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  • T76877Vofatamab;沃凡妥单抗RG-7444|||B-701|||MFGR-1877S;RG-7444|||B-701|||MFGR-1877S

    Vofatamab (B-701) is a fully human monoclonal antibody targeting FGFR3. Vofatamab has potential anticancer and antitumor activity and is often used in combination with other compounds to treat cancer.

    价 格:¥电议型 号:T76877产 地:中国大陆

  • T76855Gresonitamab;化合物 GresonitamabGresonitamab

    Gresonitamab (AMG 910), a half-life extended (HLE) bispecific T-cell engager (BiTE) antibody, specifically targets CD3-positive T cells and CLDN18.2-expressing tumor cells, offering potential research applications in adenocarcinoma [1].

    价 格:¥电议型 号:T76855产 地:中国大陆

  • T76774Ponsegromab;Ponsegromab单抗PF 06946860;PF 06946860

    Ponsegromab (PF 06946860) is a selective and effective humanized anti-GDF15 antibody inhibitor. Ponsegromab has anti-cachexic activity by binding to GDF15 to prevent its binding to GFRAL, thus disrupting GDF15/GFRAL mediated signaling. Ponsegromab has potential anticancer activity and can be used to treat cancer patients with cancer anorexia cachexia syndrome.

    价 格:¥电议型 号:T76774产 地:中国大陆

  • T76568Aminopeptidase N Ligand (CD13) NGR peptide;化合物 Aminopeptidase N Ligand (CD13) NGR peptideAminopeptid

    Aminopeptidase N Ligand (CD13) NGR peptide, a polypeptide that targets CD13, functions as a carrier for mediating intracellular transmission and is commonly utilized in cancer research [1] [2].

    价 格:¥电议型 号:T76568产 地:中国大陆

  • T76539Insulin-like growth factor II;化合物 Insulin-like growth factor IIInsulin-like growth factor II

    Insulin-like Growth Factor II (IGF-2), the primary somatomedin in human serum, exerts both permissive and direct influences on neurite outgrowth and significantly improves the survival of sympathetic and sensory neurons [1] [2].

    价 格:¥电议型 号:T76539产 地:中国大陆

  • T76431GR 83074;化合物 GR 83074GR 83074

    GR 83074 is a potent and selective antagonist of the NK-2 (Neurokinin Receptor), demonstrating a selectivity factor of 340-fold over NK-1, with a pK B value of 8.23. It does not act as an antagonist for NK-3, affirming its specificity [1].

    价 格:¥电议型 号:T76431产 地:中国大陆

  • T76430GR 87389;化合物 GR 87389GR 87389

    GR 87389, a potent NK2 receptor antagonist, competitively inhibits GA 64349-induced contractions in smooth muscle strips of the human detrusor, prostate, and prostatic urethra [1] [2].

    价 格:¥电议型 号:T76430产 地:中国大陆

  • T76321Brain Derived Basic Fibroblast Growth Factor (1-24);化合物 Brain Derived Basic Fibroblast Growth Factor

    Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24), a synthetic peptide, exhibits anti-bacterial and anti-HBV properties, finding application in infectious and immune disease research [1].

    价 格:¥电议型 号:T76321产 地:中国大陆

  • T76306Adipokinetic hormone I (Locusta migratoria);化合物 Adipokinetic hormone I (Locusta migratoria)Adipokine

    Adipokinetic hormone I (Locusta migratoria) (Lom-AKH-I), an insect adipokinetic hormone (AKH), increases fat body cAMP levels in vitro. AKHs regulate the mobilization of carbohydrates and lipids from fat body stores for flight, through AKH receptor(s)´ association with cAMP production and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs) [1] [3].

    价 格:¥电议型 号:T76306产 地:中国大陆

  • T76304Adipokinetic hormone II (Locusta migratoria);化合物 Adipokinetic hormone II (Locusta migratoria)Adipoki

    Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II), an insect adipokinetic hormone (AKH), elevates fat body cAMP levels in vitro. These hormones (AKHs) regulate the mobilization of carbohydrates and lipids from fat body reserves for flight, by activating AKH receptor(s) that stimulate cAMP production and glycogen phosphorylase through the stimulatory guanine nucleotide-binding protein (Gs) [1] [3].

    价 格:¥电议型 号:T76304产 地:中国大陆

  • T76301Agouti-related Protein (AGRP) (83-132) Amide (human);化合物 Agouti-related Protein (AGRP) (83-132) Amid

    Agouti-related Protein (AGRP) (83-132) Amide (human) is a segment derived from the agouti-related protein (AGRP), abundantly present in the hypothalamus´ arcuate nucleus. It predominantly functions as an inverse agonist for the melanocortin-4 receptor (MC4R), thereby promoting food intake [1] [2].

