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T1671Mirabegron;米拉贝隆YM178;YM178|||米拉贝隆
Mirabegron (YM178) is a beta-3 adrenergic agonist that is used for treatment of overactive bladder syndrome.
价 格:¥电议型 号:T1671产 地:中国大陆
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T16678PSN632408;化合物 T16678PSN632408
PSN632408 is an optimized agonist of GPR119 receptors that display similar potency to OEA at both recombinant mouse and human GPR119 receptors (EC50: 5.6 and 7.9 uM, respectively).
价 格:¥电议型 号:T16678产 地:中国大陆
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T16578PRN694;化合物 T16578PRN694
PRN694 shows extended target residence time on ITK and RLK, enabling durable attenuation of effector cells in vitro and in vivo. PRN694 is an irreversible, highly selective, and effective covalent interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) dual inhibitor (IC50s: 0.3 nM and 1.4 nM, respectively).
价 格:¥电议型 号:T16578产 地:中国大陆
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T16506PF-4878691;化合物PF-48786913M-852A;3M-852A
PF-4878691 (3M-852A) is an effective and selective Toll-like receptor 7 agonists modelled. It is used to dissociate its antiviral and inflammatory activities.
价 格:¥电议型 号:T16506产 地:中国大陆
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T16505PF-4778574;化合物 T16505PF-4778574
PF-4778574 is a positive AMPA receptor allosteric modulation (EC50: 45 to 919 nM in different cells).
价 格:¥电议型 号:T16505产 地:中国大陆
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T1649Tenofovir;替诺福韦PMPA|||TDF|||GS 1278;替诺福韦|||泰诺福韦|||PMPA|||TDF|||GS 1278
Tenofovir (GS 1278) is an adenine analog REVERSE TRANSC-RIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIVIRAL AGENTS, due to the emergence of ANTIVIRAL DRUG RESISTANCE when it is used alone.
价 格:¥电议型 号:T1649产 地:中国大陆
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T16478PF-04447943化合物PF-04447943PF 04447943|||Edelinontrine|||PF04447943
PF-04447943 (Edelinontrine) is a potent and selective phosphodiesterase 9A inhibitor with an IC50 of 12 nM, which is 78-fold more selective than that used for other PDE family members (IC50>1000 nM).PF-04447943 exhibits anti-inflammatory activity, attenuates inflammatory responses by inhibiting oxidative stress, inflammation, and modulating T-cell polarization, and may be useful for research on sickle cell anemia.
价 格:¥电议型 号:T16478产 地:中国大陆
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T16446PD 407824化合物 PD 407824PD-407824
PD 407824 is a chemical BMP sensitiser that promotes increased cellular sensitivity to subthreshold amounts of BMP4.PD 407824 is a potent inhibitor of the checkpoint kinases Chk1 and WEE1 (IC50s: 47 and 97 nM, respectively).
价 格:¥电议型 号:T16446产 地:中国大陆
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T16439PC786;化合物 T16439PC786
PC786 shows effective antiviral activity against RSV-A (IC50 <0.09 to 0.71 nM) and RSV-B (IC50, 1.3 to 50.6 nM). PC786 is an inhaled respiratory syncytial virus L protein polymerase inhibitor.
价 格:¥电议型 号:T16439产 地:中国大陆
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T16378Ogerin;化合物OgerinG Protein-Coupled Receptor 68|||Inhibitor|||TGF-β|||inhibit|||Ogerin|||fibroblasts||
Ogerin is a selective GPR68 positive allosteric modulator (pEC50: 6.83). Ogerin blocks recall in fear conditioning in mice. Ogerin displays inverse agonist and antagonist activity (Ki, 220 nM) at A2A receptor and weak antagonist activity (Ki, 736 nM) at 5-HT2B receptor.
价 格:¥电议型 号:T16378产 地:中国大陆
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T16366NVR 3-778;化合物NVR 3-778NVR 3-778
NVR 3-778 is a first-in-Class and oral bioavailable HBV CAM belonging to the SBA class It has anti-HBV activity.
价 格:¥电议型 号:T16366产 地:中国大陆
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T16356Glyoxalic acid化合物 T16356Oxalaldehydic acid|||NSC 27785|||Formylformic acid
Glyoxalic acid is an organic compound. It is both an aldehyde and a carboxylic acid.
价 格:¥电议型 号:T16356产 地:中国大陆
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T16355NSC781406;化合物NSC781406NSC781406
NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).
价 格:¥电议型 号:T16355产 地:中国大陆
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T16350NSC-87877;化合物NSC-87877NSC-87877
NSC-87877 is an effective inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (IC50=0.318 μM, 0.355 μM of shp2 and shp1, respectively).It also inhibits dual-specificity phosphatase 26 (DUSP26).
价 格:¥电议型 号:T16350产 地:中国大陆
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T16278NCX1022;化合物 T16278NCX1022
NCX1022 is a NO-releasing derivative of Hydrocortisone. It is the most widely used anti-inflammatory drug for the treatment of skin inflammation.
价 格:¥电议型 号:T16278产 地:中国大陆
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T1623Lopinavir;洛匹那韦ABT-378;ABT-378|||洛匹那韦
Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir is less affected by binding to serum proteins than the structurally-related drug ritonavir.
价 格:¥电议型 号:T1623产 地:中国大陆
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T16178N-(Azido-PEG2)-N-Boc-PEG3-Boc;化合物 T16178N-(Azido-PEG2)-N-Boc-PEG3-Boc
N-(Azido-PEG2)-N-Boc-PEG3-Boc is a PEG-based PROTAC linker, suitable for the synthesis of PROTACs[1].
价 格:¥电议型 号:T16178产 地:中国大陆
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T1617Enrofloxacin;恩诺沙星BAY-Vp2674|||PD160788;恩诺沙星|||BAY-Vp2674|||PD160788
Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.
价 格:¥电议型 号:T1617产 地:中国大陆
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T16156MT 63-78;化合物MT 63-78MT 63-78
MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM). MT 63-78 blocks prostate cancer growth by inhibiting the lipogenesis and mTORC1 pathways. MT 63-78 has antitumor effects. MT 63–78 also causes cell mitotic arrest and apoptosis.
价 格:¥电议型 号:T16156产 地:中国大陆
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T16153MS4078;化合物MS4078MS4078
MS4078 is an inhibitor and aplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, with a Kd of 19?nM for binding affinity to ALK.
价 格:¥电议型 号:T16153产 地:中国大陆