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T17818Thalidomide-O-amido-C4-NH2;化合物 T17818E3 Ligase Ligand-Linker Conjugates 19|||Cereblon Ligand-Linker
Thalidomide-O-amido-C4-NH2 (Cereblon Ligand-Linker Conjugates 6) is a synthesized ligand-linker conjugate that combines a Thalidomide-based cereblon ligand with a linker. It functions as an E3 ligase ligand-linker conjugate and finds applications in the synthesis of PROTACs[1].
价 格:¥电议型 号:T17818产 地:中国大陆
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T17817DBCO-(PEG)3-VC-PAB-MMAE;化合物 T17817DBCO (PEG)3 VC PAB MMAE|||DBCO-(PEG)3-VC-PAB-MMAE|||DBCO(PEG)3VCPA
DBCO-(PEG)3-VC-PAB-MMAE is a chemical compound where monomethyl auristatin E (MMAE), a potent tubulin inhibitor acting as a toxin payload in antibody-drug conjugates, is conjugated to a DBCO-(PEG)3-vc-PAB linker.
价 格:¥电议型 号:T17817产 地:中国大陆
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T17816DBCO-Val-Cit-PABC-PNP;化合物 T17816DBCO Val Cit PABC PNP|||DBCOValCitPABCPNP|||DBCO-Val-Cit-PABC-PNP;DB
DBCO-Val-Cit-PABC-PNP is a cleavable linker for antibody-drug conjugate (ADC) synthesis[1].
价 格:¥电议型 号:T17816产 地:中国大陆
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T17815DBCO-Val-Cit-PABC-OH;化合物 T17815DBCO-Val-Cit-PABC-OH
DBCO-Val-Cit-PABC-OH is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs) [1].
价 格:¥电议型 号:T17815产 地:中国大陆
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T17814DBCO-Val-Cit-OH;化合物 T17814DBCO-Val-Cit-OH
DBCO-Val-Cit-OH, a cleavable linker compound, finds utility in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T17814产 地:中国大陆
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T17813DBCO-SS-PEG4-Biotin;化合物 T17813DBCO-SS-PEG4-Biotin
DBCO-SS-PEG4-Biotin is a cleavable link mid-functional ADC linker composed of a 4-unit PEG moiety. It finds utility in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T17813产 地:中国大陆
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T17812DBCO-SS-amine;化合物 T17812DBCO-SS-amine
DBCO-SS-amine is a cleavable linker vital in ADC synthesis. DBCO-SS-amine joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
价 格:¥电议型 号:T17812产 地:中国大陆
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T17811DBCO-SS-aldehyde;化合物 T17811DBCO-SS-aldehyde
DBCO-SS-aldehyde is an ADC linker employed for ADC synthesis[1]. This cleavable linker is designed to facilitate the conjugation of antibodies and drugs, resulting in antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T17811产 地:中国大陆
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T17810DBCO-PEG9-NH-Boc;化合物 T17810DBCO-PEG9-NH-Boc
DBCO-PEG9-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17810产 地:中国大陆
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T1781GW9508;化合物GW 9508GW 9508;GW 9508
GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.
价 格:¥电议型 号:T1781产 地:中国大陆
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T1780LParecoxib sodium帕瑞昔布钠SC 69124A|||SC-69124A|||帕瑞昔布钠|||SC69124A|||Dynastat
Parecoxib is a cyclooxygenase-2 inhibitor used for the short-term treatment of postoperative pain in adults. Parecoxib is a water-soluble and injectable prodrug of valdecoxib. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib and rofecoxib. ketorolac has a much higher gastrointestinal toxicity profile compared to most other nonsteroidal anti-inflammatory drugs including ibuprofen and Naprosyn.
价 格:¥电议型 号:T1780L产 地:中国大陆
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T17809DBCO-PEG9-DBCO;化合物 T17809DBCO-PEG9-DBCO
DBCO-PEG9-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17809产 地:中国大陆
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T17808DBCO-PEG9-amine;化合物 T17808DBCO-PEG9-amine
DBCO-PEG9-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17808产 地:中国大陆
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T17807DBCO-PEG8-NHS ester;化合物 T17807DBCO-PEG8-NHS ester
DBCO-PEG8-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17807产 地:中国大陆
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T17806DBCO-PEG8-acid;化合物 T17806DBCO-PEG8-acid
DBCO-PEG8-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17806产 地:中国大陆
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T17805DBCO-PEG6-amine;化合物 T17805DBCO-PEG6-amine
DBCO-PEG6-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17805产 地:中国大陆
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T17804DBCO-PEG5-DBCO;化合物 T17804DBCO-PEG5-DBCO
DBCO-PEG5-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17804产 地:中国大陆
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T17802DBCO-PEG4-VC-PAB-DMEA-PNU-159682;化合物 T17802DBCO-PEG4-VC-PAB-DMEA-PNU-159682|||DBCO PEG4 VC PAB DMEA
DBCO-PEG4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for antibody-drug conjugates (ADC), comprises the ADC linker DBCO-PEG4-VC-PAB and the potent ADC cytotoxin DMEA-PNU-159682. The cytotoxin includes metabolites of nemorubicin (MMDX) from liver microsomes and the ADC cytotoxin PNU-159682[1].
价 格:¥电议型 号:T17802产 地:中国大陆
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T17801DBCO-PEG4-VA-PBD;化合物 T17801DBCO-PEG4-VA-PBD
DBCO-PEG4-VA-PBD is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T17801产 地:中国大陆
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T17800DBCO-PEG4-triethoxysilane;化合物 T17800DBCO-PEG4-triethoxysilane
DBCO-PEG4-triethoxysilane is a polyethylene glycol (PEG)-based linker compound that serves as an efficient building block for the synthesis of PROTACs. These PROTACs are small molecules designed to selectively target and degrade specific proteins of interest[1].
价 格:¥电议型 号:T17800产 地:中国大陆