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T17891cIAP1 Ligand-Linker Conjugates 2;化合物 T17891E3 ligase Ligand-Linker Conjugates 37;E3 ligase Ligand-Li
cIAP1 Ligand-Linker Conjugates 2 is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a PROTAC linker. This compound is particularly useful in the design of SNIPERs [1].
价 格:¥电议型 号:T17891产 地:中国大陆
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T17890cIAP1 Ligand-Linker Conjugates 2 Hydrochloride;化合物 T17890E3 ligase Ligand-Linker Conjugates 37 Hydro
cIAP1 Ligand-Linker Conjugates 2 Hydrochloride is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. It is utilized in the creation of SNIPERs[1].
价 格:¥电议型 号:T17890产 地:中国大陆
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T1789Obeticholic Acid;奥贝胆酸INT-747|||6-Ethylchenodeoxycholic acid|||6-ECDCA;奥贝胆酸|||INT-747|||6-Ethylchenod
Obeticholic Acid (6-ECDCA) is a Farnesoid X Receptor Agonist. The mechanism of action of obeticholic acid is as a Farnesoid X Receptor Agonist.
价 格:¥电议型 号:T1789产 地:中国大陆
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T17889cIAP1 Ligand-Linker Conjugates 14;化合物 T17889E3 ligase Ligand-Linker Conjugates 36;E3 ligase Ligand-L
cIAP1 Ligand-Linker Conjugates 14 consist of an IAP ligand that targets the E3 ubiquitin ligase and a PROTAC linker. These conjugates, known as cIAP1 Ligand-Linker Conjugates 14, are used in the development of SNIPERs[1].
价 格:¥电议型 号:T17889产 地:中国大陆
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T17888cIAP1 Ligand-Linker Conjugates 6 hydrochloride;化合物 T17888E3 ligase Ligand-Linker Conjugates 35 hydro
cIAP1 Ligand-Linker Conjugates 6 hydrochloride is a compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. It is utilized for the purpose of designing SNIPERs[1].
价 格:¥电议型 号:T17888产 地:中国大陆
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T17887cIAP1 Ligand-Linker Conjugates 15;化合物 T17887E3 ligase Ligand-Linker Conjugates 34;E3 ligase Ligand-L
cIAP1 Ligand-Linker Conjugates 15 consists of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 15, is suitable for the development of SNIPERs[1].
价 格:¥电议型 号:T17887产 地:中国大陆
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T17886cIAP1 Ligand-Linker Conjugates 15 hydrochloride;化合物 T17886E3 ligase Ligand-Linker Conjugates 34 hydr
cIAP1 Ligand-Linker Conjugates 15 hydrochloride is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is useful in the development of SNIPERs[1].
价 格:¥电议型 号:T17886产 地:中国大陆
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T17885cIAP1 Ligand-Linker Conjugates 11;化合物 T17885E3 ligase Ligand-Linker Conjugates 33;E3 ligase Ligand-L
cIAP1 Ligand-Linker Conjugates 11 is a chemical compound that combines an IAP ligand specifically designed for the E3 ubiquitin ligase with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 11, is useful in the development of SNIPERs[1], allowing for the targeted degradation of proteins.
价 格:¥电议型 号:T17885产 地:中国大陆
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T17884cIAP1 Ligand-Linker Conjugates 11 Hydrochloride;化合物 T17884E3 ligase Ligand-Linker Conjugates 33 Hydr
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride is a chemical compound consisting of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. It is primarily utilized in the development of SNIPERs, a molecular tool for targeted protein degradation[1].
价 格:¥电议型 号:T17884产 地:中国大陆
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T17883Pomalidomide-PEG3-C2-NH2;化合物Pomalidomide-PEG3-C2-NH2Cereblon Ligand-Linker Conjugates 5|||E3 ligase
Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide based cereblon ligand and 3-unit PEG linker.
