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T15019CUR61414;化合物CUR61414CUR61414
CUR61414 is a cell-permeable inhibitor of Hedgehog signaling pathway (IC50?=100-200 nM) and selectively binds to smoothened (Ki = 44 nM).
价 格:¥电议型 号:T15019产 地:中国大陆
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T14199ALZ-801;化合物ALZ-801Valiltramiprosate;Valiltramiprosate
ALZ-801 is an orally available, valine-conjugated prodrug of tramiprosate. ALZ-801 is an advanced and markedly improved candidate for the treatment of Alzheimer´s disease. ALZ-801 is a potent and orally available small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor, a valine-conjugated prodrug of Tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound.
价 格:¥电议型 号:T14199产 地:中国大陆
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T14198ALX-1393;化合物ALX-1393ALX-1393
ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits the activity of spontaneous networks by inducing glycinergic tetanic currents in the abdominal horn of the spinal cord. Antiinjurious effects on thermal, mechanical and chemical stimuli in rat models of acute pain.
价 格:¥电议型 号:T14198产 地:中国大陆
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T14197LAlvameline maleate;化合物 T14197LLu 25-109-M;Lu 25-109-M
Alvameline maleate is used as a Partial M1 Agonist and M2/M3 Antagonist.
价 格:¥电议型 号:T14197L产 地:中国大陆
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T14196Alternariol;交链孢酚Alternariol
Alternariol (AOH), a mycotoxin synthesized by Alternaria species, displays numerous therapeutic and biological effects, including phytotoxic, cytotoxic, anti-HIV, anti-cancer, and anti-microbial properties. It functions by inhibiting the catalytic activity of topoisomerase I and II enzymes.
价 格:¥电议型 号:T14196产 地:中国大陆
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T14195ALS-8112;化合物 T14195ALS-8112
ALS-8112 is a inhibitor of respiratory syncytial virus (RSV) polymerase. The 5´-triphosphate form of ALS-8112 inhibits RSV polymerase (IC50: 0.02 μM).
价 格:¥电议型 号:T14195产 地:中国大陆
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T14194β-NETA;化合物β-NETAα-NETA;α-NETA
β-NETA (α-NETA) is a stable, noncompetitive, slowly reversible choline acetyltransferase (ChAT) inhibitor with an IC50 of 9 μM and is a potent chemokine-like receptor-1 (CMKLR1) antagonist. β-NETA has anti-cancer activity[1][2]. β-NETA weakly inhibits cholinesterase (IC50=84 ?M) and acetylcholinesterase (IC50=300 ?M).
价 格:¥电议型 号:T14194产 地:中国大陆
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T14193α-Galactosylceramide;化合物KRN7000KRN7000|||α-GalCer;KRN7000|||α-GalCer
α-Galactosylceramide (KRN7000) is a synthetic glycolipid with antitumorial and immunostimulatory and is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide and CD1d can bind to the T cell antigen receptor of NKT cells.
价 格:¥电议型 号:T14193产 地:中国大陆
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T14192α-Amyrin acetate;化合物α-?Amyrin acetateα-?Amyrin acetate;Α-香树精乙酯|||α-?Amyrin acetate
α-Amyrin acetate is a natural product( triterpeno), with anti-inflammatory activity, antispasmodic profile and the relaxant effect.
价 格:¥电议型 号:T14192产 地:中国大陆
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T14191Alpelisib hydrochloride;化合物 T14191BYL-719 hydrochloride;BYL-719 hydrochloride
Alpelisib hydrochloride (BYL-719 hydrochloride) exhibits anticancer properties[1][2]. As a potent, selective PI3Kα inhibitor with high oral bioavailability, it demonstrates IC50 values of 5 nM for p110α, 250 nM for p110γ, 290 nM for p110δ, and 1200 nM for p110β, indicating its efficacy in targeting specific enzymes involved in cancer cell proliferation.
价 格:¥电议型 号:T14191产 地:中国大陆
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T14190Alniditan;化合物 T14190Alnitidan;Alnitidan
Alniditan is a receptors agonist of 5-HT1B/1D in HEK 293 cells (IC50: 1.7 and 1.3 nM). For 5-HT1B/1D receptors, the pKi values are 8.96 and 9.40, respectively.
价 格:¥电议型 号:T14190产 地:中国大陆
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T1419Azithromycin hydrate;阿奇霉素二水合物CP-62993 dihydrate|||Azithromycin dihydrate;CP-62993 dihydrate|||阿奇霉素二水
Azithromycin hydrate (CP-62993 dihydrate) is a semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis.
价 格:¥电议型 号:T1419产 地:中国大陆
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T14189Almokalant;化合物 T14189H 234?/09;H 234?/09
Almokalant is a class III antiarrhythmic drug, acts as a potassium channel blocker. And it inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current.
价 格:¥电议型 号:T14189产 地:中国大陆
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T14188ALLO-2;化合物ALLO-2ALLO-2
ALLO-2 is a Inhibitor of Drug-Resistant Smo Mutant.It inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.
价 格:¥电议型 号:T14188产 地:中国大陆
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T1418617-ODYA;17-十八炔酸Alkynyl Stearic Acid;17-十八炔酸|||Alkynyl Stearic Acid
17-ODYA (Alkynyl Stearic Acid) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T14186产 地:中国大陆
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T14185Alkynyl Palmitic Acid;15-十六碳炔酸Alkynyl Palmitic Acid
Alkynyl Palmitic Acid is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T14185产 地:中国大陆
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T14184Alkynyl myristic acid;化合物Alkynyl myristic acidtetradec-13-ynoic acid|||13-Tetradecyn-1-oic acid|||13
Alkynyl myristic acid (13-Tetradecyn-1-oic acid) is an alkyl chain-based PROTAC linker.
价 格:¥电议型 号:T14184产 地:中国大陆
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T14183Alkyne-PEG4-maleimide;化合物 T14183Alkyne-PEG4-maleimide
Alkyne-PEG4-maleimide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14183产 地:中国大陆
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T14182Alkyne-ethyl-PEG1-Boc;化合物 T14182Alkyne-ethyl-PEG1-t-butyl ester;Alkyne-ethyl-PEG1-t-butyl ester
Alkyne-ethyl-PEG1-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14182产 地:中国大陆
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T14181Alizarin Red S sodium;茜素红钠盐ARS sodium;ARS sodium|||茜素红钠盐
Alizarin Red S sodium (ARS sodium) (ARS sodium) is an anthraquinone dye. Which has been widely used to evaluate calcium deposits in cell culture[1].
价 格:¥电议型 号:T14181产 地:中国大陆