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T14141AGI-24512化合物AGI-24512MAT2A|||S-adenosylmethionine Synthetase|||HCT116
AGI-24512 is a inhibitor of methionine adenosyltransferase 2A (MATA2 ).It is useful for treatment of cancer and blocks growth of MTAP-deleted cancer cells in vitro.
价 格:¥电议型 号:T14141产 地:中国大陆
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T14140Agaric acid;落叶松蕈酸Agaricinic Acid;落叶松蕈酸|||Agaricinic Acid
Agaricic acid is an adenine nucleotide translocase antagonist.It is obtained from various plants of the fungous tribe, i.e. Polyporus officinalis and Polyporus igniarius. Agaric acid (Agaricinic Acid) induces mitochondrial permeability transition through its interaction with the adenine nucleotide translocase. Agaric acid promotes efflux of accumulated Ca 2+, collapse of transmembrane potential, and mitochondrial swelling. Agaric acid is used to regulate lipid metabolism.
价 格:¥电议型 号:T14140产 地:中国大陆
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T1414Sodium 2-mercaptoethanesulfonate;美司钠Mitexan|||Uromitexan|||Mesna|||Mesnum|||Mesnex;Mitexan|||美司那|||美
Sodium 2-mercaptoethanesulfonate (Uromitexan) is a sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from antineoplastic agents, such as ifosfamide or cyclophosphamide.
价 格:¥电议型 号:T1414产 地:中国大陆
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T14139Aganepag;化合物 T14139AGN 210937;AGN 210937
Aganepag, a potent Prostanoid EP2 receptor agonist, exhibits remarkable selectivity with an EC50 of 0.19 nM, demonstrating no activity at the EP4 receptor. Its applications are primarily in the fields of wound healing, scar reduction, scar prevention, and the treatment and prevention of wrinkles.
价 格:¥电议型 号:T14139产 地:中国大陆
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T14138AG-825;化合物AG-825Tyrphostin AG-825;Tyrphostin AG-825
AG-825(Tyrphostin C15) is a selective and competitive ErbB2 inhibitor that inhibits tyrosine phosphorylation with an IC50 value of 0.35 μM.AG-825 (Tyrphostin C15) inhibits HER2 and shows anticancer activity in a mouse xenograft model of breast cancer.AG-825 ( Tyrphostin C15) is a potentially active molecule for overcoming manganese-induced neurotoxicity or the development of Alzheimer´s disease, and promotes apoptosis in human neutrophils, which could be used in the study of breast cancer.
价 格:¥电议型 号:T14138产 地:中国大陆
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T14137AG 1295;酪氨酸磷酸化抑制剂AG1295AG 1295
AG 1295, a selective inhibitor of platelet-derived growth factor receptor (PDGFR) tyrosine-kinase, effectively halts PDGFR autophosphorylation without impacting the autophosphorylation of the EGF receptor[1][2][3][4].
价 格:¥电议型 号:T14137产 地:中国大陆
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T14136AG-024322;化合物 T14136AG-024322
AG-024322 is a potent ATP-competitive inhibitor of pan-CDK against cell cycle kinases CDK1, CDK2, and CDK4(Ki values in the 1-3 nM range)
价 格:¥电议型 号:T14136产 地:中国大陆
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T14134Afabicin;化合物 T14134AFN-1720|||Debio 1450;AFN-1720|||Debio 1450
Afabicin is the prodrug of Debio1452. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci.
价 格:¥电议型 号:T14134产 地:中国大陆
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T14133AEOL-10150 pentachloride;化合物AEOL-10150 pentachlorideAEOL-10150 pentachloride
AEOL-10150 pentachloride is a metalloporphyrin catalytic antioxidant. AEOL-10150 pentachloride also is a superoxide dismutase mimetic. Which protects lungs from radiation-induced injury.
价 格:¥电议型 号:T14133产 地:中国大陆
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T14132Aeide-C1-NHS ester;化合物 T14132Aeide-C1-NHS ester
Aeide-C1-NHS ester, an alkyl/ether-based PROTAC linker, finds utility in the synthesis of PROTACs[1].
价 格:¥电议型 号:T14132产 地:中国大陆
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T14131ADPS;化合物ADPSN-Ethyl-N-(3-sulfopropyl)-3-methoxyaniline sodium salt|||ESPAS;N-Ethyl-N-(3-sulfopropyl)
ADPS (N-Ethyl-N-(3-sulfopropyl)-3-methoxyaniline sodium salt) is a kind of new Trinder´s reagents, which are high water-soluble aniline derivatives. It is widely used in diagnostic and biochemical tests.
价 格:¥电议型 号:T14131产 地:中国大陆
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T14130Adomeglivant;阿度格列凡LY2409021;LY2409021
Adomeglivant (LY2409021) is a potent and selective glucagon receptor antagonist. Which is used in clinical trial for type 2 diabetes mellitus.
价 格:¥电议型 号:T14130产 地:中国大陆
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T14129Adenylosuccinic acid;化合物 T14129Aspartyl adenylate|||Adenylosuccinate;Aspartyl adenylate|||Adenylosuc
Adenylosuccinic acid (Adenylosuccinate; Aspartyl adenylate) is a purine ribonucleoside monophosphate and plays a role in nucleotide cycle metabolite. Adenylosuccinic acid has the potential for the study of duchenne muscular dystrophy(DMD)[1] and can be converted into fumaric acid through adenylosuccinate lyase.
价 格:¥电议型 号:T14129产 地:中国大陆
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T14127Adenosine A1 receptor activator T62;化合物Adenosine A1 receptor activator T62Adenosine A1 receptor acti
Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve-injury pain[1][2][3].
价 格:¥电议型 号:T14127产 地:中国大陆
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T14126ADDA 5 hydrochloride;化合物 T14126ADDA 5 hydrochloride
ADDA 5 hydrochloride is a partial non-competitive inhibitor of cytochrome c oxidase (CcO). For purified CcO from human glioma and bovine heart, the IC50s are 18.93 μM and 31.82 μM , respectively.
价 格:¥电议型 号:T14126产 地:中国大陆
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T14125Adarotene;化合物AdaroteneST1926;ST1926
Adarotene (ST1926) is an effective apoptosis inducer. It surprisingly produces DNA damage and exhibits a potent antiproliferative activity on a large panel of human tumor cells.
价 格:¥电议型 号:T14125产 地:中国大陆
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T14124ADAMTS-5 Inhibitor;化合物ADAMTS-5 InhibitorADAMTS-5 Inhibitor
ADAMTS-5 Inhibitor is an inhibitor of ADAMTS-5 with an IC50 of 1.1 ?M and can be used in studies about cartilage destruction in arthritis.
价 格:¥电议型 号:T14124产 地:中国大陆
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T14123ACT 178882;化合物 T14123ACT 178882
ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM).
价 格:¥电议型 号:T14123产 地:中国大陆
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T14122Active-mono-sulfone-PEG8-acid;化合物 T14122Active-mono-sulfone-PEG8-acid
Active-mono-sulfone-PEG8-acid is a polyethylene glycol (PEG) derivative serving as a linker for PROTAC synthesis[1].
价 格:¥电议型 号:T14122产 地:中国大陆
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T14121Actinonin化合物 T14121(-)-Actinonin
Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces and a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM, it also is an apoptosis inducer. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase, it also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin has antiproliferative and antitumor activities[1][2][3][4][5].
价 格:¥电议型 号:T14121产 地:中国大陆