价 格:¥电议型 号:T17883产 地:中国大陆
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T17882Pomalidomide-PEG3-C2-NH2 (TFA);化合物 T17882Cereblon Ligand-Linker Conjugates 5 (TFA)|||E3 ligase Ligan
Pomalidomide-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
价 格:¥电议型 号:T17882产 地:中国大陆
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T17881(S,R,S)-AHPC-C10-NH2;化合物(S,R,S)-AHPC-C10-NH2VH032-C10-NH2;VH032-C10-NH2
(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is a synthesized E3 ligase ligand-linker conjugate, comprising the (S,R,S)-AHPC-based VHL ligand and a linker, designed for BET-targeted PROTAC applications.
价 格:¥电议型 号:T17881产 地:中国大陆
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T17880E3 ligase Ligand 9;化合物 T17880E3 ligase Ligand 9
E3 ligase Ligand 9 is a compound that serves as a ligand for E3 ubiquitin ligase. It can be linked to the protein ligand through a linker, forming PROTACs or SNIPERs. These PROTACs are known to induce the degradation of cancer-promoting proteins through ubiquitination-mediated mechanisms[1].
价 格:¥电议型 号:T17880产 地:中国大陆
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T1788Tazemetostat;化合物EPZ6438E-7438|||EPZ6438;E-7438|||EPZ6438
Tazemetostat (EPZ6438) is a histone methyltransferase EZH2 inhibitor (IC50=11 nM) that is orally active, selective, and SAM-competitive. Tazemetostat exhibits antitumor activity and may be used for the treatment of epithelioid sarcoma/follicular lymphoma.
价 格:¥电议型 号:T1788产 地:中国大陆
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T17879E3 ligase Ligand 8;化合物E3 ligase Ligand 8E3 ligase Ligand 8
E3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. The E3 ligase Ligand 8 can be linked to protein ligands through linkers to form PROTACs, which are inducers of ubiquitination-mediated degradation of cancer-promoting proteins.
价 格:¥电议型 号:T17879产 地:中国大陆
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T17878Lenalidomide-C4-NH2 hydrochloride;化合物 T17878Cereblon ligand 1 hydrochloride|||E3 ligase Ligand-Linke
Lenalidomide-C4-NH2 hydrochloride is a Cereblon ligand derived from Lenalidomide. It serves as a recruiting agent for the CRBN protein. The compound, known as PROTAC (Compound 24), can be formed by linking Lenalidomide-C4-NH2 hydrochloride to the ligand for the protein. It exhibits inhibitory effects with IC50s of 0.98 nM and 13.7 nM against the growth of RS4;11 and MOLM-13 acute leukemia cell lines, respectively[1].
价 格:¥电议型 号:T17878产 地:中国大陆
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T17877VH032-cyclopropane-F;化合物T17877VHL ligand 3|||E3 ligase Ligand 19|||Phenolic VH101;VHL ligand 3|||E3
VH032-cyclopropane-F (Phenolic VH101) is a VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein by a linker to form PROTACs. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4.
价 格:¥电议型 号:T17877产 地:中国大陆
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T17876E3 ligase Ligand 18;化合物 T17876E3 ligase Ligand 18
E3 ligase Ligand 18 is a ligand that binds to E3 ubiquitin ligase, and it can be chemically attached to a protein ligand through a linker to create PROTACs. The resulting PROTACs function as inducers of ubiquitination-mediated degradation, targeting cancer-promoting proteins[1].
价 格:¥电议型 号:T17876产 地:中国大陆
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T17875Pomalidomide-C2-NH2;化合物T17875Cereblon Ligand-Linker Conjugates 15|||4-[(2-Aminoethyl)amino]-2-(2,6-d
Pomalidomide-C2-NH2 (4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione) is a synthesized E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a linker.
价 格:¥电议型 号:T17875产 地:中国大陆
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T17874Nutlin carboxylic acid;化合物 T17874MDM2 ligand 1|||E3 ligase Ligand 16;MDM2 ligand 1|||E3 ligase Ligan
Nutlin Carboxylic Acid (MDM2 ligand 1), derived from Nutlin 3, serves as an MDM2 ligand. It can be attached to a protein ligand via a linker to create PROTACs[1].
价 格:¥电议型 号:T17874产 地:中国大陆