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T82048IRGRILHDGAYSLTLQGLGIH;化合物 IRGRILHDGAYSLTLQGLGIHIRGRILHDGAYSLTLQGLGIH
IRGRILHDGAYSLTLQGLGIH is a multi-epitope class II rat HER2/neu peptide utilized in research for the class II HER2-DC1 vaccine studies [1].
价 格:¥电议型 号:T82048产 地:中国大陆
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T82047IRGRILHDGAYSLTLQGLGIH TFA;化合物 IRGRILHDGAYSLTLQGLGIH TFAIRGRILHDGAYSLTLQGLGIH TFA
IRGRILHDGAYSLTLQGLGIH TFA, a multi-epitope class II rat HER2/neu peptide, is utilized in the study of class II HER2-DC1 vaccines [1].
价 格:¥电议型 号:T82047产 地:中国大陆
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T81912LSP-GR3;化合物 LSP-GR3LSP-GR3
LSP-GR3, a novel splice modulating oligomer (SMO) consisting of chemically-modified RNA oligonucleotides, potently and specifically directs the alternative splicing of GluR to promote GluR3-flip expression across the central nervous system (CNS).
价 格:¥电议型 号:T81912产 地:中国大陆
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T81901LVGRQLEEFL (mouse);化合物 LVGRQLEEFL (mouse)LVGRQLEEFL (mouse)
G* Peptide, also denoted as LVGRQLEEFL (mouse), represents the amino acid sequence 113 to 122 ([113,122] apoJ) found in apolipoprotein J. This compound displays both anti-inflammatory and anti-atherogenic characteristics. When incorporated into an apoJ mimetic, it results in the formation of the HM-10/10 peptide, which functions as a novel chimeric high-density lipoprotein. The HM-10/10 peptide has been shown to confer protection to the retinal pigment epithelium (RPE) and photoreceptors against
价 格:¥电议型 号:T81901产 地:中国大陆
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T81900LVGRQLEEFL (mouse) (TFA);化合物 LVGRQLEEFL (mouse) (TFA)LVGRQLEEFL (mouse) (TFA)
G* peptide, also known as LVGRQLEEFL (mouse) TFA, is a segment corresponding to amino acids 113 to 122 ([113,122] apoJ) of apolipoprotein J. This compound possesses both anti-inflammatory and anti-atherogenic qualities. When combined with an apoJ mimetic, it constitutes the HM-10/10 peptide, a novel chimeric high-density lipoprotein mimetic peptide. The HM-10/10 peptide is notable for safeguarding retinal pigment epithelium (RPE) and photoreceptors from oxidant-induced cell death as referenced i
价 格:¥电议型 号:T81900产 地:中国大陆
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T81708Nagrestipen;化合物 NagrestipenNagrestipen
Nagrestipen, a variant of the human macrophage inflammatory protein-1 alpha (MIP-1α), also referred to as ECI 301, exhibits antitumor activity. It is employed in therapeutic trials focused on cancer, assessing its efficacy in the contexts of tumors, metastasis, radiation oncology, and the analysis of tumor metastasis [1].
价 格:¥电议型 号:T81708产 地:中国大陆
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T81600Oregon-BAPTA Green 1AM;化合物 Oregon-BAPTA Green 1AMOregon Green 488 BAPTA 1AM;Oregon Green 488 BAPTA 1
Oregon-BAPTA Green 1AM (Oregon Green 488 BAPTA 1AM) is a fluorescent calcium (Ca 2+) indicator, comprising a green fluorescent probe, OG 488, and a cell-permeable calcium chelator, BAPTA AM.
价 格:¥电议型 号:T81600产 地:中国大陆
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T81386PROTAC BRD4 Degrader-22;化合物 PROTAC BRD4 Degrader-22PROTAC BRD4 Degrader-22
PROTAC BRD4 Degrader-22 (Compd 44h) is a PROTAC-based degrader targeting BRD4, exhibiting a pDC50 of 9.2 in MOLT4 cells over 24 hours [1].
价 格:¥电议型 号:T81386产 地:中国大陆
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T81385PROTAC BRD9 Degrader-2;化合物 PROTAC BRD9 Degrader-2PROTAC BRD9 Degrader-2
PROTAC BRD9 Degrader-2 is a bifunctional compound designed for the targeted degradation of BRD9 in cancer research applications.
价 格:¥电议型 号:T81385产 地:中国大陆
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T81384PROTAC BRD9 Degrader-3;化合物 PROTAC BRD9 Degrader-3PROTAC BRD9 Degrader-3
PROTAC BRD9 Degrader-3 is a bifunctional degrader targeting BRD9, utilized in cancer research.