    价 格:¥电议型 号:T76301产 地:中国大陆

  • T76262LCagrilintide acetate;化合物 Cagrilintide acetateCagrilintide acetate

    Cagrilintide acetate, a long-acting acylated amylase analogue and non-selective AMYR/CTR agonist, effectively reduces food intake and induces significant weight loss in a dose-dependent manner, making it a valuable compound for obesity research [1] [2] [3].

    价 格:¥电议型 号:T76262L产 地:中国大陆

  • T76262Cagrilintide;化合物 CagrilintideCagrilintide

    Cagrilintide, an investigational novel long-acting acylated amylin analogue, functions as an agonist for nonselective amylin receptors (AMYR) and the calcitonin G protein-coupled receptor (CTR). It significantly reduces food intake and induces weight loss, showing promise for obesity research [1] [2] [3].

    价 格:¥电议型 号:T76262产 地:中国大陆

  • T76095Granuliberin R;化合物 Granuliberin RGranuliberin R

    Granuliberin R, a dodecapeptide derived from the skin of the frog Rana rugosa, is a novel amphibian-origin mast cell degranulating peptide. It has the ability to target rat peritoneal mast cells, prompting them to release granules and histamine [1] [2].

    价 格:¥电议型 号:T76095产 地:中国大陆

  • T76078Neurogranin (48-76), mouse;化合物 Neurogranin (48-76), mouseNeurogranin (48-76), mouse

    Neurogranin (48-76), mouse, is a peptide comprising residues 48-76 of Neurogranin, a post-synaptically exclusive calmodulin-binding protein that mediates NMDAR-driven synaptic plasticity by regulating the calcium-calmodulin (Ca2+-CaM) pathway [1].

    价 格:¥电议型 号:T76078产 地:中国大陆

  • T76032Calcitonin Gene Related Peptide (CGRP) II, rat TFA;化合物 Calcitonin Gene Related Peptide (CGRP) II, ra

    Calcitonin Gene-Related Peptide (CGRP) II, rat TFA, functions as a potent and enduring vasodilator by activating CGRP receptors. This compound is utilized in cardiovascular disease research [1].

    价 格:¥电议型 号:T76032产 地:中国大陆

  • T76007RGD peptide (GRGDNP) (TFA);化合物 RGD peptide (GRGDNP) (TFA)RGD peptide (GRGDNP) (TFA)

    RGD peptide (GRGDNP) TFA functions as an inhibitor of integrin-ligand interactions, competitively blocking α5β1´s interaction with the extracellular matrix (ECM). It induces apoptosis by triggering conformational changes that facilitate pro-caspase-3 activation and autoprocessing. Furthermore, RGD peptide (GRGDNP) TFA is critical in regulating cell adhesion, migration, growth, and differentiation [1] [2] [3].

    价 格:¥电议型 号:T76007产 地:中国大陆

  • T75978β-CGRP, human TFA;化合物 β-CGRP, human TFAβ-CGRP, human TFA

    Human β-CGRP TFA (β-CGRP, human TFA) is a calcitonin peptide that functions through interaction with the calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP) complex, demonstrating IC50 values of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2, respectively, in cellular assays [1].

    价 格:¥电议型 号:T75978产 地:中国大陆

  • T75935GRK2i TFA;化合物 GRK2i TFAGRK2i TFA

    GRK2i TFA, a GRK2 inhibitory polypeptide, specifically targets and inhibits the activation of GRK2 by Gβγ. It mimics the Gβγ-binding domain, functioning as a cellular antagonist of Gβγ [1].

    价 格:¥电议型 号:T75935产 地:中国大陆

  • T75910GR231118 TFA;化合物 GR231118 TFAGR231118 TFA

    GR231118 TFA, a neuropeptide Y C-terminus analogue, acts as a potent, competitive, and relatively selective antagonist at the human neuropeptide YY receptor, exhibiting a pKi of 10.4. It serves as a strong agonist at the human neuropeptide YY4 receptor with a pEC50 of 8.6 and a pKi of 9.6, while demonstrating weak agonistic activity at both human and rat neuropeptide YY2 and YY5 receptors. Additionally, this compound shows high affinity for the mouse neuropeptide YY6 receptor, with a pKi value o

    价 格:¥电议型 号:T75910产 地:中国大陆

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