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T78647PROTAC BRD4 Degrader-16;化合物 PROTAC BRD4 Degrader-16PROTAC BRD4 Degrader-16
PROTAC BRD4 Degrader-16 is a potent degrader of BRD4, exhibiting IC50 values of 34.58 nM for BRD4 (BD1) and 40.23 nM for BRD4 (BD2). It significantly reduces Cyclin B1 expression, thereby impeding G2/M phase progression, and induces apoptosis in MV-4-11 cells [1].
价 格:¥电议型 号:T78647产 地:中国大陆
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T78629PROTAC α-synuclein degrader 3;化合物 PROTAC α-synuclein degrader 3PROTAC α-synuclein degrader 3
PROTAC α-synuclein degrader 3 (compound 5) serves as a potent and selective agent for degrading α-synuclein and is utilized in Parkinson´s disease research [1].
价 格:¥电议型 号:T78629产 地:中国大陆
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T78540α-CGRP (mouse, rat) TFA;化合物 α-CGRP (mouse, rat) TFAα-CGRP (mouse, rat) TFA
α-CGRP (mouse, rat) TFA, a neuropeptide belonging to the calcitonin gene-related peptide (CGRP) family, is predominantly located at neuromuscular junctions and functions as a potent vasodilator. Peripheral administration of α-CGRP (mouse, rat) TFA may result in decreased blood pressure and elevated heart rate, in addition to the relaxation of colonic smooth muscle. This compound shows promising utility in the investigation of cardiovascular, pro-inflammatory, migraine, and metabolic conditions [
价 格:¥电议型 号:T78540产 地:中国大陆
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T78445Bromocresol green;溴甲酚绿Bromocresol green
Bromocresol Green, a triphenylmethane dye, serves primarily as a pH indicator transitioning from yellow (λmax=435 nm, protonated form) at pH 4.15 to blue (λmax=615 nm, deprotonated form) in alkaline environments. Utilized in biochemical analysis, it quantifies serum protein and albumin, assesses creatinine concentration, and evaluates cell viability [1] [2] [3] [4]. The dye exhibits a bio-based, yellow-green to blue-green hue.
价 格:¥电议型 号:T78445产 地:中国大陆
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T78328Efbemalenograstim alfa;化合物 Efbemalenograstim alfaF 627|||Bineuta|||Benegrastim;F 627|||Bineuta|||Ben
Efbemalenograstim alfa (F 627) is a recombinant fusion protein comprising a long-acting dimeric granulocyte colony-stimulating factor (G-CSF) with two human G-CSF molecules connected via a peptide linker to a human immunoglobulin G2 (hIgG2)-Fc fragment. This biopharmaceutical agent induces the production of white blood cells [1].
价 格:¥电议型 号:T78328产 地:中国大陆
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T78173Aβ/tau aggregation-IN-3;化合物 Aβ/tau aggregation-IN-3Aβ/tau aggregation-IN-3
Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 ?M in an Aβ-Thioflavin T (Aβ-ThT) functional aggregation assay. This compound demonstrates anti-amyloid activity [1].
价 格:¥电议型 号:T78173产 地:中国大陆
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T78039Acetyl-(D-Arg2)-GRF (1-29) amide (human);化合物 Acetyl-(D-Arg2)-GRF (1-29) amide (human)Acetyl-(D-Arg2)
Acetyl-(D-Arg2)-GRF (1-29) amide (human) serves as an antagonist to growth hormone-releasing factor (GRF) and inhibits growth hormone (GH) secretion, with applications in endocrine research [1].
价 格:¥电议型 号:T78039产 地:中国大陆
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T78035[K15,R16,L27]VIP(1-7)/GRF(8-27) acetate;化合物 [K15,R16,L27]VIP(1-7)/GRF(8-27) acetate[K15,R16,L27]VIP(
[K15,R16,L27]VIP(1-7)/GRF(8-27) (acetate) is an acetate salt form of the peptide [K15,R16,L27]VIP(1-7)/GRF(8-27). This compound acts as a selective agonist for the VIP 1 receptor, displaying IC50 values of 2 nM for human VIP 1, 1 nM for rat VIP 1, and 30,000 nM for rat VIP 2 receptors [1]. The peptide´s acronym, VIP, stands for Vasoactive Intestinal Polypeptide.
价 格:¥电议型 号:T78035产 地:中国大陆
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T78030GRGESP;化合物 GRGESPGRGESP
GRGESP is a collagen gel contraction inhibitor that impedes the spreading of human fibroblasts within collagen gels and significantly reduces gel contraction, thus serving as a valuable agent for research in connective tissue morphogenesis [1].
