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  • T1916ApitolisibRG 7422；GDC-0980；GNE 390

    Apitolisib, an effective, class I PI3K inhibitor for PI3Kα（IC50=5 nM）, PI3Kβ（IC50=27 nM）, PI3Kδ（IC50=7 nM）, PI3Kγ （IC50=14 nM）, is used in trials study of solid cancers, breast cancer, prostate cancer, renal cell carcinoma, and endometrial carcinoma, amon

    价 格：￥电议型 号：T1916产 地：中国大陆

  • T1806IDO-IN-7NLG919；Navoximod；GDC-0919；NLG-919 analogue

    NLG919 is a potent IDO (indoleamine-(2, 3)-dioxygenase) pathway inhibitor.

    价 格：￥电议型 号：T1806产 地：中国大陆

  • T15375InavolisibRG6114；GDC-0077

    GDC-0077 is an orally available and selective inhibitor of PI3Kα (IC50=0.038 nM). GDC-0077 is more selective for mutant versus wild-type PI3Kα. GDC-0077 exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylati

    价 格：￥电议型 号：T15375产 地：中国大陆

  • T11399GiredestrantGDC-9545

    Giredestrant potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity. Giredestrant, a non-steroidal ER ligand, is an orally active and selective estrogen re

    价 格：￥电议型 号：T11399产 地：中国大陆

  • T11381Pictilisib dimethanesulfonateGDC-0941 2 MeSO3H salt；GDC-0941 dimethanesulfonate

    Pictilisib dimethanesulfonate is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold).

    价 格：￥电议型 号：T11381产 地：中国大陆

  • T10856Cobimetinib R-enantiomerCobimetinib R-enantiomer,GDC-0973 R-enantiomer,XL-518 R-enantiomer

    Cobimetinib R-enantiomer is the less active R-enantiomer of Cobimetinib which is a selective MEK inhibitor.

    价 格：￥电议型 号：T10856产 地：美洲

  • T11378GDC-0834 S-enantiomerGDC-0834 S-enantiomer

    ?GDC-0834 is a potent and selective BTK inhibitor.GDC-0834 (S-enantiomer) is the S-enantiomer of GDC-0834.

    价 格：￥电议型 号：T11378产 地：美洲

  • T11378LGDC-0834 RacemateGDC-0834 Racemate

    GDC-0834 Racemate is the racemate form of GDC-0834, which is an effective and selective BTK inhibitor

    价 格：￥电议型 号：T11378L产 地：美洲

  • T11379GDC-0834GDC-0834

    ?GDC-0834 inhibits BTK with an in vitro IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivo IC50 of 1.1 and 5.6 μM in mouse and rat, respectively.?GDC-0834 is a potent and selective BTK inhib

    价 格：￥电议型 号：T11379产 地：美洲

  • T11380GDC-0927GDC-0927,SRN-927,

    GDC-0927 is a novel,non-steroidal, ?potent, orally bioavailable, selective estrogen receptor antagonist.?

    价 格：￥电议型 号：T11380产 地：美洲

  • T11381Pictilisib dimethanesulfonatePictilisib dimethanesulfonate,GDC-0941 dimethanesulfonate,GDC-0941 2 Me

    ?Pictilisib dimethanesulfonate is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold).?

    价 格：￥电议型 号：T11381产 地：美洲

  • T15018CUDC-427CUDC-427,GDC-0917,

    CUDC-427 is a antagonist of second-generation pan-selective IAP. It is used for treatment of various cancers.

    价 格：￥电议型 号：T15018产 地：美洲

  • T15375GDC-0077GDC-0077,RG6114,

    GDC-0077 is an orally available and selective inhibitor of PI3Kα (IC50=0.038 nM). GDC-0077 is more selective for mutant versus wild-type PI3Kα. GDC-0077 exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylati

    价 格：￥电议型 号：T15375产 地：美洲

  • T15376GDC-0339GDC-0339

    GDC-0339 is discovered as a potential treatment of multiple myeloma. GDC-0339 is an orally bioavailable and well-tolerated inhibitor of pan-Pim kinase (Kis: 0.03 nM, 0.1 nM and 0.02 nM for Pim1, Pim2 and Pim3, respectively).

    价 格：￥电议型 号：T15376产 地：美洲

  • T15377Ravoxertinib hydrochlorideRavoxertinib hydrochloride,GDC-0994 (hydrochloride),

    Ravoxertinib hydrochloride is an orally bioavailable and selective inhibitor for ERK kinase activity (IC50: 6.1 nM and 3.1 nM for ERK1 and ERK2, respectively).

    价 格：￥电议型 号：T15377产 地：美洲

  • T1806NLG919NLG919,GDC-0919,IDO-IN-7

    NLG919 is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor.

    价 格：￥电议型 号：T1806产 地：美洲

  • T1994PictilisibPictilisib,GDC-0941,RG7321

    Pictilisib (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).

    价 格：￥电议型 号：T1994产 地：美洲

  • T1999TaselisibTaselisib,RG-7604,GDC-0032

    Taselisib is an orally bioavailable inhibitor of the class I phosphatidylinositol 3-kinase (PI3K) alpha isoform (PIK3CA), with potential antineoplastic activity.

    价 格：￥电议型 号：T1999产 地：美洲

  • T2590VismodegibVismodegib,GDC-0449,Erivedge

    Vismodegib is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM).

    价 格：￥电议型 号：T2590产 地：美洲

  • T5118GDC-0810GDC-0810,GDC0810,GDC 0810

    GDC-0810 is a selective estrogen receptor degrader (IC50: 0.7 nM).

    价 格：￥电议型 号：T5118产 地：美洲

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