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T17836DMAC-SPP；化合物 T17836DMAC-SPP
DMAC-SPP is a cleavable linker vital in ADC synthesis. DMAC-SPP joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
价 格：￥电议型 号：T17836产 地：中国大陆
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T17835DMAC-PDB；化合物 T17835DMAC-PDB
DMAC-PDB is a cleavable linker vital in ADC synthesis. DMAC-PDB joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
价 格：￥电议型 号：T17835产 地：中国大陆
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T17834DM4-SPDP；化合物 T17834DM4-SPDP
DM4-SPDP, a drug-linker conjugate, integrates the antitubulin agent DM4 with the linker SMCC, facilitating the creation of antibody drug conjugates[1]. Additionally, SPDP serves as a short-chain crosslinker enabling amine-to-sulfhydryl conjugation, leveraging NHS-ester and pyridyldithiol groups to establish cleavable (reducible) disulfide bonds with cysteine sulfhydryls[2][3].
价 格：￥电议型 号：T17834产 地：中国大陆
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T17833DM4-SMCC；化合物 T17833DM4-SMCC
DM4-SMCC, a non-cleavable drug-linker conjugate for antibody-drug conjugates (ADC), leverages the antitumor efficacy of DM4 (an antitubulin agent) through attachment with the SMCC linker, exhibiting antitumor activity[1].
价 格：￥电议型 号：T17833产 地：中国大陆
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T17832DM1-PEG4-DBCO；化合物 T17832DM1-PEG4-DBCO
DM1-(PEG)4-DBCO is a drug-linker conjugate that combines the potent microtubulin inhibitor mertansine (DM1) with the DBCO-PEG4-Ahx linker for the development of antibody-drug conjugates (ADCs). This conjugation aims to mitigate the systemic toxicity associated with maytansine while improving tumor-specific delivery, leveraging DM1’s capabilities as an antibody-conjugatable maytansinoid.
价 格：￥电议型 号：T17832产 地：中国大陆
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T17831Dioxoisoindolin-O-PEG-OMe (MW 2000)；化合物 T17831(1,3-dioxoisoindolin-2-yl)-O-PEG-OMe (MW 2000)；(1,3-di
Dioxoisoindolin-O-PEG-OMe (MW 2000) is a polyethylene glycol (PEG) based PROTAC linker, which finds application in the synthesis of PROTACs[1].
价 格：￥电议型 号：T17831产 地：中国大陆
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T17830Dioxoisoindolin-O-PEG-OH (MW 2000)；化合物 T17830(1,3-dioxoisoindolin-2-yl)-O-PEG-OH (MW 2000)；(1,3-diox
Dioxoisoindolin-O-PEG-OH (MW 2000) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of PROTACs (proteolysis targeting chimeras)[1].
价 格：￥电议型 号：T17830产 地：中国大陆
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T1783LXR-623；化合物LXR623LXR623|||WAY 252623；LXR623|||WAY 252623
LXR-623 (WAY 252623) is an orally bioavailable and highly specifical synthetic modulator of LXR.
价 格：￥电议型 号：T1783产 地：中国大陆
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T1782LCanagliflozin hemihydrate；卡格列净半水合物JNJ28431754|||TA 7284|||TA7284|||TA-7284|||JNJ 28431754|||JNJ-2843
Canagliflozin hemihydrate (TA 7284) is a drug of the gliflozin class or subtype 2 sodium-glucose transport inhibitors used for the treatment of type 2 diabetes. SGLT2 is responsible for at least 90% of renal glucose reabsorption (SGLT1 being responsible for the remaining 10%). Blocking this transporter causes up to 119 grams of blood glucose per day to be eliminated through the urine, corresponding to 476 kilocalories.
价 格：￥电议型 号：T1782L产 地：中国大陆
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T17829Diketone-PEG4-PFP ester；化合物 T17829Diketone-PEG4-PFP ester
Diketone-PEG4-PFP ester is a polyethylene glycol (PEG) derivative employed as a PROTAC linker in the fabrication of proteolysis-targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T17829产 地：中国大陆
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T17828Diketone-PEG4-Biotin；化合物 T17828Diketone-PEG4-Biotin
Diketone-PEG4-Biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17828产 地：中国大陆
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T17827Diketone-PEG12-DBCO；化合物 T17827Diketone-PEG12-DBCO
Diketone-PEG12-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17827产 地：中国大陆
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T17826Diketone-PEG12-Biotin；化合物 T17826Diketone-PEG12-Biotin
Diketone-PEG12-Biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17826产 地：中国大陆
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T17825Diketone-PEG11-PFP ester；化合物 T17825Diketone-PEG11-PFP ester
Diketone-PEG11-PFP ester serves as a PEG-based PROTAC linker for PROTAC synthesis[1].
价 格：￥电议型 号：T17825产 地：中国大陆
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T17824Diketone-PEG11-Diketone；化合物 T17824Diketone-PEG11-Diketone
Diketone-PEG11-Diketone is a polyethylene glycol (PEG)-based linker utilized for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T17824产 地：中国大陆
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T17823Diethylene glycol bis(p-toluenesulfonate)二乙二醇双对甲苯磺酸酯二乙二醇双对甲苯磺酸酯|||Bis-Tos-PEG2|||Diethylene glycol d
Diethylene glycol bis(p-toluenesulfonate) (Bis-Tos-PEG2) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格：￥电议型 号：T17823产 地：中国大陆
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T17822Diazo Biotin-PEG3-DBCO；化合物 T17822Diazo Biotin-PEG3-DBCO
Diazo Biotin-PEG3-DBCO is a cleavable three-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T17822产 地：中国大陆
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T17820Dde Biotin-PEG4-TAMRA-PEG4 Alkyne；化合物 T17820Dde Biotin-PEG4-TAMRA-PEG4 Alkyne
Dde Biotin-PEG4-TAMRA-PEG4 Alkyne, a PEG-based PROTAC linker, facilitates PROTAC synthesis[1].
价 格：￥电议型 号：T17820产 地：中国大陆
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T1782Canagliflozin；卡格列净JNJ 24831754ZAE|||JNJ 28431754AAA|||TA 7284|||JNJ 28431754；卡格列净|||JNJ 24831754ZAE|
Canagliflozin (JNJ 28431754AAA), a sodium-glucose transporter 2( SGLT2) and P-Glycoprotein inhibitor, is used in type 2 diabetes.
价 格：￥电议型 号：T1782产 地：中国大陆
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T17819Thalidomide-O-amido-C8-NH2；化合物 T17819E3 Ligase Ligand-Linker Conjugates 20|||Cereblon Ligand-Linker
Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2) is a synthesized E3 ligase ligand-linker conjugate comprising a Thalidomide-based cereblon ligand and a linker. This compound is useful in the synthesis of PROTACs, as per reference [1].
价 格：￥电议型 号：T17819产 地：中国大陆
