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T16037GLN-1062;化合物GLN-1062GLN-1062
GLN-1062 is a pro-drug of galantamine and liberates galantamine on cleavage by a carboxyesterase in the brain.
价 格:¥电议型 号:T16037产 地:中国大陆
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T15962Mal-amido-PEG8-NHS ester;化合物Mal-amido-PEG8-NHS esterMal-amido-PEG8-NHS ester
Mal-amido-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T15962产 地:中国大陆
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T15942MK-7622;化合物MK-7622M1 receptor modulator;M1 receptor modulator
MK-7622 (M1 receptor modulator) is a modulator of muscarinic M1 receptor positive allosteric.
价 格:¥电议型 号:T15942产 地:中国大陆
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T15862m-PEG3-aminooxy-Boc;化合物 T15862m-PEG3-ONHBoc;m-PEG3-ONHBoc
m-PEG3-ONHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
价 格:¥电议型 号:T15862产 地:中国大陆
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T15806LY2562175;化合物LY2562175LY2562175
LY2562175 is an effective and selective FXR agonist (EC50: 193 nM).
价 格:¥电议型 号:T15806产 地:中国大陆
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T15762Lipoamido-PEG2-OH;化合物 T15762Lipoamido-PEG2-OH
Lipoamido-PEG2-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15762产 地:中国大陆
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T15686L-741626;化合物L-7416263-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole;3-(4-(4-Chlorophenyl-4-hy
L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3 and D4 receptors respectively).
价 格:¥电议型 号:T15686产 地:中国大陆
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T15662KIN1408;化合物 T15662KIN1408
KIN1408 is an antiviral small molecule compound. KIN1408 also is an agonist of the RLR pathway.
价 格:¥电议型 号:T15662产 地:中国大陆
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T15629JTE-013;化合物JTE-013JTE-013
JTE-013 is an effective and specific antagonist of S1P2. JTE-013 suppresses the specific binding of radiolabeled S1P to human and rat S1P2 (IC50s: 17 nM and 22 nM, respectively).
价 格:¥电议型 号:T15629产 地:中国大陆
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T15628JT010;化合物JT010JT010
JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).
价 格:¥电议型 号:T15628产 地:中国大陆
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T15627(S)-JQ-35化合物 T15627TEN-010
(S)-JQ-35 (TEN-010) is an inhibitor of the Bromodomain and Extra-Terminal (BET) family bromodomain-containing proteins. It has a potential antineoplastic activity.
价 格:¥电议型 号:T15627产 地:中国大陆
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T15626JPM-OEt;化合物 T15626JPM-OEt
JPM-OEt is a broad spectrum cysteine cathepsin inhibitor with antitumor activity. JPM-OEt binds covalently in the active site and irreversibly inhibits the cysteine cathepsin family.
价 格:¥电议型 号:T15626产 地:中国大陆
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T15625JNJ4796;化合物 T15625JNJ4796
JNJ4796 is an oral active fusion inhibitor of the influenza virus, by inhibiting hemagglutinin (HA)-mediated fusion to neutralizing the influenza A group 1 virus. JNJ4796 mimics the functionality of the broadly neutralizing antibodies (bnAbs).
价 格:¥电议型 号:T15625产 地:中国大陆
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T15624JNJ-64619178;化合物JNJ-64619178JNJ-64619178
JNJ-64619178 is a selective, orally active, and pseudo-irreversible inhibitor of protein arginine methyltransferase 5 (IC50: 0.14 nM). It has effective activity In lung cancer.
价 格:¥电议型 号:T15624产 地:中国大陆
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T15623JNJ-61432059;化合物JNJ-61432059JNJ-61432059
JNJ-61432059 is an oral active and selective negative modulator of TARP γ?8 Selective AMPAR(pIC50: 9.7).
价 格:¥电议型 号:T15623产 地:中国大陆
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T15622JNJ-54175446;化合物 JNJ-54175446JNJ-5446;JNJ-5446
JNJ-54175446 (JNJ-5446) is a CNS-permeable and selective P2X7 receptor antagonist that attenuates the release of IL-1β/IL-18 from microglia, and may be used in the study of depression.
价 格:¥电议型 号:T15622产 地:中国大陆
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T15621Rilematovir;化合物RilematovirJNJ-53718678|||JNJ-678;JNJ-53718678|||JNJ-678
Rilematovir (JNJ-678) is an inhibitor of fusion protein with antiviral activity and low cytotoxicity. Rilematovir can be used in studies about respiratory syncytial virus treatment.
价 格:¥电议型 号:T15621产 地:中国大陆
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T1562Rebamipide;瑞巴派特Proamipide|||OPC12759;Proamipide|||OPC12759|||瑞巴派特
Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis in the gastric mucosa. This agent also inhibits H. pylori-induced production of tumor necrosis factor (TNF) alpha and subsequent inflammation of the gastric mucosa. In addition, rebamipide scavenges oxygen-derived free radicals that potentially cause mucosal injury, and stimulate
价 格:¥电议型 号:T1562产 地:中国大陆
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T15618JNJ-46281222;化合物 T15618JNJ-46281222
JNJ-46281222 is an metabotropic glutamate (mGlu) 2-selective, highly potent PAM (positive allosteric modulator). It has nanomolar affinity (Kd = 1.7 nM) and a high modulatory potency (pEC50 = 7.71).
价 格:¥电议型 号:T15618产 地:中国大陆
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T15595LIRL-1620 acetate;化合物IRL-1620 acetateIRL-1620 acetate(142569-99-1 free base);IRL-1620 acetate(142569-
IRL-1620 acetate is an effective and selective agonist of Endothelin B receptor (ETB) with a Ki of 16 pM which is more selective than ETA with a Ki of 19 μM.
价 格:¥电议型 号:T15595L产 地:中国大陆