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T9767CC618CC618,CC-618
CC618 is a selective PPARβ/δ antagonist with an IC50 of 10.0 μM.
价 格:¥电议型 号:T9767产 地:中国大陆
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T9765TJ-M2010-5ischemia,MIRI,Anoxia,factor,MyD88,injury,reoxygenation,inhibit,reperfusion,differentiation
TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain to interfere with its homodimerization and suppress MyD88 signaling. TJ-M2010-5 can be used in myocardial ischemia/reperfusion injury studies.
价 格:¥电议型 号:T9765产 地:中国大陆
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T8976PD-089828EGFR,ATP,nonselective,PD 089828,PDGFR,autophosphorylation,PD089828,HER1,Epidermal growth fa
PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 μM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 = 0.18 μM)
价 格:¥电议型 号:T8976产 地:中国大陆
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T6976SB 239063inhibit,SB 239063,SB-239063,Inhibitor,Autophagy,p38 MAPK
SB239063 is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.
价 格:¥电议型 号:T6976产 地:中国大陆
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T9760IC 86621ATP,Buchwald-Hartwig amination,Inhibitor,IC-86621,IC86621,IC 86621,DSB,antitumor,inhibit,Apo
IC 86621 is a selective and reversible ATP-competitive inhibitor of DNA-PK with an IC50 of 120 nM. IC 86621 increases DNA double-strand break(DSB)-induced antitumor activity with an EC50 of 68 ?M for DNA-PK mediated cellular DSB repair.
价 格:¥电议型 号:T9760产 地:中国大陆
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T10964DB1976DB1976,DB-1976
DB1976 is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. DB1976 potently inhibits PU.1 binding (IC50 of 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-λB affinity, KD of 12 nM) in vitro. DB1976 has Apoptosis-inducing effect.
价 格:¥电议型 号:T10964产 地:中国大陆
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T7976Erythorbic Acidfood,Inhibitor,D-Isoascorbic acid,additive,inhibit,Erythorbic Acid,D-Araboascorbic ac
Erythorbic Acid is an antiscorbutic agent
价 格:¥电议型 号:T7976产 地:中国大陆
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T6636RefametinibMEK1,allosteric,RDEA 119,BAY-869766,inhibit,Inhibitor,MAP2K,MEK2,orally,MAPKK,RDEA-119,Mi
Refametinib (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 (IC50: 19/47 nM).
价 格:¥电议型 号:T6636产 地:中国大陆
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T39762AHR antagonist 5 free baseAHR antagonist 5 free base
AHR antagonist 5 free base is an orally active antagonist of AHR with IC50s of ~35-150 nM in human and rodent cell lines.
价 格:¥电议型 号:T39762产 地:中国大陆
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T9976OBX02-011
OBX02-011 is an effective and reversible inhibitor of EGFR tyrosine kinase with IC50s of 0.134 and 2.09 nM for triple mutants Del19/T790M/C797S and L858R/T790M/C797S.
价 格:¥电议型 号:T9976产 地:中国大陆
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T23764AZ3976
AZ3976 is an inhibitor of PAI-1 with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 displays profibrinolytic activities.
价 格:¥电议型 号:T23764产 地:中国大陆
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T7954YM976YM-976,Phosphodiesterase (PDE),PDE4 inhibitor,inhibit,phosphodiesterase 4,anti-inflammatory act
YM976 is an orally active PDE4 inhibitor (IC50:2.2 nM)
价 格:¥电议型 号:T7954产 地:中国大陆
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T9762Upidosin
Upidosin is a potential uroselective α1-adrenoceptor antagonist, α1a subtype Ki=0.34 nM, α1b subtype Ki=3.9 nM, α1d subtype Ki=1.5 nM, α2-adrenoceptor Ki=33.3 nM.
价 格:¥电议型 号:T9762产 地:中国大陆
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T9847TLC2976-0103TLC2976 0103,TLC29760103
ROCK1-IN-1 is an inhibitor of ROCK1 with a K i value of 540 nM. ROCK1-IN-1 can be used in the research of hypertension, glaucoma and erectile dysfunction [1].
价 格:¥电议型 号:T9847产 地:中国大陆
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T7184FirsocostatND 630,Firsocostat,Acetyl-CoA Carboxylase,NDI 010976,inhibit,NDI010976,ACC, Acetyl Coenzy
ND-630 is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)
价 格:¥电议型 号:T7184产 地:中国大陆
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T7315BAY1125976inhibit,Inhibitor,Protein kinase B,Akt,BAY 1125976,BAY1125976,PKB,BAY-1125976
BAY1125976 is an allosteric inhibitor of Akt1 and Akt2 (IC50s of 5.2 and 18 nM, respectively, in a time-resolved FRET assay)
价 格:¥电议型 号:T7315产 地:中国大陆
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TP1458LArg-Gly-Glu-Ser acetate(93674-97-6 free base)ArgGlyGluSer acetate(93674976 free base),Arg Gly Glu Se
Arg-Gly-Glu-Ser acetate is a RGD related peptide that is a control for the RGDS activity of fibrinogen binding to activated platelets.
价 格:¥电议型 号:TP1458L产 地:中国大陆
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T9768LNinerafaxstat trihydrochlorideNinerafaxstat trihydrochloride
Ninerafaxstat trihydrochloride shifts cellular metabolism to glucose oxidation from fatty acid oxidation. Ninerafaxstat trihydrochloride improves overall mitochondrial respiration and reduces fatty acid oxidation, thereby inhibiting the proliferation and growth of cancer cells.
价 格:¥电议型 号:T9768L产 地:中国大陆
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T9575MRTX9768SDMA,toxicity,glioblastoma,orally,MRTX9768,low,Inhibitor,hematological,MRTX-9768,MTAP,CDKN2A
MRTX-9768 is a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAP/CDKN2A-deleted tumors.
价 格:¥电议型 号:T9575产 地:中国大陆
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T9766GW590735lipid,LDLc,GW-590735,GW 590735,HDLc,Peroxisome proliferator-activated receptors,GW590735,PPA
GW590735 is an effective and selective PPARα agonist with an EC50 of 4 nM on PPARα and at least 500-fold selectivity versus PPARδ and PPARγ. GW590735 can be used in dyslipidemia studies.
价 格:¥电议型 号:T9766产 地:中国大陆