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T8737GR 125743；化合物GR 125743GR 125743
GR 125743 is a novel antagonist of 5-HT1B/1D receptor.
价 格：￥电议型 号：T8737产 地：中国大陆
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T8701GRP-60367；氯硝柳胺乙醇胺盐GRP-60367
GRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.
价 格：￥电议型 号：T8701产 地：中国大陆
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T8679Epidermal Growth Factor；重组人表皮细胞生长因子Epidermal Growth Factor
Epidermal Growth Factor binds to epidermal growth factor receptor (EGFR) and stimulates cell growth and proliferation. It is approved for the treatment of diabetic foot ulcers.
价 格：￥电议型 号：T8679产 地：中国大陆
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T83947HDAC4 CHDI Degrader 11；化合物 HDAC4 CHDI Degrader 11HDAC4 CHDI Degrader 11
HDAC4 CHDI Degrader 11 is a potent, selective degrader of HDAC4 (PROTAC) with DC_50 values of 4 nM and 6 nM in Jurkat E6-1 and Jurkat cells, respectively. This compound integrates the class IIa HDAC inhibitor trifluoromethyloxadiazole with a ligand for the Von Hippel-Lindau (VHL) protein through a linker. Demonstrating significant efficacy, HDAC4 CHDI Degrader 11 achieves a DC_50 value of 1 nM in a mouse cell model of Huntington´s disease. For enhanced degradation in neuroblastoma cell lin
价 格：￥电议型 号：T83947产 地：中国大陆
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T83852EGFRvIII Peptide TFA；化合物 EGFRvIII Peptide TFAPEGFRvIII (9-mer)|||Epidermal Growth Factor Receptor Va
EGFRvIII peptide, a synthetic peptide mirroring the EGFRvIII fusion junction—a tumor-specific, perpetually active EGFR variant missing amino acids 6-273 of the wild-type—binds to HLA-A*0201-positive T2 cells under MHC class I at 25 ?g/ml. It enables antigen presentation in dendritic cells from human peripheral blood mononuclear cells (PBMCs), thus activating CD8+ cytotoxic T lymphocytes and prompting IFN-γ production. Administered at 15 ?g/animal with the TLR5 agonist flagellin B, EGFRvIII pepti
价 格：￥电议型 号：T83852产 地：中国大陆
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T83726Tat-βsyn-degron TFA；化合物 Tat-βsyn-degron TFATat-βsyn-degron TFA
Tat-βsyn-degron, an α-synuclein knockdown peptide, integrates three domains: the HIV-1 Tat plasma membrane transduction domain, an α-synuclein binding domain (βsyn) representing amino acids 36-45 of β-synuclein, and a proteasomal targeting domain (degron). It effectively binds to recombinant α-synuclein, demonstrating a significant reduction in α-synuclein levels in primary rat cortical neuron cultures.
价 格：￥电议型 号：T83726产 地：中国大陆
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T83716KSL-128114 TFA；化合物 KSL-128114 TFAAc-rRrGrKkRrSHWX1X2DI-OH (X1=tert-Leucine; X2=Cyclohexylglycine)；Ac
KSL-128114, a peptide inhibitor of the membrane regulator syntenin (Ki = 300 nM), notably diminishes the viability of A2058 melanoma and patient-derived glioblastoma multiforme (GBM) cells in a concentration-dependent manner. Furthermore, when administered at 50 ?M, KSL-128114 elevates survival times in a patient-derived xenograft (PDX) mouse model of GBM, where mice were implanted intracranially with patient-derived GBM cells pre-cultured with KSL-128114.
价 格：￥电议型 号：T83716产 地：中国大陆
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T83705BING TFA；化合物 BING TFABlocker of Inter-membrane Stress Responses of Gram-negative Bacteria；Blocker of
BING, a antimicrobial peptide discovered in Japanese medaka fish (O. laptipes), originates from vacuolar protein sorting-associated protein 13D-like (Vps13D). It exhibits efficacy against a range of Gram-negative and Gram-positive bacteria, notably including methicillin-resistant S. aureus (MRSA; MICs = 4-64 ?g/ml). Furthermore, BING enhances the effectiveness of antibiotics such as ampicillin, amoxicillin, and novobiocin against P. aeruginosa, and it prevents resistance development to kanamycin
价 格：￥电议型 号：T83705产 地：中国大陆
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T8369Adagrasib；化合物MRTX849MRTX849；MRTX849
Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib exhibits inhibitory activity against KRAS G12C mutant tumors.
