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T15595IRL-1620;化合物 T15595IRL-1620
IRL-1620 is an effective and selective agonist of endothelin receptor type B (ETB) (Ki: 16 pM).
价 格:¥电议型 号:T15595产 地:中国大陆
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T15562Imazamox;甲氧咪草烟CL29926|||(±)-Imazamox;CL29926|||甲氧咪草烟|||(±)-Imazamox
Imazamox ((±)-Imazamox) is a systemic herbicide with high selectivity, high activity, safety and broadspectrum activity. Imazamox inhibits the production of acetolactate synthase (ALS) in plants, which would then inhibit plant growth and ultimately lead to plant death.
价 格:¥电议型 号:T15562产 地:中国大陆
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T15462Haloxon;哈洛克酮Haloxon
Haloxon is an organophosphorus anthelmintic. Haloxon is used against nematodes of the abomasum and small intestine in ruminants.
价 格:¥电议型 号:T15462产 地:中国大陆
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T15444GSK962;化合物GSK962GSK962
GSK962 is a GSK963 inactive enantiomer. It can be used to confirm the on-target effects.
价 格:¥电议型 号:T15444产 地:中国大陆
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T15430GSK2256294A;化合物GSK2256294AGSK 2256294;GSK 2256294
GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.
价 格:¥电议型 号:T15430产 地:中国大陆
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T15422GSK-626616;化合物GSK-626616GSK-626616
GSK-626616 is a potent and orally bioavailable DYRK3 inhibitor (IC50: 0.7 nM). It inhibits other members of the DYRK family with similar potency. GSK-626616 is a potential therapy for the treatment of anemia.
价 格:¥电议型 号:T15422产 地:中国大陆
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T15418GS-6201;化合物GS-6201CVT-6883;CVT-6883
GS-6201 (CVT-6883) is a selective antagonist of adenosine A2B receptor. GS-6201 shows high affinity and selectivity for the human adenosine A2B receptors with a Ki of 22 nM.
价 格:¥电议型 号:T15418产 地:中国大陆
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T15362FX-11;化合物FX-11LDHA Inhibitor FX11;LDHA Inhibitor FX11
FX-11 (LDHA Inhibitor FX11) is A potent, selective and competitive specific inhibitor of lactate dehydrogenase A (LDHA) with a Ki of 8 μM. FX-11 can activate PKM2 (pyruvate kinase M2). FX-11 can reduce ATP levels, induce oxidative stress and ROS production, and cause cell death. FX-11 appeared antitumor activity during xenotransplantation of lymphoma and pancreatic cancer.
价 格:¥电议型 号:T15362产 地:中国大陆
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T15301Fluspirilene;氟司必林Redeptin|||R 6218;Redeptin|||R 6218
Fluspirilene (R 6218) is a non-competitive L-type calcium channel antagonist (IC50: 0.03 μM).Fluspirilene is a long-acting antipsychotic compound used in the treatment of schizophrenia.
价 格:¥电议型 号:T15301产 地:中国大陆
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T15270Fananserin;法南色林RP 62203;RP 62203|||法南色林
Fananserin is an effective, selective and oral active antagonist of 5-HT2 (Ki = 0.37 nM for the rat 5-HT2A). Fananserin is an antagonist of human D4 receptor (Ki = 2.93 nM).
价 格:¥电议型 号:T15270产 地:中国大陆
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T15262Vactosertib Hydrochloride化合物 T15262TEW-7197 Hydrochloride|||EW-7197 Hydrochloride
Vactosertib Hydrochloride is an orally active and ATP-competitive ALK5 inhibitor (IC50: 12.9 nM). It has potently antimetastatic activity and anticancer effect. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50: 17.3 nM).
价 格:¥电议型 号:T15262产 地:中国大陆
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T15162DPA-714;化合物DPA-714DPA-714
DPA-714 is a high affinity translocator protein (TSPO) ligand (Ki=7 nM). It is designed with a fluorine atom in its structure, allowing labelling with fluorine -18 and in vivo imaging using positron emission tomography. [18F]DPA-714 successfully assesses for the specific imaging of inflammation in various models of neuroinflammation and in a brain tumor model.
价 格:¥电议型 号:T15162产 地:中国大陆
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T15134Dipraglurant;化合物 T15134ADX48621;ADX48621
Dipraglurant is a negative allosteric regulator (NAM) of blood-brain barrier transmissible mGluR5 with effective, selective and oral activity, with an IC50 value of 21 nM. Dipraglurant can treat levodopa-induced dyskinesia in Parkinson´s disease (PD-LID).
价 格:¥电议型 号:T15134产 地:中国大陆
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T1512Rizatriptan benzoate;苯甲酸利扎曲坦MK-462 Benzoate;苯甲酸利扎曲坦|||MK-462 Benzoate
Rizatriptan benzoate (MK-462 Benzoate) selectively binds to and activates serotonin (5-HT) 1B receptors and 5-HT 1D receptors providing relief of migraine headaches.
价 格:¥电议型 号:T1512产 地:中国大陆
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T15062DBCO-NHCO-PEG4-amine;化合物 T15062DBCO-NHCO-PEG4-amine
DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively)[1].
价 格:¥电议型 号:T15062产 地:中国大陆
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T15028Cyclopropavir;化合物 T15028MBX-400|||Filociclovir|||ZSM-I-62;MBX-400|||Filociclovir|||ZSM-I-62
Cyclopropavir (Filociclovir; MBX-400) is a compound of broad-spectrum anti-herpesvirus. It has good antiviral activity against cytomegalovirus (CMV), herpes simplex virus (HHV)-6 and HHV-8 (EC50s: 0.7 μM to 8 μM).
价 格:¥电议型 号:T15028产 地:中国大陆
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T15004CP-532623;化合物 T15004CP-532623
CP-532623, a close structural analog of Torcetrapib, is a CETP inhibitor with highly lipophilic properties. It elevates high-density lipoprotein cholesterol.
价 格:¥电议型 号:T15004产 地:中国大陆
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T14967Cimlanod;化合物 T14967BMS-986231|||CXL-1427;BMS-986231|||CXL-1427
Cimlanod is a second-generation Nitroxyl (HNO) donor for heart failure with positive lusitropic and inotropic as well as vasodilatory effects. Cimlanod delivers HNO via pH-dependent chemical breakdown when exposed to the neutral pH environment of the bloodstream.
价 格:¥电议型 号:T14967产 地:中国大陆
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T14962CI-1044;化合物 T14962PD-189659;PD-189659
CI-1044 is an inhibitor of PDE4 (IC50s: 0.29, 0.08, 0.56, 0.09 μM for PDE4A5, PDE4B2, PDE4C2 and PDE4D3).
价 格:¥电议型 号:T14962产 地:中国大陆
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T1487Fluvastatin sodium;氟伐他汀钠XU 62320 sodium|||XU-62-320|||Fluvastatin sodium salt;XU 62320 sodium|||XU-6
Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lowering agent.
价 格:¥电议型 号:T1487产 地:中国大陆