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产品数:86101
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T9826GDC-0214GDC0214,GDC 0214
GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).
价 格:¥电议型 号:T9826产 地:中国大陆
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T6843GDC-0623Mitogen-activated protein kinase kinase,Apoptosis,inhibit,MEK,Inhibitor,MAP2K,MAPKK,MEK inhi
GDC-0623 is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.
价 格:¥电议型 号:T6843产 地:中国大陆
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T6510GDC-0349Mammalian target of Rapamycin,GDC0349,GDC 0349,mTOR,inhibit,Autophagy,GDC-0349,Inhibitor
GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.
价 格:¥电议型 号:T6510产 地:中国大陆
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T64021GDC-6036-NH
GDC-6036-NH is a precursor compound for compound 17 a/b, derived from patent WO2020097537A2, where compound 17 a/b is a RAS inhibitor and can be used in cancer research.
价 格:¥电议型 号:T64021产 地:中国大陆
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TQ0242Fenebrutinibinhibit,Inhibitor,GDC0853,GDC 0853,Fenebrutinib,Btk,Bruton tyrosine kinase
Fenebrutinib is a selective and noncovalent Btk inhibitor (Ki: 0.91 nM).
价 格:¥电议型 号:TQ0242产 地:中国大陆
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TQ0071Navoximodinhibit,Indoleamine 2,3-Dioxygenase (IDO),GDC 0919,Inhibitor,Navoximod,NLG-?919,GDC0919
Navoximod (NLG- 919, GDC-0919) is a potent indoleamine-(2,3)-dioxygenase (IDO) pathway inhibitor (Ki/EC50: 7 nM/75 nM).
价 格:¥电议型 号:TQ0071产 地:中国大陆
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T6511RavoxertinibGDC 0994,Ravoxertinib,inhibit,Extracellular signal regulated kinases,GDC0994,Inhibitor,E
GDC-0994 is an effective and orally available ERK1/2 inhibitor (IC50: 1.1/0.3 nM).
价 格:¥电议型 号:T6511产 地:中国大陆
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T7300GDC-0575GDC 0575,GDC-0575,RG-7741,inhibit,ARRY575,Inhibitor,Checkpoint Kinase (Chk),ARRY 575,GDC0575
GDC-0575 is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).
价 格:¥电议型 号:T7300产 地:中国大陆
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T6320GDC-0879GDC 0879;GDC0879;AR-00341677
GDC-0879 is a novel, potent and selective B-Raf inhibitor with IC50 of 0.13 nM with activity against c-Raf as well.
价 格:¥电议型 号:T6320产 地:中国大陆
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T6252Ipatasertib帕他色替;RG7440;GDC-0068
Ipatasertib (GDC-0068), a highly specific pan-Akt inhibitor, targets Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM, respectively.
价 格:¥电议型 号:T6252产 地:中国大陆
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T5118BrilanestrantGDC0810;RG 6046;ARN-810;GDC-0810;GDC 0810
GDC-0810 is a selective estrogen receptor degrader (IC50: 0.7 nM).
价 格:¥电议型 号:T5118产 地:中国大陆
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T3985GDC-0326GDC 0326;GDC0326
GDC-0326 is a potent and selective inhibitor of α-Isoform of Phosphoinositide 3-Kinase (PI3Kalpha inhibitor).
价 格:¥电议型 号:T3985产 地:中国大陆
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T3705GDC0084RG7666;GDC-0084;GDC 0084
GDC-0084 (RG7666) is a PI3K inhibitor with potential antineoplastic activity. GDC-0084 specifically inhibits PI3K in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may res
价 格:¥电议型 号:T3705产 地:中国大陆
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T3623CobimetinibGDC-0973;RG7420;XL518;可美替尼;考比替尼
Cobimetinib is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) (IC50: 0.9 nM). Cobimetinib specifically binds to and inhibits the catalytic activity of MEK1, resulting in inhibition of extracellular signal-related kinase 2 (ERK2) ph
价 格:¥电议型 号:T3623产 地:中国大陆
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T27407GDC0575 monohydrochlorideGDC0575;ARRY-575;GDC-0575;GDC 0575;ARRY575
GDC-0575 is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2?nM. GDC-0575 specifically binds to and inhibits Chk1; this may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M pha
价 格:¥电议型 号:T27407产 地:中国大陆
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T223382,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamideGDC046
GDC046, a potent lead analog, has good kinase selectivity, physicochemical properties and pharmacokinetic profile.
价 格:¥电议型 号:T22338产 地:中国大陆
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T2119Venetoclax维奈妥拉;ABT 199;ABT199;GDC-0199;ABT-199
ABT-199 is a selective inhibitor of Bcl-2 (Ki < 0.010 nM), binding over 3 orders of magnitude less avidly to Bcl-xL, and Bcl-W (Kis = 48 and 245 nM, respectively).
价 格:¥电议型 号:T2119产 地:中国大陆
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T1999TaselisibRG-7604;GDC-0032
Taselisib is an orally bioavailable inhibitor of the class I phosphatidylinositol 3-kinase (PI3K) alpha isoform (PIK3CA), with potential antineoplastic activity.
价 格:¥电议型 号:T1999产 地:中国大陆
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T1994PictilisibRG7321;GDC-0941
Pictilisib (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).
价 格:¥电议型 号:T1994产 地:中国大陆