价 格：￥电议型 号：T8369产 地：中国大陆
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T83671CCP-biotin Peptide (non-cyclized)；化合物 CCP-biotin Peptide (non-cyclized)Citrullinated Filaggrin (Q447
CCP-biotin peptide (non-cyclized) is a linear, biotin-labeled derivative of the circular citrullinated peptide (CCP), mirroring the human filaggrin sequence from amino acids 447 to 467 with specific substitutions (Q447H, S449C, G459R, E460G, and S462C) and a citrullination at arginine 455. This formulation is designed for the identification of anti-citrulline autoantibodies that may recognize and interact with the linear configuration of the peptide.
价 格：￥电议型 号：T83671产 地：中国大陆
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T83668Nucleic Acid Dye Green I；化合物 Nucleic Acid Dye Green INucGel Green I Nucleic Acid Gel Stain|||Green I
Nucleic Acid Dye Green I, a cell-impermeable fluorescent dye, is widely utilized for quantifying both dsDNA and ssDNA due to its excitation and emission peaks at 497 nm and 520 nm, respectively. Additionally, it finds applications in gene expression and RT-PCR assays.
价 格：￥电议型 号：T83668产 地：中国大陆
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T83549(D-Ala2)-GRF (1-29) amide (human)；化合物 (D-Ala2)-GRF (1-29) amide (human)(D-Ala2)-GRF (1-29) amide (hu
(D-Ala2)-GRF (1-29) amide (human) is a potent superagonist of Growth Hormone-Releasing Factor (GRF), demonstrating an exceptionally high Growth Hormone (GH)-releasing activity, approximately 50-fold greater than that of GRF (1-29) in both pigs and rats [1].
价 格：￥电议型 号：T83549产 地：中国大陆
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T83491[K15,R16,L27]VIP(1-7)/GRF(8-27)；化合物 [K15,R16,L27]VIP(1-7)/GRF(8-27)[K15,R16,L27]VIP(1-7)/GRF(8-27)
[K15,R16,L27]VIP(1-7)/GRF(8-27), a selective agonist for the VIP 1 receptor, demonstrates binding IC 50 values of 2 nM for the human VIP 1, 1 nM for the rat VIP 1, and 30,000 nM for the rat VIP 2 receptors, respectively [1]. VIP stands for VASOACTIVE Intestinal Polypeptide.
价 格：￥电议型 号：T83491产 地：中国大陆
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T8346111-Oxomogroside IV A；化合物 11-Oxomogroside IV A11-Oxomogroside IV A
11-Oxomogroside IV A (compound 12), a cucurbitane triterpene glycoside extracted from the unripe fruits of Luo Han Guo, exhibits anti-tumor properties and demonstrates cytotoxicity towards SMMC-7721 tumor cells, with an IC50 value of 288 μg/mL [1].
价 格：￥电议型 号：T83461产 地：中国大陆
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T8344117-Hydroxygracillin；化合物 17-Hydroxygracillin17-Hydroxygracillin
17-Hydroxygracillin, a saponin [1], exhibits various biological activities.
价 格：￥电议型 号：T83441产 地：中国大陆
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T83195Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-7)-GRF (8-27)；化合物 Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-
Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP(1-7)-GRF(8-27) is a selective antagonist [1] for the vasoactive intestinal peptide 1 (VIP 1) receptor.
价 格：￥电议型 号：T83195产 地：中国大陆
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T83166Adipokinetic hormone (Gryllus bimaculatus)；化合物 Adipokinetic hormone (Gryllus bimaculatus)Grybi-AKH；G
Adipokinetic hormone Gryllus bimaculatus (Grybi-AKH), an adipokinetic hormone, mobilizes lipids and carbohydrates from the insect fat body, effectively regulating energy homeostasis. It also enhances the locomotor activity of the two-spotted cricket and has potential applications in human medical studies for body weight regulation, weight loss induction, and the alleviation of glycogen storage disorders [1] [2] [3].
价 格：￥电议型 号：T83166产 地：中国大陆
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T83154Agrimoniin；化合物 AgrimoniinAgrimoniin
Agrimoniin, a phenolic compound, is isolated from the fruit of Fragaria vesca [1].
价 格：￥电议型 号：T83154产 地：中国大陆
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T8300Mogroside IV-E；罗汉果甙 IVmogroside Ive；mogroside Ive|||罗汉果甙 IV
Mogroside IV-E is a triterpenoid glycoside isolated from the extracts of Luo Han Guo. Mogrosides exhibit antidiabetic, antioxidant and anticancer activities.
价 格：￥电议型 号：T8300产 地：中国大陆
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T82924Balugrastim；化合物 BalugrastimCG 10639；CG 10639
Balugrastim (CG 10639), a novel long-acting recombinant granulocyte colony-stimulating factor (G-CSF), results from the genetic fusion of recombinant human serum albumin and G-CSF. It has applications in breast cancer research [1].
价 格：￥电议型 号：T82924产 地：中国大陆
