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T2562EltrombopagEltrombopag,SB-497115-GR,SB-497115
Eltrombopag, an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet thrombopoietin receptor (TPO-R or CD110).
价 格:¥电议型 号:T2562产 地:美洲
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T4547GrazoprevirGrazoprevir,MK-5172,
MK-5172 is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0.08 nM (gt2a), 0.90 nM (gt3a), 0.01 nM (gt1b), 0.15 nM (gt2b), respectively.
价 格:¥电议型 号:T4547产 地:美洲
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T4635RalinepagRalinepag,APD811,
Ralinepag is a potent, orally bioavailable and non-prostanoid prostacyclin (IP) receptor agonist, with EC50s of 8.5 nM, 530 nM and 850 nM for human and rat IP receptor and human DP1 receptor, respectively.
价 格:¥电议型 号:T4635产 地:美洲
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T4978Sarpogrelate hydrochlorideSarpogrelate hydrochloride,MCI-9042,
Sarpogrelate(MCI-9042) hydrochloride, a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD. Target: 5-HT2 Recepter Sarpogrelate is a drug which acts as an antagonist at the 5HT2A and 5-HT2B receptors. Sarpo
价 格:¥电议型 号:T4978产 地:美洲
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T4S1173Agrimol BAgrimol B
1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.
价 格:¥电议型 号:T4S1173产 地:美洲
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T5167CebranopadolCebranopadol,GRT6005,
Cebranopadol is an analgesic NOP and opioid receptor agonist with Kis of 0.9 nM, 0.7 nM, 2.6 nM, 18 nM for human NOP, μ-opioid (MOP), κ-opioid (KOP) and δ-opioid (DOP) receptor, respectively.
价 格:¥电议型 号:T5167产 地:美洲
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T5806Growth hormone releasing peptideGrowth hormone releasing peptide
Growth hormone releasing peptide ia a natual product ,and has anti-inflammatory effects, due to its inhibitory effect on PKC-induced activation of p38, JNK and NF-κB, possibly by targeting to MKP-1 and PP2A.
价 格:¥电议型 号:T5806产 地:美洲
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T6098CabotegravirCabotegravir,S/GSK1265744,GSK-1265744
Cabotegravir (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM).
价 格:¥电议型 号:T6098产 地:美洲
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T6198DolutegravirDolutegravir,GSK1349572,S/GSK1349572
Dolutegravir (IC50=2.7 nM), a two-metal-binding HIV integrase inhibitor, exhibits medium activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
价 格:¥电议型 号:T6198产 地:美洲
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T6236OzagrelOzagrel,OKY-046,Domenan
Ozagrel is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.
价 格:¥电议型 号:T6236产 地:美洲
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T6300DegrasynDegrasyn,WP1130,
Degrasyn (WP1130), a specific deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor, also inhibits Bcr/Abl, which is a JAK2 transducer (without affecting 20S proteasome) and activator of transcription (STAT).
价 格:¥电议型 号:T6300产 地:美洲
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T6390Anagrelide HClAnagrelide HCl,Anagrelide hydrochloride,BL4162A
Anagrelide Hydrochloride(BL4162A) is a drug used for the treatment of essential thrombocytosis.
价 格:¥电议型 号:T6390产 地:美洲
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T6410BexaroteneBexarotene,LGD1069,Targretin
Bexarotene is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).
价 格:¥电议型 号:T6410产 地:美洲
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T6519GramineGramine,Donaxine,NSC 16892
Gramine, a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for AdipoR2 and AdipoR1, respectively. Gramine is also a human and mouse β2-Adrenergic receptor (β2
价 格:¥电议型 号:T6519产 地:美洲
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T6520Grape Seed ExtractGrape Seed Extract,Grape Seed P.E.,
Grape Seed Extract is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites (BIOFLAVONOIDS and polyphenols) credited with important medicinal properties.
价 格:¥电议型 号:T6520产 地:美洲
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T6615OndansetronOndansetron,SN 307,GR 38032
Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.
价 格:¥电议型 号:T6615产 地:美洲
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T6625Ozagrel hydrochlorideOzagrel hydrochloride,Ozagrel HCl,OKY-046 HCl
Ozagrel HCl is a selective thromboxane A(2) synthetase inhibitor used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.
价 格:¥电议型 号:T6625产 地:美洲
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T8745PROTAC BRAF-V600E degrader-1;化合物2417296-84-3Compound 23;Compound 23
PROTAC BRAF-V600E degrader-1 (Compound 23) selectively induces degradation of BRAF-V600E but not wildtype BRAF.
价 格:¥电议型 号:T8745产 地:中国大陆
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T8744PROTAC BRAF-V600E degrader-2;化合物 T8744PROTAC BRAF-V600E degrader-2
PROTAC BRAF-V600E degrader-2 is a useful organic compound for research related to life sciences. The catalog number is T8744 and the CAS number is 2417296-82-1.
价 格:¥电议型 号:T8744产 地:中国大陆