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T11975PROTAC Mcl1 degrader-1PROTAC Mcl1 degrader-1
PROTAC Mcl1 degrader-1 induces the ubiquitination and proteasomal degradation of Mcl-1 by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1 inhibitor S1-6 with μM-range affinity.?PROTAC Mcl1 degrader-1, a proteolysis targeting
价 格:¥电议型 号:T11975产 地:美洲
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T12038Migalastat hydrochlorideMigalastat hydrochloride,GR181413A,
Migalastat hydrochloride is a potent and competitive α-galactosidase A (α-Gal A) inhibitor (human α-Gal A,IC50 of 0.04 μM ).
价 格:¥电议型 号:T12038产 地:美洲
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T12089Mogroside I A1Mogroside I A1
Mogroside I A1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, exhibiting antioxidant, antidiabetic and anticancer activities.
价 格:¥电议型 号:T12089产 地:美洲
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T12090Mogroside I E1Mogroside I E1
Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener.
价 格:¥电议型 号:T12090产 地:美洲
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T12191NBTGRNBTGR
NBTGR is a potent nucleoside transport inhibitor(adenosine uptake ,Ki of 70 nM).
价 格:¥电议型 号:T12191产 地:美洲
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T12556PROTAC B-Raf degrader 1PROTAC B-Raf degrader 1
PROTAC B-Raf degrader 1 is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf,PROTAC B-Raf degrader 1 With anti-cancer activity.
价 格:¥电议型 号:T12556产 地:美洲
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T12559PROTAC BET degrader-2PROTAC BET degrader-2
PROTAC BET degrader-2 is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins (IC50 of 9.6 nM ).
价 格:¥电议型 号:T12559产 地:美洲
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T12560PROTAC BRD9 Degrader-1PROTAC BRD9 Degrader-1
PROTAC BRD9 Degrader-1 is a lead PROTAC BRD9 chemical degrader with IC50 of 13.5 nM.
价 格:¥电议型 号:T12560产 地:美洲
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T12770RR-11a analogRR-11a analog
RR-11a analog is a potent and selective asparaginyl endopeptidases (AE) (Legumain) inhibitors(IC50 values of 4.5 nM, 4.5 nM and 31 nM for AE1 in Trichomonas Vaginalis, AE in Ixodes ricinus and AE in Schistosoma mansoni, respectively).
价 格:¥电议型 号:T12770产 地:美洲
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T12970SolabegronSolabegron,GW 427353,
Solabegron is a selective agonist of β3-adrenergic receptor, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR(EC50 : 22 nM). It is used for treatment of overactive bladder and irritable bowel syndrome.
价 格:¥电议型 号:T12970产 地:美洲
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T13140Umbralisib R-enantiomerUmbralisib R-enantiomer,TGR-1202 R-enantiomer,RP5264 R-enantiomer
Umbralisib R-enantiomer (TGR-1202 R-enantiomer) is an inhibitor of PI3Kδ, which is the less active enantiomer of TGR-1202.
价 格:¥电议型 号:T13140产 地:美洲
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T13329VofopitantVofopitant,GR 205171,
Vofopitant is potent antagonist of tachykinin NK1 receptor(pKis of 10.6, 9.5, and 9.8 for human, rat and ferret NK1 receptor, respectively).
价 格:¥电议型 号:T13329产 地:美洲
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T13473αvβ1 integrin-IN-1αvβ1 integrin-IN-1
αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin(IC50 of 0.63 nM), with antifibrotic effects.
价 格:¥电议型 号:T13473产 地:美洲
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T13631c(phg-isoDGR-(NMe)k)c(phg-isoDGR-(NMe)k)
c (phg-isoDGR- (NMe) k) is a selective and effective α5β1-integrin ligand with IC50 of 2.9 nM.
价 格:¥电议型 号:T13631产 地:美洲
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T13721Homo-PROTAC cereblon degrader 1Homo-PROTAC cereblon degrader 1
Homo-PROTAC cereblon degrader 1 ?is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.
价 格:¥电议型 号:T13721产 地:美洲
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T13722Homo-PROTAC pVHL30 degrader 1Homo-PROTAC pVHL30 degrader 1
Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC.
价 格:¥电议型 号:T13722产 地:美洲
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T13776Mogroside II-?AMogroside II-?A
Mogroside II-?A is isolated from Siraitia grosvenorii.
价 格:¥电议型 号:T13776产 地:美洲
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T13840PROTAC FAK degrader 1PROTAC FAK degrader 1
PROTAC FAK degrader 1 is a selective and potent degrader of focal adhesion kinase (Fak) (IC50 of 6.5 nM).
价 格:¥电议型 号:T13840产 地:美洲
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T13844PROTAC K-Ras Degrader-1PROTAC K-Ras Degrader-1
PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC.
价 格:¥电议型 号:T13844产 地:美洲
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T13847PROTAC SGK3 degrader-1PROTAC SGK3 degrader-1,SGK3-PROTAC1,
PROTAC SGK3 degrader-1, is a potent SKG3 degrader based on PROTAC.
价 格:¥电议型 号:T13847产 地:美洲