价 格:¥电议型 号:T78030产 地:中国大陆
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T77994Grb2 SH2 domain inhibitor 1 TFA;化合物 Grb2 SH2 domain inhibitor 1 TFAGrb2 SH2 domain inhibitor 1 TFA
Grb2 SH2 Domain Inhibitor 1 TFA is a cyclic cell-penetrating peptide (CPP) featuring a conformationally restricted d-pro-l-pro motif ring (AF Φ Rpprrfq), where Φ represents L-naphthylalanine, R signifies D-arginine, and P stands for D-proline. It primarily functions as a cyclic peptide inhibitor.
价 格:¥电议型 号:T77994产 地:中国大陆
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T77976PROTAC Her3 Degrader-8;化合物 PROTAC Her3 Degrader-8PROTAC Her3 Degrader-8
PROTAC Her3 Degrader-8 (Compound PP2) is a proteolysis targeting chimera (PROTAC) capable of degrading the Her3 protein in vitro and within cellular assays, with potential to investigate diseases modulated by HER family proteins [1].
价 格:¥电议型 号:T77976产 地:中国大陆
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T77975PROTAC BRD9 Degrader-6;化合物 PROTAC BRD9 Degrader-6PROTAC BRD9 Degrader-6
PROTAC BRD9 Degrader-6, with an IC50 value of 0.13 nM, is a potent degrader of BRD9 suitable for research on BAF complex-related disorders [1].
价 格:¥电议型 号:T77975产 地:中国大陆
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T77974PROTAC BCR-ABL Degrader-1;化合物 PROTAC BCR-ABL Degrader-1PROTAC BCR-ABL Degrader-1
PROTAC BCR-ABL Degrader-1 (compound PROTAC 1), featuring a 2-oxoethyl linker, promotes Bcr-Abl degradation through the ubiquitin-proteasome pathway and demonstrates antiproliferative effects on K562 cells, suggesting its utility in cancer research [1].
价 格:¥电议型 号:T77974产 地:中国大陆
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T77936PROTAC BRD9 Degrader-4;化合物 PROTAC BRD9 Degrader-4PROTAC BRD9 Degrader-4
PROTAC BRD9 Degrader-4 is a bifunctional degrader targeting BRD9, designed for cancer research applications.
价 格:¥电议型 号:T77936产 地:中国大陆
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T77931PROTAC IRAK3 degrade-1 formic;化合物 PROTAC IRAK3 degrade-1 formicPROTAC IRAK3 degrade-1 formic
PROTAC IRAK3 Degrade-1 (Compound 23) is a selective and potent IRAK3 degrader, demonstrating an IC50 value of 5 nM [1].
价 格:¥电议型 号:T77931产 地:中国大陆
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T77926PROTAC KRAS G12C degrader-1;化合物 PROTAC KRAS G12C degrader-1PROTAC KRAS G12C degrader-1
PROTAC KRAS G12C degrader-1, a cereblon-based degrader, promotes CRBN/KRAS G12C dimerization and facilitates the degradation of GFP-KRAS G12C in reporter cells [1].
价 格:¥电议型 号:T77926产 地:中国大陆
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T77922HDAC6 degrader-1;化合物 HDAC6 degrader-1HDAC6 degrader-1
HDAC6 degrader-1, a proteolysis-targeting chimeric molecule (PROTAC), incorporates the selective HDAC6 inhibitor Nexturastat A (Nex A) for HDAC6 binding, a linker, and an E3 ligase recruiting ligand. This compound effectively induces HDAC6 degradation, displays superior selectivity over other HDAC isoforms, and efficiently inhibits cell proliferation [1].
价 格:¥电议型 号:T77922产 地:中国大陆
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T7772Fast Green FCF;固绿 FCFC.I. 42053|||Food green 3|||FD&C Green No. 3;C.I. 42053|||固绿 FCF|||Food green 3
Fast Green FCF (FD&C Green No. 3), a safe biocompatible color additive, has been suggested to mitigate chronic pain.
价 格:¥电议型 号:T7772产 地:中国大陆
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T77172Eflapegrastim;化合物 EflapegrastimEflapegrastim
Eflapegrastim, a humanized IgG4 monoclonal antibody and granulocyte colony-stimulating factor (G-CSF), targets the G-CSF receptor (c-Fms). It promotes the proliferation and differentiation of neutrophil progenitor cells, ensuring a stable count of mature and functional neutrophils, and effectively shortens the duration of neutropenia [1].
价 格:¥电议型 号:T77172产 地:中国大陆
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T77029Gremubamab;化合物 GremubamabGremubamab
Gremubamab (MEDI3902), a humanized IgG1 kappa anti-PcrV/Psl monoclonal antibody, specifically targets and binds to the Pseudomonas aeruginosa PcrV protein and Psl exopolysaccharide. It shows promise for the study of Pseudomonas aeruginosa infections [1] [2].
价 格:¥电议型 号:T77029产 地:中国大陆