biperiden has an atropine-like blocking effect on all peripheral structures which are parasympathetic-innervate and it also has a pr
价 格:¥电议型 号:T14614产 地:中国大陆
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T14573Bimosiamose disodium;化合物 T14573TBC-1269Z;TBC-1269Z
Bimosiamose disodium has anti-inflammatory effects[1]. Bimosiamose disodium (TBC-1269Z) is a nonoligosaccharide pan-selectin inhibitor with IC50s of 88 μM, 20 μM, and 86 μM for E-selectin, P-selectin, and L-selectin, respectively.
价 格:¥电议型 号:T14573产 地:中国大陆
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T1452Axitinib;阿昔替尼AG-013736;AG-013736|||阿昔替尼|||阿西替尼
Axitinib (AG-013736) is an orally bioavailable tyrosine kinase inhibitor with IC50s of 0.1, 0.2, 0.1-0.3, 1.7, 1.6 nM for VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ, respectively.
价 格:¥电议型 号:T1452产 地:中国大陆
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T14494Balovaptan;化合物BalovaptanRG7314;RG7314
Balovaptan (RG7314) is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors. It is used for the research of autism.
价 格:¥电议型 号:T14494产 地:中国大陆
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T14473Azido-PEG8-acid;化合物 T14473Azido-PEG8-acid
Azido-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14473产 地:中国大陆
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T14373AZD2423;化合物 T14373AZD2423
AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator and it has an IC50 of 1.2 nM for CCR2 Ca2+ flux [1][2][3].
价 格:¥电议型 号:T14373产 地:中国大陆
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T14307Aplaviroc;阿拉韦洛GSK 873140|||ONO-4128|||GW 873140|||AK 602;GSK 873140|||ONO-4128|||GW 873140|||AK 602
Aplaviroc (AK 602) is a novel and highly potent CCR5 antagonist with antiviral activity that inhibits HIV-1Ba-L, HIV-1JRFL, and HIV-1MOKW and can be used in the study of human immunodeficiency virus infection.
价 格:¥电议型 号:T14307产 地:中国大陆
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T14273Aminooxy-PEG4-C2-Boc;化合物 T14273Aminooxy-PEG4-C2-Boc
Aminooxy-PEG4-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14273产 地:中国大陆
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T14203AM-8735;化合物 T14203AM-8735
AM-8735 is an inhibitor of MDM2 ( IC50: 25 nM).
价 格:¥电议型 号:T14203产 地:中国大陆