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T40976Syk Kinase Peptide Substrate;Syk Kinase Peptide SubstrateSyk Kinase Peptide Substrate
Syk Kinase Peptide Substrate is a Syk kinase peptide substrate.
价 格:¥电议型 号:T40976产 地:中国大陆
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T39976MS67;MS67MS67
MS67 is a potent and selective degrader of the WD40 repeat domain protein 5 (WDR5) with a dissociation constant (Kd) of 63 nM. It exhibits no activity against protein methyltransferases, kinases, G-protein-coupled receptors (GPCRs), ion channels, and transporters. Notably, MS67 demonstrates significant anticancer properties.
价 格:¥电议型 号:T39976产 地:中国大陆
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T39955JNJ-67569762;JNJ-67569762JNJ-67569762
JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket ( IC 50 = 2.7 nM).
价 格:¥电议型 号:T39955产 地:中国大陆
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T39769DDO-2093;DDO-2093DDO-2093
DDO-2093, a powerful inhibitor of the MLL1-WDR5 protein-protein interaction (IC50 = 8.6 nM; Kd = 11.6 nM), exhibits prominent antitumor effects. Notably, DDO-2093 selectively hampers the catalytic activity of the MLL complex.
价 格:¥电议型 号:T39769产 地:中国大陆
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T39767AR-C141990 hydrochloride;AR-C141990 hydrochlorideAR-C141990 hydrochloride;AR-C141990 hydrochloride
AR-C141990 hydrochloride is a potent inhibitor of lactate transporters known as monocarboxylate transporters (MCTs). It has pK i values of 7.6 and 6.6 for MCT-1 and MCT-2, respectively. Additionally, this compound exhibits immunosuppressive properties and effectively inhibits the graft versus host response.
价 格:¥电议型 号:T39767产 地:中国大陆
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T39766Nor-NOHA monoacetate;nor-NOHA醋酸盐Nor NOHA monoacetate|||Nω-Hydroxy-nor-L-arginine monoacetate;Nor NOH
nor-NOHA monoacetate (Nω-Hydroxy-nor-L-arginine) is a highly potent and selective arginase inhibitor. nor-NOHA monoacetate inhibits rat hepatic arginase and inhibits the hydrolysis of L-arginine, which can be used to study cardiovascular and obstructive airway diseases.
价 格:¥电议型 号:T39766产 地:中国大陆
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T39765Mal-PEG1-Val-Cit-PAB-PNP;Mal-PEG1-Val-Cit-PAB-PNPMal-PEG1-Val-Cit-PAB-PNP;Mal-PEG1-Val-Cit-PAB-PNP
Mal-PEG1-Val-Cit-PAB-PNP is an ADC linker employed in the synthesis of ADCs, enabling cleavage.
价 格:¥电议型 号:T39765产 地:中国大陆
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T39764KER047;化合物 KER047ALK2-IN-4;ALK2-IN-4
KER047 (ALK2-IN-4) is an ALK2 inhibitor with potential anticancer activity and can be used in the study of non-small cell lung cancer.
价 格:¥电议型 号:T39764产 地:中国大陆
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T39763Rucosopasem manganese;Rucosopasem manganeseGC4711;GC4711
Rucosopasem manganese (GC4711) is a potent, selective superoxide dismutase (SOD) mimetic capable of efficiently converting superoxide to hydrogen peroxide. This compound, specifically designed for research purposes, holds promise in cancer-related studies.
价 格:¥电议型 号:T39763产 地:中国大陆
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T39762AHR antagonist 5 free base;化合物AHR antagonist 5 free baseAHR antagonist 5 free base
AHR antagonist 5 free base is an orally active antagonist of AHR with IC50s of ~35-150 nM in human and rodent cell lines.
价 格:¥电议型 号:T39762产 地:中国大陆
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T39761BIIB091;BIIB091BIIB091
BIIB091 is a highly selective, reversible BTK inhibitor for treating autoimmune diseases.
价 格:¥电议型 号:T39761产 地:中国大陆
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T39760BAY-6672;BAY-6672BAY-6672
BAY-6672 is a highly potent and selective antagonist of the human Prostaglandin F (FP) receptor, displaying an IC 50 value of 11 nM.
价 格:¥电议型 号:T39760产 地:中国大陆
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T3976Cytosporone B;化合物Cytosporone BCsn-B|||Dothiorelone G;Csn-B|||Dothiorelone G
Cytosporone B (Dothiorelone G) is a naturally occurring agonist for the nuclear receptor Nur77 (IC50 = 0.278 nM). Activation of Nur77 with cytosporone B induces the expression of Nur77-dependent genes, including the gene for Nur77 itself. Signaling through Nur77 induces apoptosis in cancer cells and retards xenograft tumor growth. It also induces genes related to gluconeogenesis and decreases atherosclerosis progression in mice fed a high fat and high cholesterol diet. Cytosporone B is brain pen
价 格:¥电议型 号:T3976产 地:中国大陆
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T38976MUC1, mucin core;MUC1, mucin coreMUC1, mucin core;MUC1, mucin core
MUC1, mucin core is a type I transmembrane glycoprotein that is characterized by its overexpression and abnormal glycosylation in carcinoma cells. It specifically binds to domain 1 of ICAM-1.
价 格:¥电议型 号:T38976产 地:中国大陆
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T3797613(S)-HOTrE(γ);13(S)-HOTrE(γ)13(S)-HOTrE(γ)
13(S)-HOTrE(γ) is the 15-LO product of γ-linolenic acid. It is synthesized in human platelets, but its specific function is not known.
价 格:¥电议型 号:T37976产 地:中国大陆
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T36976SGC 6870;SGC 6870SGC 6870
Potent and selective protein arginine methyltransferase 6 (PRMT6) inhibitor (IC50 = 77 nM). Exhibits selectivity over all other PRMTs and 23 methyltransferases. In HEK293T cells overexpressing PRMT6, inhibits asymmetric dimethylation of H3R2 (IC50 = 0.8 μM) Negative control SGC 6870N also available.
价 格:¥电议型 号:T36976产 地:中国大陆
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T36630MRTX9768 hydrochloride;MRTX9768 hydrochlorideMRTX9768 hydrochloride
MRTX9768 hydrochloride is a potent, orally active PRMT5 inhibitor. MRTX9768 hydrochloride is a synthetic lethal-based inhibitor binding the PRMT5-MTA complex[1].
价 格:¥电议型 号:T36630产 地:中国大陆
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T359766-Formylpterin;6-Formylpterin6Formylpterin|||6 Formylpterin|||6-Formylpterin;6Formylpterin|||6 Formy
Xanthine oxidase (XO) generates reactive oxygen species, including hydrogen peroxide (H2O2), as it oxidizes specific substrates in the presence of water and oxygen. 6-Formylpterin is an oxidized pterin produced by photolytic breakdown of folic acid. It binds to one of two active sites on XO nearly quantitatively and irreversibly and prevents the metabolism of other substrates at the second site, resulting in hetero-substrate" inhibition at nanomolar concentrations. However
价 格:¥电议型 号:T35976产 地:中国大陆
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T34976U 75875;化合物 T34976U75875|||U-75875|||Pnu75875|||Pnu-75875|||Pnu 75875;U75875|||U-75875|||Pnu75875|||
U 75875 is a protease inhibitor.
价 格:¥电议型 号:T34976产 地:中国大陆
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T34366Ro 7-9767;化合物 T34366Ro7-9767|||Ro-7-9767;Ro7-9767|||Ro-7-9767
Ro 7-9767 is a biochemical.
价 格:¥电议型 号:T34366产 地:中国大陆