价 格:¥电议型 号:T81384产 地:中国大陆
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T81383PROTAC BRD9 Degrader-5;化合物 PROTAC BRD9 Degrader-5PROTAC BRD9 Degrader-5
PROTAC BRD9 Degrader-5 is a proteolysis targeting chimera (PROTAC) designed for the specific degradation of Bromodomain-containing protein 9 (BRD9).
价 格:¥电议型 号:T81383产 地:中国大陆
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T81382PROTAC BRD9 Degrader-7;化合物 PROTAC BRD9 Degrader-7PROTAC BRD9 Degrader-7
PROTAC BRD9 Degrader-7 is a selective and orally active BRD9 degrader with a DC50 of 1.02 nM and demonstrates superior pharmacokinetics, evidenced by a Cmax of 3436.95 ng/mL [1].
价 格:¥电议型 号:T81382产 地:中国大陆
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T81381PROTAC eDHFR Degrader-1;化合物 PROTAC eDHFR Degrader-1PROTAC eDHFR Degrader-1
PROTAC eDHFR Degrader-1 is a potent degrader targeting eDHFR-YFP and various proteins of interest (POIs), such as YFP and Luciferase [1].
价 格:¥电议型 号:T81381产 地:中国大陆
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T81380PROTAC EGFR degrader 7 diTFA;化合物 PROTAC EGFR degrader 7 diTFAPROTAC EGFR degrader 7 diTFA
PROTAC EGFR degrader 7 (compound 13b) is a potent, selective, CRBN-recruiting EGFRL858R/T790M degrader with a DC50 of 13.2 nM. It effectively inhibits proliferation of NCI-H1975 cells with an IC50 of 46.82 nM, induces apoptosis, and causes a G2/M phase arrest in these cells. Demonstrating antitumor activity, this compound is applicable in non-small cell lung cancer (NSCLC) research.
价 格:¥电议型 号:T81380产 地:中国大陆
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T81379PROTAC GDI2 Degrader-1;化合物 PROTAC GDI2 Degrader-1PROTAC GDI2 Degrader-1
PROTAC GDI2 Degrader-1 (Compound 21) is a potent degrader of PROTAC GDI2, demonstrating outstanding antitumor activity in vivo within pancreatic xenograft models that overexpress GDI2 [1].
价 格:¥电议型 号:T81379产 地:中国大陆
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T81377PROTAC NSD3 degrader-1;化合物 PROTAC NSD3 degrader-1PROTAC NSD3 degrader-1
PROTAC NSD3 degrader-1 (compound 56) is a targeted degradation agent for the Nuclear receptor binding SET domain protein NSD3. It effectively induces the degradation of NSD3 in NCI-H1703 and A549 lung cancer cell lines, with DC50 values of 1.43 and 0.94 μM, respectively. Additionally, it hinders H3K36 methylation, triggers apoptosis, and arrests the cell cycle. Furthermore, PROTAC NSD3 degrader-1 diminishes the expression of NSD3-related genes, including CDC25A, ALDH1A1, and IGFBP.
价 格:¥电议型 号:T81377产 地:中国大陆
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T81376PROTAC SMARCA2 degrader-2;化合物 PROTAC SMARCA2 degrader-2PROTAC SMARCA2 degrader-2
PROTAC SMARCA2 degrader-2, a selective and powerful degrader of SMARCA2/4, exhibits an IC50 of <0.1 μΜ in the HeLa HiBiT assay.this compound holds promise for research into cancers related to or deficient in SMARCA4 [1].
价 格:¥电议型 号:T81376产 地:中国大陆
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T81375PROTAC TTK degrader-1;化合物 PROTAC TTK degrader-1PROTAC TTK degrader-1
PROTAC TTK degrader-1, a potent threonine tyrosine kinase (TTK) PROTAC degrader, demonstrates DC50 values of 1.7 nM in COLO-205 cells and 5.8 nM in HCT-116 cells, indicating effective target degradation. Furthermore, it shows anticancer efficacy in a xenograft mouse model with COLO-205 human colorectal cancer cells [1].
价 格:¥电议型 号:T81375产 地:中国大陆
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T81374PROTAC TTK degrader-2;化合物 PROTAC TTK degrader-2PROTAC TTK degrader-2
PROTAC TTK Degrader-2 is a potent threonine tyrosine kinase (TTK) PROTAC degrader, achieving DC50 values of 3.1 nM in COLO-205 cells and 12.4 nM in HCT-116 cells. It demonstrates effective target degradation and anticancer activity in a COLO-205 human colorectal cancer cell xenograft mouse model [1].
价 格:¥电议型 号:T81374产 地:中国大陆
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T81370Protegrin-1;化合物 Protegrin-1PG1;PG1
Protegrin-1, an antimicrobial peptide, exhibits antimicrobial activity [1].
价 格:¥电议型 号:T81370产 地:中国大陆